| TBK1(h) + IRF-3(h) <==> TBK1(h):IRF-3(h) (binding)
|
TRIF(h) + TBK1(h) <==> TRIF(h):TBK1(h) (binding)
|
TRIF(h){p} + TBK1(h) <==> TRIF(h){p}:TBK1(h) (binding)
|
TBK1(h) + TANK(h) + IKK-gamma(h) <==> TBK1(h):TANK(h):IKK-gamma(h) (binding)
|
TANK(h) + TBK1(h) <==> TANK(h):TBK1(h) (binding)
|
TANK(h) + TBK1(h) <==> TANK(h):TBK1(h) (binding)
|
TBK1(h) + ATP --> TBK1(h){p} + ADP (phosphorylation; automodification)
|
TBK1(h) + sike(h) <==> TBK1(h):sike(h) (binding)
|
TBK1(h) --> RIP(h) (increase of abundance)
|
TBK1(h) --> TBK1(h) (expression).
|
IFNalpha1(h) --> TBK1(h) (increase of abundance)
|
IRF-3(h) + ATP --TBK1(h)--> IRF-3(h){p} + ADP (phosphorylation)
|
IRF-7(h) + ATP --TBK1(h)--> IRF-7(h){p} + ADP (phosphorylation)
|
IkappaB-alpha(h) + NTP --TBK1(h)--> IkappaB-alpha(h){pS36} + NDP (phosphorylation)
|
IKK-beta(v.s.) + 2 ATP --TBK1(h)--> IKK-beta(v.s.){pS177}{pS181} + 2 ADP (phosphorylation)
|
IkappaB-beta(h) + ATP --TBK1(h)--> IkappaB-beta(h){pS23} + ADP (phosphorylation)
|
RelA-p65(m.s.) + ATP --TBK1(h)--> RelA-p65(m.s.){pS536} + ADP (phosphorylation)
|
IRF-3(m.s.) + ATP --TBK1(h)--> IRF-3(m.s.){p} + ADP (phosphorylation)
|
IRF-7(m.s.) + ATP --TBK1(h)--> IRF-7(m.s.){p} + ADP (phosphorylation)
|
HCV-NS3-1B(HCV1B) + TBK1(h) <==> HCV-NS3-1B(HCV1B):TBK1(h) (binding)
|
TBK1(h) + IRF-3(h) <==> TBK1(h):IRF-3(h) (binding)
|
TICAM(h) + TBK1(h) <==> TICAM(h):TBK1(h) (binding)
|
TBK1(h) + ATP --> TBK1(h){p} + ADP (phosphorylation; automodification)
|
TBK1(h) + TRIF(h) <==> TBK1(h):TRIF(h) (binding)
|
TBK1(h) --> IFNB1(h) (transactivation)
|
TBK1(h) --> TBK1(h) (expression).
|
HCV-NS3-1B(HCV1B) --/ TBK1(h) (inhibition)
|
HCV-NS3-1B(HCV1B):HCV-NS4A-1B(HCV1B) --/ TBK1(h) (inhibition)
|
c-Rel(m.s.) + ATP --TBK1(h)--> c-Rel(m.s.){p} + ADP (phosphorylation)
|
IRF-3(m.s.) + ATP --TBK1(h)--> IRF-3(m.s.){p} + ADP (phosphorylation)
|
IRF-7(m.s.) + ATP --TBK1(h)--> IRF-7(m.s.){p} + ADP (phosphorylation)
|
TANK(h) + ATP --TBK1(h)--> TANK(h){p} + ADP (phosphorylation)
|
