| FRATide(h) + GSK3beta(h) <==> FRATide(h):GSK3beta(h) (binding)
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apc(h) + axin(m) + GSK3beta(h) <==> apc(h):axin(m):GSK3beta(h) (binding)
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axin(m) + beta-catenin(h) + GSK3beta(h) <==> axin(m):beta-catenin(h):GSK3beta(h) (binding)
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GSK3beta(h) + PS1(h) + Tau(h) <==> GSK3beta(h):PS1(h):Tau(h) (binding)
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apc(h) + axin(h) + beta-catenin(h) + GSK3beta(h) <==> apc(h):axin(h):beta-catenin(h):GSK3beta(h) (binding)
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GSK3beta(h) + NTP --AKT-1(h){pT308}{pS473}--> GSK3beta(h){pS9} + NDP (phosphorylation)
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PKAc(h) + GSK3beta(h) <==> PKAc(h):GSK3beta(h) (binding)
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PKAc(m) + GSK3beta(h) <==> PKAc(m):GSK3beta(h) (binding)
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tuberin(h) + GSK3beta(h) <==> tuberin(h):GSK3beta(h) (binding)
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axin(h) + GSK3beta(h) + PR65(h) + PP2ACalpha(h) + beta-catenin(h) <==> axin(h):beta-catenin(h):GSK3beta(h):PP2ACalpha(h):PR65(h) (binding)
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axin(h) + GSK3beta(h) <==> axin(h):GSK3beta(h) (binding)
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GSK3beta(h) + Frat1(h) <==> Frat1(h):GSK3beta(h) (binding)
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GSK3beta(h) + Frat1(m) <==> Frat1(m):GSK3beta(h) (binding)
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2 GSK3beta(h) <==> GSK3beta(h):GSK3beta(h) (binding)
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GSK3beta(h) + SNA(h) <==> GSK3beta(h):SNA(h) (binding)
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GSK3beta(h) --> AR(m.s.) (regulation of protein activity)
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GSK3beta(h) + 2 ATP --> GSK3beta(h){pS9}{pY216} + 2 ADP (phosphorylation)
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GSK3beta(h) + ATP --> GSK3beta(h){p} + ADP (phosphorylation)
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GSK3beta(h) + ATP --> GSK3beta(h){pS9} + ADP (phosphorylation)
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GSK3beta(h) --/ p53(h) (decrease of abundance)
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GSK3beta(h) --/ TP53(h) (transrepression)
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GSK3beta(h) + MEKK1(h) <==> GSK3beta(h):MEKK1(h) (binding)
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p53-isoform1(h) + GSK3beta(h) <==> p53-isoform1(h):GSK3beta(h) (binding)
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p53(h) + GSK3beta(h) <==> p53(h):GSK3beta(h) (binding)
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GSK3beta(h) --> Cytochrome C(h) (increase of abundance)
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E2F-1(m.s.) + GSK3beta(h) <==> E2F-1(m.s.):GSK3beta(h) (binding)
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NF-kappaB1(h) + GSK3beta(h) <==> NF-kappaB1(h):GSK3beta(h) (binding)
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RelA-p65(h) + GSK3beta(h) <==> RelA-p65(h):GSK3beta(h) (binding)
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GSK3beta(h) + NF-kappaB1(m.s.) <==> GSK3beta(h):NF-kappaB1(m.s.) (binding)
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GSK3beta(h) + Gemin-4(h) <==> GSK3beta(h):Gemin-4(h) (binding)
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HSKM-B(h) + GSK3beta(h) <==> HSKM-B(h):GSK3beta(h) (binding)
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GSK3beta(h) + Gemin-3(h) <==> GSK3beta(h):Gemin-3(h) (binding)
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GSK3beta(h) + STRAP(h) <==> GSK3beta(h):STRAP(h) (binding)
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GSK3beta(h) + GSKIP(h) <==> GSK3beta(h):GSKIP(h) (binding)
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GSK3beta(h) + Exportin-6(h) <==> GSK3beta(h):Exportin-6(h) (binding)
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GSK3beta(h) + DDX36(h) <==> GSK3beta(h):DDX36(h) (binding)
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GSK3beta(h) + RPF2(h) <==> GSK3beta(h):RPF2(h) (binding)
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GSK3beta(h) + SMN2(h) <==> GSK3beta(h):SMN2(h) (binding)
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GSK3beta(h) + IMP-1(h) <==> GSK3beta(h):IMP-1(h) (binding)
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GSK3beta(h) + SF3b1(h) <==> GSK3beta(h):SF3b1(h) (binding)
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GSK3beta(h) + U1-70K(h) <==> GSK3beta(h):U1-70K(h) (binding)
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GSK3beta(h) + EWS(h) <==> GSK3beta(h):EWS(h) (binding)
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GSK3beta(h) + ATP-citrate synthase(h) <==> GSK3beta(h):ATP-citrate synthase(h) (binding)
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GSK3beta(h) + beta-catenin(h) <==> GSK3beta(h):beta-catenin(h) (binding)
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Smad7(m.s.) + axin(m.s.) + GSK3beta(h) + beta-catenin(h) + apc(h) + CKI(h) <==> Smad7(m.s.):axin(m.s.):GSK3beta(h):beta-catenin(h):apc(h):CKI(h) (binding)
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ER-alpha(h) + GSK3beta(h) <==> ER-alpha(h):GSK3beta(h) (binding)
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GSK3beta(h) + ATP --> GSK3beta(h){pY216} + ADP (phosphorylation)
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GSK3B(h) --> GSK3beta(h) (expression).
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Dkk-1(h) --/ GSK3beta(h) (decrease of abundance)
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axin(h) + ATP --GSK3beta(h)--> axin(h){p} + ADP (phosphorylation)
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beta-catenin(h) + ATP --GSK3beta(h)--> beta-catenin(h){p} + ADP (phosphorylation)
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axin(m) + ATP --GSK3beta(h)--> axin(m){p} + ADP (phosphorylation)
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APC(x):axin(m) + ATP --GSK3beta(h)--> APC(x){p}:axin(m) + ADP (phosphorylation)
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beta-catenin(x) + ATP --GSK3beta(h)--> beta-catenin(x){p} + ADP (phosphorylation)
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Tau(h) --GSK3beta(h)--> Tau(h){p} (phosphorylation)
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HSF1(h){pS307} + ATP --GSK3beta(h)--> HSF1(h){pS307}{pS303} + ADP (phosphorylation)
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apc(h):axin(r) + ATP --GSK3beta(h)--> apc(h){p}:axin(r){p} + ADP (phosphorylation)
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axin(h):beta-catenin(h) + ATP --GSK3beta(h)--> axin(h):beta-catenin(h){pS33}{pS37}{pT41}:axin(h) + ADP (phosphorylation)
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SNA(h) + ATP --GSK3beta(h)--> SNA(h){pS97}{pS101}{pS}n + ADP (phosphorylation)
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RelA-p65(h) + ATP --GSK3beta(h)--> RelA-p65(h){pS468} + ADP (phosphorylation)
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Bcl-3(h) + 2 ATP --GSK3beta(h)--> Bcl-3(h){pS394}{pS398} + 2 ADP (phosphorylation)
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Bcl-3(h) + ATP --GSK3beta(h)--> Bcl-3(h){p} + ADP (phosphorylation)
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Synphilin-1(h) + ATP --GSK3beta(h)--> Synphilin-1(h){p} + ADP (phosphorylation)
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CRMP1(h) + ATP --GSK3beta(h)--> CRMP1(h){pT509} + ADP (phosphorylation)
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CRMP1(h) + ATP --GSK3beta(h)--> CRMP1(h){pT509} + ADP (phosphorylation)
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ER-alpha(h) + ATP --GSK3beta(h)--> ER-alpha(h){pS118} + ADP (phosphorylation)
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MEKK4(m.s.) + ATP --GSK3beta(h)--> MEKK4(m.s.){p} + ADP (phosphorylation)
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GSK3B(h) --> GSK3beta-1(h) (expression).
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GSK3B(h) --> GSK3beta-2(h) (expression).
|
