| ERK1(ha) + MKP-1(h) <==> ERK1(ha):MKP-1(h) (binding)
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ERK2(m) + MKP-1(h) <==> ERK2(m):MKP-1(h) (binding)
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JNK1(h) + MKP-1(h) <==> JNK1(h):MKP-1(h) (binding)
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p38alpha(m) + MKP-1(h) <==> p38alpha(m):MKP-1(h) (binding)
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MKP-1(h) + SPI1(m.s.) <==> MKP-1(h):SPI1(m.s.) (binding)
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MKP-1(h) + p38alpha(m.s.) <==> MKP-1(h):p38alpha(m.s.) (binding)
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ERK2(h) + MKP-1(h) <==> ERK2(h):MKP-1(h) (binding)
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MKP-1(h) --> ERK(h){p} (decrease of phosphorylation)
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MKP-1(h) + 2 ATP --> MKP-1(h){pS359}{pS364} + 2 ADP (phosphorylation)
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DUSP1(h) --> MKP-1(h) (expression).
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angiotensin II(m.s.) --> MKP-1(h) (increase of abundance)
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Jak2(m) --> MKP-1(h) (increase of abundance)
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BTEB2(h) --> MKP-1(h) (increase of abundance)
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FGF-BP(h) --> MKP-1(h) (increase of abundance)
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ERK2(v.s.){p} --MKP-1(h)--> ERK2(v.s.) + p (dephosphorylation)
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ERK1(h){p} --MKP-1(h)--> ERK1(h) + p (dephosphorylation)
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p38alpha(m) + ATP --MKK4(m){p}--> p38alpha(m){p} + ADP (phosphorylation)
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p38alpha(m) + ATP --MKK3(h){p}--> p38alpha(m){p} + ADP (phosphorylation)
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p38alpha(m) + ATP --MKK6(h){p}--> p38alpha(m){p} + ADP (phosphorylation)
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p53(m) + ATP --JNK1(h){p}--> p53(m){pS34} + ADP (phosphorylation)
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MBP(v.s.) + ATP --ERK2(m){p}--> MBP(v.s.){p} + ADP (phosphorylation)
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ATF-2(v.s.) + ATP --JNK1(h){p}--> ATF-2(v.s.){p} + ADP (phosphorylation)
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DUSP1(h) --> MKP-1(h) (expression).
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