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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

8754

Name

ADAM9

Synonymous

ADAM metallopeptidase domain 9;ADAM9;ADAM metallopeptidase domain 9

Definition

ADAM metallopeptidase domain 9 (meltrin gamma)|cellular disintegrin-related protein|cone rod dystrophy 9|disintegrin and metalloproteinase domain-containing protein 9|metalloprotease/disintegrin/cysteine-rich protein 9|myeloma cell metalloproteinase

Position

8p11.22

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1158T>A; p.S386R; 8:39041973-39041973

 breastcarcinomaSubstitution - Missense

c.1543G>A; p.G515S; 8:39055724-39055724

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.1439G>T; p.C480F; 8:39055620-39055620

 breastcarcinomaSubstitution - Missense

c.2412T>A; p.I804I; 8:39103652-39103652

 breastcarcinomaSubstitution - coding silent

c.604C>T; p.R202*; 8:39017412-39017412

 central_nervous_system; medullaprimitive_neuroectodermal_tumour-medulloblastoma; classicSubstitution - Nonsense

c.351G>A; p.R117R; 8:39016135-39016135

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.351G>A; p.R117R; 8:39016135-39016135

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1956A>G; p.G652G; 8:39082715-39082715

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.605G>A; p.R202Q; 8:39017413-39017413

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.412G>T; p.G138*; 8:39017220-39017220

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.108G>T; p.Q36H; 8:39007896-39007896

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1451A>G; p.E484G; 8:39055632-39055632

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2347C>T; p.P783S; 8:39101911-39101911

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1854C>T; p.N618N; 8:39077384-39077384

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1814T>C; p.F605S; 8:39077344-39077344

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.767G>A; p.R256Q; 8:39023178-39023178

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.767G>A; p.R256Q; 8:39023178-39023178

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.767G>A; p.R256Q; 8:39023178-39023178

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2249C>T; p.P750L; 8:39091297-39091297

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1387G>T; p.D463Y; 8:39054565-39054565

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.1566T>C; p.A522A; 8:39055747-39055747

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.1288T>A; p.C430S; 8:39042103-39042103

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.711A>T; p.E237D; 8:39021681-39021681

 kidneyother; neoplasmSubstitution - Missense

c.247A>T; p.R83W; 8:39011709-39011709

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.2293G>T; p.E765*; 8:39091341-39091341

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1092C>T; p.S364S; 8:39026772-39026772

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1188T>A; p.N396K; 8:39042003-39042003

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.862_863insG; p.E289fs*11; 8:39023273-39023274

 large_intestine; caecumcarcinoma; adenocarcinomaInsertion - Frameshift

c.2174G>T; p.R725I; 8:39090152-39090152

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.220G>T; p.G74*; 8:39011682-39011682

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.2451C>A; p.S817S; 8:39103691-39103691

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.853G>A; p.V285M; 8:39023264-39023264

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1633T>C; p.S545P; 8:39071339-39071339

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.659T>C; p.V220A; 8:39018905-39018905

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.260delT; p.L88fs*16; 8:39013970-39013970

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.2195G>A; p.R732K; 8:39090173-39090173

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.471delT; p.F158fs*16; 8:39017279-39017279

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.235A>G; p.I79V; 8:39011697-39011697

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.681G>A; p.M227I; 8:39021651-39021651

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.164G>T; p.R55I; 8:39007952-39007952

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.491G>A; p.R164Q; 8:39017299-39017299

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.491G>A; p.R164Q; 8:39017299-39017299

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1787G>A; p.R596Q; 8:39077317-39077317

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.2186G>T; p.R729I; 8:39090164-39090164

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.131A>C; p.E44A; 8:39007919-39007919

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1420C>T; p.R474*; 8:39055601-39055601

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.7T>C; p.S3P; 8:38997070-38997070

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.7T>C; p.S3P; 8:38997070-38997070

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.2092G>A; p.G698R; 8:39090070-39090070

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1620C>T; p.F540F; 8:39071326-39071326

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1789G>T; p.G597C; 8:39077319-39077319

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1635T>C; p.S545S; 8:39071341-39071341

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1152T>C; p.S384S; 8:39041967-39041967

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.767G>A; p.R256Q; 8:39023178-39023178

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.2136T>C; p.C712C; 8:39090114-39090114

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2433A>G; p.A811A; 8:39103673-39103673

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.862C>T; p.R288W; 8:39023273-39023273

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1130+1G>A; p.?; 8:39026811-39026811

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.2073G>C; p.M691I; 8:39090051-39090051

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1055A>C; p.N352T; 8:39026735-39026735

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1790G>A; p.G597D; 8:39077320-39077320

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1778C>T; p.T593M; 8:39077308-39077308

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2367-8C>T; p.?; 8:39103599-39103599

 livercarcinomaUnknown

c.95C>T; p.P32L; 8:38997158-38997158

 livercarcinomaSubstitution - Missense

c.95C>T; p.P32L; 8:38997158-38997158

 livercarcinomaSubstitution - Missense

c.460A>T; p.N154Y; 8:39017268-39017268

 livercarcinomaSubstitution - Missense

c.460A>T; p.N154Y; 8:39017268-39017268

 livercarcinomaSubstitution - Missense

c.1735C>T; p.Q579*; 8:39077265-39077265

 livercarcinoma; hepatocellular_carcinomaSubstitution - Nonsense

c.1319C>T; p.P440L; 8:39054497-39054497

 livercarcinomaSubstitution - Missense

c.1319C>T; p.P440L; 8:39054497-39054497

 livercarcinomaSubstitution - Missense

c.1319C>T; p.P440L; 8:39054497-39054497

 livercarcinomaSubstitution - Missense

c.1319C>T; p.P440L; 8:39054497-39054497

 livercarcinomaSubstitution - Missense

c.546A>G; p.I182M; 8:39017354-39017354

 livercarcinomaSubstitution - Missense

c.2366+3C>T; p.?; 8:39101933-39101933

 lungcarcinoma; small_cell_carcinomaUnknown

c.795G>C; p.W265C; 8:39023206-39023206

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1049G>T; p.G350V; 8:39026729-39026729

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1382G>T; p.C461F; 8:39054560-39054560

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1162G>T; p.E388*; 8:39041977-39041977

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Nonsense

c.312C>G; p.I104M; 8:39014022-39014022

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.782G>C; p.G261A; 8:39023193-39023193

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2420G>A; p.R807H; 8:39103660-39103660

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1905A>T; p.V635V; 8:39082664-39082664

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1327G>T; p.E443*; 8:39054505-39054505

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.2295A>G; p.E765E; 8:39091343-39091343

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.888G>C; p.R296R; 8:39023299-39023299

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1529C>A; p.A510D; 8:39055710-39055710

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1423G>A; p.G475R; 8:39055604-39055604

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1361A>T; p.E454V; 8:39054539-39054539

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.2369C>T; p.P790L; 8:39103609-39103609

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1071C>G; p.H357Q; 8:39026751-39026751

 ovaryother; neoplasmSubstitution - Missense

c.1634C>A; p.S545Y; 8:39071340-39071340

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.2210+5T>G; p.?; 8:39090193-39090193

 pancreascarcinomaUnknown

c.434C>T; p.A145V; 8:39017242-39017242

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.794G>A; p.W265*; 8:39023205-39023205

 prostatecarcinoma; adenocarcinomaSubstitution - Nonsense

c.1200C>A; p.N400K; 8:39042015-39042015

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.810G>A; p.L270L; 8:39023221-39023221

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.2008_2009CC>TT; p.P670F; 8:39083013-39083014

 skin; facecarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.452C>T; p.P151L; 8:39017260-39017260

 skinmalignant_melanomaSubstitution - Missense

c.2236C>T; p.P746S; 8:39091284-39091284

 skin; upper_armmalignant_melanomaSubstitution - Missense

c.1243C>T; p.P415S; 8:39042058-39042058

 skinmalignant_melanomaSubstitution - Missense

c.1243C>T; p.P415S; 8:39042058-39042058

 skinmalignant_melanomaSubstitution - Missense

c.724C>T; p.L242L; 8:39021694-39021694

 skinmalignant_melanomaSubstitution - coding silent

c.813C>T; p.I271I; 8:39023224-39023224

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1398C>T; p.F466F; 8:39055579-39055579

 skinmalignant_melanomaSubstitution - coding silent

c.1151G>A; p.S384N; 8:39041966-39041966

 skinmalignant_melanomaSubstitution - Missense

c.2109C>T; p.F703F; 8:39090087-39090087

 skinmalignant_melanomaSubstitution - coding silent

c.2263C>T; p.R755*; 8:39091311-39091311

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.2276C>T; p.P759L; 8:39091324-39091324

 skinmalignant_melanomaSubstitution - Missense

c.2372C>T; p.P791L; 8:39103612-39103612

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1247C>T; p.S416F; 8:39042062-39042062

 skinmalignant_melanomaSubstitution - Missense

c.532T>C; p.S178P; 8:39017340-39017340

 skin; mucosalmalignant_melanomaSubstitution - Missense

c.987G>A; p.G329G; 8:39025875-39025875

 skinmalignant_melanomaSubstitution - coding silent

c.37C>T; p.R13C; 8:38997100-38997100

 skinmalignant_melanomaSubstitution - Missense

c.775C>T; p.L259L; 8:39023186-39023186

 skinmalignant_melanomaSubstitution - coding silent

c.545T>A; p.I182K; 8:39017353-39017353

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.178A>T; p.R60W; 8:39007966-39007966

 skinmalignant_melanomaSubstitution - Missense

c.2134T>G; p.C712G; 8:39090112-39090112

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1184delT; p.L395fs*1; 8:39041999-39041999

 soft_tissue; striated_musclerhabdomyosarcomaDeletion - Frameshift

c.1410T>C; p.G470G; 8:39055591-39055591

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1339T>C; p.C447R; 8:39054517-39054517

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1779G>A; p.T593T; 8:39077309-39077309

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1393C>T; p.R465W; 8:39054571-39054571

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.349C>T; p.R117W; 8:39016133-39016133

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.480C>T; p.H160H; 8:39017288-39017288

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1244C>T; p.P415L; 8:39042059-39042059

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1390T>A; p.C464S; 8:39054568-39054568

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1323C>A; p.C441*; 8:39054501-39054501

 urinary_tract; bladdercarcinomaSubstitution - Nonsense

c.1323C>A; p.C441*; 8:39054501-39054501

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Nonsense

c.573G>T; p.E191D; 8:39017381-39017381

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.573G>T; p.E191D; 8:39017381-39017381

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.2227C>G; p.Q743E; 8:39091275-39091275

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1637A>G; p.K546R; 8:39071343-39071343

 urinary_tract; bladdercarcinomaSubstitution - Missense