| Cot(h) + NIK(h) <==> Cot(h):NIK(h) (binding)
|
Cot(h) --> IKK-alpha(m) (activation)
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TRAF2(m) + Cot(h) <==> TRAF2(m):Cot(h) (binding)
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Cot(h) + NF-kappaB1(h) <==> Cot(h):NF-kappaB1(h) (binding)
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NF-kappaB1-p50(h):NF-kappaB1(h):RelA-p65(h) + Cot(h) <==> NF-kappaB1-p50(h):NF-kappaB1(h):RelA-p65(h):Cot(h) (binding)
|
NF-kappaB1-p50(h):NF-kappaB1(h):c-Rel(h) + Cot(h) <==> NF-kappaB1-p50(h):NF-kappaB1(h):c-Rel(h):Cot(h) (binding)
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AKT(b) + Cot(h) <==> AKT(b):Cot(h) (binding)
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Cot(h) + ATP --> Cot(h){p} + ADP (phosphorylation)
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NF-kappaB1-isoform2(h) + Cot(h) <==> NF-kappaB1-isoform2(h):Cot(h) (binding)
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MAP3K8(h) --> Cot(h) (expression).
|
MKK6(h) + ATP --Cot(h)--> MKK6(h){p} + ADP (phosphorylation)
|
MKK4(m) + ATP --Cot(h)--> MKK4(m){p} + ADP (phosphorylation)
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Cot-58kDa(h) + ATP --> Cot-58kDa(h){pS62} + ADP (phosphorylation)
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Cot-58kDa(h) + 2 ATP --> Cot-58kDa(h){pS62}{pT290} + 2 ADP (phosphorylation)
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MAP3K8(h) --> Cot-58kDa(h) (expression).
|
MAP3K8(h) --> Cot-52kDa(h) (expression).
|
