| phlpp1(h) + PKCbetaII(m.s.) <==> phlpp1(h):PKCbetaII(m.s.) (binding)
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PHLPP(h) --> phlpp1(h) (expression).
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PKCbetaII(m.s.){pT641}{pS660} --phlpp1(h)--> PKCbetaII(m.s.) + 2 p (dephosphorylation)
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PKCbetaII(m.s.){p} --phlpp1(h)--> PKCbetaII(m.s.) + p (dephosphorylation)
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phlpp1(h) --> AKT-2(h){pS474} (increase of phosphorylation)
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phlpp1(h) --> AKT-3(h){p} (increase of phosphorylation)
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phlpp1(h) --/ PKCbeta(h) (decrease of abundance)
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phlpp1(h) --/ PKCalpha(h) (decrease of abundance)
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phlpp1(h) --/ PKCdelta(h) (decrease of abundance)
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phlpp1(h) --/ PKCepsilon(h) (decrease of abundance)
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PHLPP(h) --> phlpp1(h) (expression).
|
Abl(h) --/ phlpp1(h) (decrease of abundance)
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