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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

11279

Name

KLF8

Synonymous

Kruppel-like factor 8;KLF8;Kruppel-like factor 8

Definition

Krueppel-like factor 8|basic krueppel-like factor 3|basic kruppel-like factor 3|zinc finger protein 741

Position

Xp11.21

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.640G>T; p.G214*; 23:56265738-56265738

 breastcarcinomaSubstitution - Nonsense

c.458G>T; p.S153I; 23:56265556-56265556

 breastcarcinomaSubstitution - Missense

c.371C>A; p.T124K; 23:56265469-56265469

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.371C>A; p.T124K; 23:56265469-56265469

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.858C>A; p.T286T; 23:56270281-56270281

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1060C>T; p.R354C; 23:56284474-56284474

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.699G>T; p.E233D; 23:56269430-56269430

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.335A>G; p.K112R; 23:56265433-56265433

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.82G>A; p.V28I; 23:56265180-56265180

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.92C>A; p.S31Y; 23:56265190-56265190

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.10A>G; p.M4V; 23:56250233-56250233

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.976C>T; p.R326C; 23:56284390-56284390

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.685C>A; p.P229T; 23:56269416-56269416

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.861A>C; p.K287N; 23:56270284-56270284

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.614T>G; p.L205R; 23:56265712-56265712

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.541G>C; p.V181L; 23:56265639-56265639

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.655G>C; p.D219H; 23:56269386-56269386

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1061G>A; p.R354H; 23:56284475-56284475

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.909T>G; p.P303P; 23:56284323-56284323

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.486T>C; p.T162T; 23:56265584-56265584

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.560T>C; p.M187T; 23:56265658-56265658

 kidneycarcinoma; renal_cell_carcinomaSubstitution - Missense

c.94G>T; p.V32F; 23:56265192-56265192

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.950G>A; p.R317H; 23:56284364-56284364

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1061G>A; p.R354H; 23:56284475-56284475

 large_intestine; colonNSSubstitution - Missense

c.372G>A; p.T124T; 23:56265470-56265470

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1022G>A; p.R341H; 23:56284436-56284436

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.795G>A; p.S265S; 23:56270218-56270218

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1047G>C; p.L349L; 23:56284461-56284461

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1015T>A; p.C339S; 23:56284429-56284429

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.832T>G; p.F278V; 23:56270255-56270255

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.994A>G; p.K332E; 23:56284408-56284408

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.772G>A; p.A258T; 23:56270195-56270195

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1039G>C; p.D347H; 23:56284453-56284453

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.766G>A; p.A256T; 23:56270189-56270189

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1034G>A; p.R345H; 23:56284448-56284448

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.7G>A; p.D3N; 23:56233341-56233341

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.547C>T; p.Q183*; 23:56265645-56265645

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1054C>T; p.H352Y; 23:56284468-56284468

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1064G>A; p.R355H; 23:56284478-56284478

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.421C>A; p.P141T; 23:56265519-56265519

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.310C>A; p.L104I; 23:56265408-56265408

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.434T>C; p.L145P; 23:56265532-56265532

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.386T>C; p.M129T; 23:56265484-56265484

 livercarcinomaSubstitution - Missense

c.702G>C; p.E234D; 23:56269433-56269433

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.823C>A; p.Q275K; 23:56270246-56270246

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.781C>A; p.Q261K; 23:56270204-56270204

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1021C>A; p.R341S; 23:56284435-56284435

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.102C>G; p.N34K; 23:56265200-56265200

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.191A>T; p.N64I; 23:56265289-56265289

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.917G>T; p.C306F; 23:56284331-56284331

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.310C>A; p.L104I; 23:56265408-56265408

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.596C>A; p.A199E; 23:56265694-56265694

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.761C>G; p.P254R; 23:56270184-56270184

 oesophaguscarcinomaSubstitution - Missense

c.181G>A; p.A61T; 23:56265279-56265279

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.217G>A; p.E73K; 23:56265315-56265315

 salivary_gland; parotidcarcinoma; adenoid_cystic_carcinomaSubstitution - Missense

c.109C>T; p.P37S; 23:56265207-56265207

 skinmalignant_melanomaSubstitution - Missense

c.109C>T; p.P37S; 23:56265207-56265207

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.157G>A; p.D53N; 23:56265255-56265255

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1003C>T; p.R335W; 23:56284417-56284417

 skinmalignant_melanomaSubstitution - Missense

c.235T>C; p.F79L; 23:56265333-56265333

 skinmalignant_melanomaSubstitution - Missense

c.854A>G; p.Y285C; 23:56270277-56270277

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.326G>A; p.R109H; 23:56265424-56265424

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.37G>A; p.V13I; 23:56250260-56250260

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.664T>C; p.S222P; 23:56269395-56269395

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.359delT; p.V121fs*9; 23:56265457-56265457

 stomachadenocarcinomaDeletion - Frameshift

c.468C>G; p.I156M; 23:56265566-56265566

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense