| tollip(m) + IRAK1(h) <==> tollip(m):IRAK1(h) (binding)
|
IRAK1(h) + ATP --> IRAK1(h){p} + ADP (phosphorylation; automodification)
|
TLR4(h) + IRAK1(h) <==> TLR4(h):IRAK1(h) (binding)
|
IL-1RAcP(h) + IRAK1(h) <==> IL-1RAcP(h):IRAK1(h) (binding)
|
IRAK1(h) + TRAF6(h) <==> IRAK1(h):TRAF6(h) (binding)
|
MyD88(h) + IRAK1(h) <==> MyD88(h):IRAK1(h) (binding)
|
IRAK1(h) + TRAF6(m) + p62(h) <==> IRAK1(h):TRAF6(m):p62(h) (binding)
|
IL-1RI(h) + IL-1RAcP(h) + IRAK1(h) <==> IL-1RI(h):IL-1RAcP(h):IRAK1(h) (binding)
|
IRAK-4(h) + IRAK1(h) <==> IRAK-4(h):IRAK1(h) (binding)
|
TRAM(h) + IRAK1(h) <==> TRAM(h):IRAK1(h) (binding)
|
IL-1beta(h) + IL-1RI(h) + MyD88(h) + IRAK-4(h) + IRAK1(h) + TRAF6(h) <==> IL-1beta(h):IL-1RI(h):MyD88(h):IRAK-4(h):IRAK1(h):TRAF6(h) (binding)
|
TRAF6(h) + IRAK1(h) + IRAK-4(h) + Pellino1(h) <==> TRAF6(h):IRAK1(h):IRAK-4(h):Pellino1(h) (binding)
|
IRAK1(h) + Btk(h) <==> IRAK1(h):Btk(h) (binding)
|
STAT3(h) + IRAK1(h) <==> STAT3(h):IRAK1(h) (binding)
|
IKK-gamma(h) + IRAK1(h) <==> IKK-gamma(h):IRAK1(h) (binding)
|
IRAK1(h) + IRAK-4(h) <==> IRAK1(h):IRAK-4(h) (binding)
|
IRAK1(h) + Pellino2(h) <==> IRAK1(h):Pellino2(h) (binding)
|
IRAK1(h) + ATP --> IRAK1(h){pT209} + ADP (phosphorylation; automodification)
|
TRAF6(m.s.) + IRAK1(h) <==> TRAF6(m.s.):IRAK1(h) (binding)
|
TAK1(h) + TRAF6(h) + IRAK1(h) + Pellino3-isoform1(h) <==> TAK1(h):TRAF6(h):IRAK1(h):Pellino3-isoform1(h) (binding)
|
IL-1RI(h) + TRAF6(h) + IRAK1(h) <==> IL-1RI(h):TRAF6(h):IRAK1(h) (binding)
|
TAK1(h) + IRAK1(h) <==> TAK1(h):IRAK1(h) (binding)
|
IRAK1(h) + TAB2(h) <==> IRAK1(h):TAB2(h) (binding)
|
TAB2(h) + TAK1(h) + TRAF6(h) + IRAK1(h) <==> TAB2(h):TAK1(h):TRAF6(h):IRAK1(h) (binding)
|
IRAK1(h) + IRF-7(m) <==> IRAK1(h):IRF-7(m) (binding)
|
n IRAK1(h) <==> (IRAK1(h))n (binding)
|
CD11B(h) + IRAK1(h) <==> CD11B(h):IRAK1(h) (binding)
|
FADD(m.s.) + IRAK1(h) <==> FADD(m.s.):IRAK1(h) (binding)
|
FADD(h) + IRAK1(h) <==> FADD(h):IRAK1(h) (binding)
|
SIGIRR(h) + IRAK1(h) <==> SIGIRR(h):IRAK1(h) (binding)
|
IRAK1(h) + sumo1(h) --> IRAK1(h){sumo} (sumoylation)
|
Caspase-4(h) + IRAK1(h) <==> Caspase-4(h):IRAK1(h) (binding)
|
IRAK1(h) --> IL8(h) (transactivation)
|
IRAK1(h) --> NFKBIA(h) (transactivation)
|
IRAK1(h) --> JNK(h){p} (increase of phosphorylation)
|
IRAK1(h) --> ERK(h){p} (increase of phosphorylation)
|
IRAK1(h) --> p38(h){p} (increase of phosphorylation)
|
IRAK1(h) --> MMP-13(h) (increase of abundance)
|
IRAK1(h) --> c-Jun(h){p} (increase of phosphorylation)
|
IRAK1(h) --> ERK1(h){p} (increase of phosphorylation)
|
IRAK1(h) --> ERK2(h){p} (increase of phosphorylation)
|
IRAK1(h) + TRAF3(m.s.) <==> IRAK1(h):TRAF3(m.s.) (binding)
|
IRAK1(h) + n ubiquitin(h) --> IRAK1(h){ub{K63}(n)} (ubiquitination)
|
IRAK1(h) + ATP --> IRAK1(h){p} + ADP (phosphorylation)
|
IRAK1(h) + IKK-alpha(h) <==> IRAK1(h):IKK-alpha(h) (binding)
|
IRAK1(h) + IKK-beta(h) <==> IRAK1(h):IKK-beta(h) (binding)
|
IRAK1(h) + n ubiquitin(h) --> IRAK1(h){ub{K48}(n)} (ubiquitination)
|
TIRAP(m.s.) + IRAK1(h) <==> TIRAP(m.s.):IRAK1(h) (binding)
|
IRAK1(h) --> DEFB4(h) (transactivation)
|
IRAK1(h) --> Beta-defensin2(h) (increase of secretion)
|
IRAK1(h) --> IRAK1(h) (expression).
|
IL-1beta(h) --/ IRAK1(h) (decrease of abundance)
|
Pellino2(h) + ATP --IRAK1(h)--> Pellino2(h){p} + ADP (phosphorylation)
|
IRF-7(m.s.) + ATP --IRAK1(h)--> IRF-7(m.s.){p} + ADP (phosphorylation)
|
MBP(m.s.) + ATP --IRAK1(h)--> MBP(m.s.){p} + ADP (phosphorylation)
|
TIRAP(m.s.) + ATP --IRAK1(h)--> TIRAP(m.s.){pT28} + ADP (phosphorylation)
|
IRAK1-a(h) + Pellino3-isoform1(h) <==> IRAK1-a(h):Pellino3-isoform1(h) (binding)
|
IRAK1-a(h) + Pellino3-isoform2(h) <==> IRAK1-a(h):Pellino3-isoform2(h) (binding)
|
IRAK1-a(h) + TRAF6(h) <==> IRAK1-a(h):TRAF6(h) (binding)
|
Irak1-b(h) + IRAK1-a(h) <==> Irak1-b(h):IRAK1-a(h) (binding)
|
IRAK1-a(h) + ATP --> IRAK1-a(h){p} + ADP (phosphorylation; automodification)
|
IRAK1-a(h) + IKK-gamma(h) <==> IRAK1-a(h):IKK-gamma(h) (binding)
|
IRAK1-a(h) + bcl10(h) <==> IRAK1-a(h):bcl10(h) (binding)
|
IRAK1-a(h) + n ubiquitin(h) --E1(m.s.),Ubc13(h):Uev1(h),Pellino1(h)--> IRAK1-a(h){ub{K63}(n)} (ubiquitination)
|
IRAK1-a(h) + n ubiquitin(h) --E1(m.s.),Ubc13(h):Uev1(h),Pellino3-isoform2(h)--> IRAK1-a(h){ub}n (ubiquitination)
|
IRAK1-a(h) + n ubiquitin(h) --E1(m.s.),Cdc34(h),Pellino1(h)--> IRAK1-a(h){ub{K48}(n)} (ubiquitination)
|
IRAK1-a(h) + n ubiquitin(h) --E1(m.s.),UBE2D4(h),Pellino1(h)--> IRAK1-a(h){ub}n (ubiquitination)
|
IRAK1-a(h) + n ubiquitin(h) --E1(m.s.),Ubc5A(h),Pellino1(h)--> IRAK1-a(h){ub}n (ubiquitination)
|
IRAK1-a(h) + n ubiquitin(h) --E1(m.s.),Ubc5B(h),Pellino1(h)--> IRAK1-a(h){ub}n (ubiquitination)
|
IRAK1-a(h) + ATP --> IRAK1-a(h){p} + ADP (phosphorylation)
|
IRAK1-a(h) + n ubiquitin(h) --Pellino2(h){p}--> IRAK1-a(h){ub}n (ubiquitination)
|
IRAK1-a(h) + n ubiquitin(h) --Pellino2(h)--> IRAK1-a(h){ub{K63}(n)} (ubiquitination)
|
IRAK1-a(h) + n ubiquitin(h) --Pellino2(h)--> IRAK1-a(h){ub{K48}(n)} (ubiquitination)
|
IRAK1(h) --> IRAK1-a(h) (expression).
|
Pellino1(h) + ATP --IRAK1-a(h)--> Pellino1(h){p} + ADP (phosphorylation)
|
Pellino3-isoform2(h) + ATP --IRAK1-a(h)--> Pellino3-isoform2(h){p} + ADP (phosphorylation)
|
TRAF6(h) + Irak1-b(h) <==> TRAF6(h):Irak1-b(h) (binding)
|
Irak1-b(h) + IRAK1-a(h) <==> Irak1-b(h):IRAK1-a(h) (binding)
|
2 Irak1-b(h) <==> (Irak1-b(h))2 (binding)
|
tollip(h) + Irak1-b(h) <==> tollip(h):Irak1-b(h) (binding)
|
Irak1-b(h) + bcl10(m) <==> Irak1-b(h):bcl10(m) (binding)
|
IRAK1(h) --> Irak1-b(h) (expression).
|
IRAK1(h) --> Irak1(h) (expression).
|
IRAK1(m.s.) + IRAK1c(h) <==> IRAK1(m.s.):IRAK1c(h) (binding)
|
IRAK-2(m.s.) + IRAK1c(h) <==> IRAK-2(m.s.):IRAK1c(h) (binding)
|
MyD88(m.s.) + IRAK1c(h) <==> MyD88(m.s.):IRAK1c(h) (binding)
|
tollip(m.s.) + IRAK1c(h) <==> tollip(m.s.):IRAK1c(h) (binding)
|
TRAF6(m.s.) + IRAK1c(h) <==> TRAF6(m.s.):IRAK1c(h) (binding)
|
MyD88(h) + IRAK1c(h) <==> MyD88(h):IRAK1c(h) (binding)
|
tollip(h) + IRAK1c(h) <==> tollip(h):IRAK1c(h) (binding)
|
TRAF6(h) + IRAK1c(h) <==> TRAF6(h):IRAK1c(h) (binding)
|
IRAK1(h) --> IRAK1c(h) (expression).
|
IRAK1(h) --> IRAK1(h) (expression).
|
hsa-miR-146a --/ IRAK1(h) (increase of mRNA decay).
|
hsa-miR-146b --/ IRAK1(h) (increase of mRNA decay).
|
