| Tob1(h) + ATP --ERK2(x)--> Tob1(h){p} + ADP (phosphorylation)
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Tob1(h) + ATP --JNK2(r)--> Tob1(h){p} + ADP (phosphorylation)
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ERK2(x) + Tob1(h) <==> ERK2(x):Tob1(h) (binding)
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JNK2(r) + Tob1(h) <==> JNK2(r):Tob1(h) (binding)
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brca1(m.s.) + Tob1(h) <==> brca1(m.s.):Tob1(h) (binding)
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Tob1(h) --/ cyclinD1(h) (decrease of abundance)
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Tob1(h) --/ cyclinA(h) (decrease of abundance)
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Tob1(h) + Skp2(h) <==> Tob1(h):Skp2(h) (binding)
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Tob1(h) --> protein remnants (degradation)
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TOB1(h) --> Tob1(h) (expression).
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Skp2-xbb1(m) + Tob1(h) <==> Skp2-xbb1(m):Tob1(h) (binding)
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Tob1(h) + ATP --ERK1(m.s.)--> Tob1(h){pS152}{pS154} + ADP (phosphorylation)
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Skp2(m.s.) + Tob1(h) <==> Skp2(m.s.):Tob1(h) (binding)
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Tob1(h) + n ubiquitin(h) --Skp2-xbb1(m)--> Tob1(h){ub}n (ubiquitination)
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Tob1(h) + ubiquitin(h) --E1(m.s.),Cdc34(h),Skp2-xbb1(m)--> Tob1(h){ub}n (ubiquitination)
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Tob1(h) + n ubiquitin(h) --E1(m.s.),Ubc5B(h),Skp2-xbb1(m)--> Tob1(h){ub}n (ubiquitination)
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TOB1(h) --> Tob1(h) (expression).
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