| TNFR1(h) + IKK-beta(h) <==> TNFR1(h):IKK-beta(h) (binding)
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IKK-gamma(h) + IKK-beta(h) + IKK-alpha(h) <==> IKK-alpha(h):IKK-beta(h):(IKK-gamma(h))2 (binding)
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IKK-alpha(h) + IKK-beta(h) <==> IKK-alpha(h):IKK-beta(h) (binding)
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2 IKK-beta(h) + 2 IKK-gamma(h) <==> (IKK-beta(h):IKK-gamma(h))2 (binding)
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IKK-beta(h) + ATP --IKK-alpha(h){p}--> IKK-beta(h){p} + ADP (phosphorylation)
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TAK1a(h) + IKK-beta(h) <==> TAK1a(h):IKK-beta(h) (binding)
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IKK-beta(h) + ATP --TRAF6(m){ub{K63}(n)}:TAB2(h):TAK1(m):TAB1(h)--> IKK-beta(h){p} + ADP (phosphorylation)
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RKIP(r) + IKK-beta(h) <==> RKIP(r):IKK-beta(h) (binding)
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IKK-beta(h) + MEKK1(r) <==> IKK-beta(h):MEKK1(r) (binding)
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IKK-beta(h) + ATP --MEKK1(h)--> IKK-beta(h){p} + ADP (phosphorylation)
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p62(h):PKCzeta(r) + IKK-beta(h) <==> p62(h):PKCzeta(r):IKK-beta(h) (binding)
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p62(h):PKCiota(x) + IKK-beta(h) <==> p62(h):PKCiota(x):IKK-beta(h) (binding)
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PKCalpha(b) + IKK-beta(h) <==> PKCalpha(b):IKK-beta(h) (binding)
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IKK-beta(h) + ATP --PKCzeta(r)--> IKK-beta(h){p} + ADP (phosphorylation)
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IKK-beta(h) + IKK-gamma(m) <==> IKK-beta(h):IKK-gamma(m) (binding)
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IKK-beta(h) + IkappaB-alpha(h) <==> IKK-beta(h):IkappaB-alpha(h) (binding)
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TRIF(h) + IKK-beta(h) <==> TRIF(h):IKK-beta(h) (binding)
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TANK(h) + IKK-gamma(h) + IKK-beta(h) <==> TANK(h):IKK-gamma(h):IKK-beta(h) (binding)
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IKK-beta(h) + ATP --> IKK-beta(h){pY} + ADP (phosphorylation)
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Src(h) + IKK-beta(h) <==> Src(h):IKK-beta(h) (binding)
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IKK-beta(h) + 2 ATP --Src(h)--> IKK-beta(h){pY188}{pY189} + 2 ADP (phosphorylation)
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Ro52(h) + IKK-gamma(h) + IKK-beta(h) + IKK-alpha(h) + CBP(h) + TIF2(h) + SRC3(h) <==> Ro52(h):IKK-gamma(h):IKK-beta(h):IKK-alpha(h):CBP(h):TIF2(h):SRC3(h) (binding)
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IKK-gamma(h) + IKK-beta(h) + CBP(h) + SRC3(h) <==> IKK-gamma(h):IKK-beta(h):CBP(h):SRC3(h) (binding)
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IKK-gamma(h) + IKK-beta(h) + SRC3(h) <==> IKK-gamma(h):IKK-beta(h):SRC3(h) (binding)
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IKK-beta(h) + SRC3(h) <==> IKK-beta(h):SRC3(h) (binding)
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IKK-gamma(h) + IKK-beta(h) <==> IKK-gamma(h):IKK-beta(h) (binding)
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IKK-beta(h) + TRAF6(h) <==> IKK-beta(h):TRAF6(h) (binding)
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IKK-gamma(h) + IKK-beta(h) + IKK-alpha(h) + Hsp50(h) + Hsp90(h) <==> IKK-gamma(h):IKK-beta(h):IKK-alpha(h):Hsp50(h):Hsp90(h) (binding)
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IKK-beta(h) + 2 ATP --> IKK-beta(h){pS177}{pS181} + 2 ADP (phosphorylation)
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IKK-beta(h) + muc1(h) <==> IKK-beta(h):muc1(h) (binding)
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muc1(m.s.) + IKK-gamma(h) + IKK-beta(h) <==> muc1(m.s.):IKK-gamma(h):IKK-beta(h) (binding)
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IKK-beta(h) + ATP --> IKK-beta(h){pS181} + ADP (phosphorylation; automodification)
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IKAP(h) + RelA-p65(h) + NIK(h) + IKK-beta(h) + IKK-alpha(h) <==> IKAP(h):RelA-p65(h):NIK(h):IKK-beta(h):IKK-alpha(h) (binding)
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IKK-beta(h) + IKAP(h) <==> IKK-beta(h):IKAP(h) (binding)
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IKK-gamma(h) + IKK-beta(h) + muc1(h) <==> IKK-gamma(h):IKK-beta(h):muc1(h) (binding)
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IKK-beta(h) + hamartin(h) <==> IKK-beta(h):hamartin(h) (binding)
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IKK-beta(h) + ATP --> IKK-beta(h){p} + ADP (phosphorylation)
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IKK-beta(h) + FOXO3a(h) <==> IKK-beta(h):FOXO3a(h) (binding)
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STAP2(h) + IKK-beta(h) <==> STAP2(h):IKK-beta(h) (binding)
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IKK-beta(h) + FAF1(h) <==> IKK-beta(h):FAF1(h) (binding)
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IKK-gamma(h) + IKK-alpha(h) + IKK-beta(h) <==> IKK-gamma(h):IKK-alpha(h):IKK-beta(h) (binding)
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Alpha-catulin(m.s.) + IKK-beta(h) <==> Alpha-catulin(m.s.):IKK-beta(h) (binding)
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Alpha-catulin(h) + IKK-beta(h) <==> Alpha-catulin(h):IKK-beta(h) (binding)
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IKK-gamma(h) + IKK-beta(h) + IKK-alpha(h) + CIKS(h) <==> IKK-gamma(h):IKK-beta(h):IKK-alpha(h):CIKS(h) (binding)
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IRAK1(h) + IKK-beta(h) <==> IRAK1(h):IKK-beta(h) (binding)
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IKK-beta(h) + ATP --> IKK-beta(h){pS181} + ADP (phosphorylation)
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IKK-beta(h) + IkappaB-alpha(m.s.) <==> IKK-beta(h):IkappaB-alpha(m.s.) (binding)
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IKK-beta(h) --> PLAUR(h) (transactivation)
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IKBKB(h) --> IKK-beta(h) (expression).
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NF-kappaB1(h) + ATP --IKK-beta(h)--> NF-kappaB1(h){p} + ADP (phosphorylation)
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RelA-p65(h) + ATP --IKK-beta(h)--> RelA-p65(h){pS536} + ADP (phosphorylation)
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IkappaB-alpha(h) + ATP --IKK-beta(h)--> IkappaB-alpha(h){p} + ADP (phosphorylation)
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IkappaB-beta(h) + ATP --IKK-beta(h)--> IkappaB-beta(h){p} + ADP (phosphorylation)
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IRF-3(h) + ATP --IKK-beta(h)--> IRF-3(h){p} + ADP (phosphorylation)
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IkappaB-alpha(m.s.) + ATP --IKK-beta(h)--> IkappaB-alpha(m.s.){p} + ADP (phosphorylation)
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A20(h) + ATP --IKK-beta(h)--> A20(h){pS381} + ADP (phosphorylation)
|
IKK-gamma(h) + IKK-beta(h) <==> IKK-gamma(h):IKK-beta(h) (binding)
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IKK-beta(h) + NIBP(m) <==> IKK-beta(h):NIBP(m) (binding)
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IKK-beta(h) + 2 ATP --> IKK-beta(h){pS177}{pS181} + 2 ADP (phosphorylation)
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IKK-beta(h) + ATP --> IKK-beta(h){p} + ADP (phosphorylation; automodification)
|
IKK-beta(h) + ATP --> IKK-beta(h){p} + ADP (phosphorylation)
|
IKK-gamma(m.s.) + IKK-beta(h) <==> IKK-gamma(m.s.):IKK-beta(h) (binding)
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IKK-beta(h) + ubiquitin(h) --> IKK-beta(h){ub} (ubiquitination)
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STAP2(h) + IKK-beta(h) <==> STAP2(h):IKK-beta(h) (binding)
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MyD88(m.s.) + IKK-beta(h) <==> MyD88(m.s.):IKK-beta(h) (binding)
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IKK-beta(h) + Alpha-catulin(h) <==> IKK-beta(h):Alpha-catulin(h) (binding)
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IKK-beta(h) + Hsp50(h) <==> IKK-beta(h):Hsp50(h) (binding)
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Hsp90(h) + IKK-beta(h) <==> Hsp90(h):IKK-beta(h) (binding)
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CIKS(h) + IKK-beta(h) <==> CIKS(h):IKK-beta(h) (binding)
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IKBKB(h) --> IKK-beta(h) (expression).
|
RelA-p65(h) + ATP --IKK-beta(h)--> RelA-p65(h){pS468} + ADP (phosphorylation)
|
RelA-p65(h) + ATP --IKK-beta(h)--> RelA-p65(h){pS536} + ADP (phosphorylation)
|
RelA-p65(h) + 2 ATP --IKK-beta(h)--> RelA-p65(h){pS468}{pS536} + 2 ADP (phosphorylation)
|
IkappaB(m.s.) + ATP --IKK-beta(h)--> IkappaB(m.s.){p} + ADP (phosphorylation)
|
Hsp50(h) + ATP --IKK-beta(h)--> Hsp50(h){p} + ADP (phosphorylation)
|
IkappaB-alpha(m.s.) + ATP --IKK-beta(h)--> IkappaB-alpha(m.s.){p} + ADP (phosphorylation)
|
