| IL-8(h) + CXCR1(h) <==> IL-8(h):CXCR1(h) (binding)
|
CXCR1(h) --> PLCbeta3(r) (activation; phosphorylation)
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CXCR1(h) + ATP --> CXCR1(h){p} + ADP (phosphorylation)
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CXCR1(h) --> G-alpha-14(m) (activation)
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CXCR1(h) --> G-alpha-15(m) (activation)
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CXCR1(h) --> G-alpha-15(h) (activation)
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IL-8(rb) + CXCR1(h) <==> IL-8(rb):CXCR1(h) (binding)
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CXCR1(h) + beta-arrestin2(r) <==> CXCR1(h):beta-arrestin2(r) (binding)
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CXCR1(h) + beta-adaptin 2(r) <==> CXCR1(h):beta-adaptin 2(r) (binding)
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CXCR1(h) + transferrin(v.s.) <==> CXCR1(h):transferrin(v.s.) (binding)
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CXCR1(h) + G-alpha-i2(h) <==> CXCR1(h):G-alpha-i2(h) (binding)
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CXCR1(h) + RGS12(h) <==> CXCR1(h):RGS12(h) (binding)
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IL8RA(h) --> CXCR1(h) (expression).
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beta-arrestin1(r) --/ CXCR1(h) (inhibition; translocation)
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betaARK-1(r) --/ CXCR1(h) (inhibition; translocation)
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dynamin1(r) --/ CXCR1(h) (inhibition; translocation)
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NAP-2(m.s.) --/ CXCR1(h) (decrease of abundance)
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CTAP-III(m.s.) --/ CXCR1(h) (decrease of abundance)
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NAP-2-CTF(m.s.) --/ CXCR1(h) (decrease of abundance)
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CXCR1(h) + IL-8(h) <==> CXCR1(h):IL-8(h) (binding)
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CXCR1(h) + ATP --> CXCR1(h){p} + ADP (phosphorylation)
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CXCR1(h) --> ERK1(r){p} (increase of phosphorylation)
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CXCR1(h) --> ERK2(r){p} (increase of phosphorylation)
|
IL8RA(h) --> CXCR1(h) (expression).
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