| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 9126 |
Name | SMC3 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for SMC3 |
| Links to the AnimalTFDB for SMC3 |
Regulation From TransFac database | SMC3(h) --> SMC-3(h) (expression). | SMC1(h) + SMC-3(h) <==> SMC1(h):SMC-3(h) (binding) | Wapl(h) + Pds5B(h) + Pds5A(h) + SMC-3(h) + SMC1(h) + Rad21(h) + SA-2(h) + SA-1(h) <==> Wapl(h):Pds5B(h):Pds5A(h):SMC-3(h):SMC1(h):Rad21(h):SA-2(h):SA-1(h) (binding) | Pds5B(h) + Pds5A(h) + SA-2(h) + SMC-3(h) + Rad21(h) + Wapl(h) <==> Pds5B(h):Pds5A(h):SA-2(h):SMC-3(h):Rad21(h):Wapl(h) (binding) | SMC-3(h) + SMC1(h) + Rad21(h) + SA-1(h) + SA-2(h) + Pds5A(h) + Pds5B(h) + Wapl(h) + Sororin(h) <==> SMC-3(h):SMC1(h):Rad21(h):SA-1(h):SA-2(h):Pds5A(h):Pds5B(h):Wapl(h):Sororin(h) (binding) | Pds5B(h) + SMC1(h) + SMC-3(h) + Rad21(h) + Sororin(h) <==> Pds5B(h):SMC1(h):SMC-3(h):Rad21(h):Sororin(h) (binding) | SMC-3(h) + SMC1(h) + Pds5B(h) + Pds5A(h) + Sororin(m.s.) <==> SMC-3(h):SMC1(h):Pds5B(h):Pds5A(h):Sororin(m.s.) (binding) | Rad21(h) + SMC-3(h) + Pds5B(h) + Pds5A(h) + Sororin(m.s.) <==> Rad21(h):SMC-3(h):Pds5B(h):Pds5A(h):Sororin(m.s.) (binding) | Rad21(h) + SMC-3(h) + Sororin(m.s.) <==> Rad21(h):SMC-3(h):Sororin(m.s.) (binding) | Rad21(h) + SMC-3(h) + Wapl(h) <==> Rad21(h):SMC-3(h):Wapl(h) (binding) | SMC-3(h) + ATP --> SMC-3(h){pS1067} + ADP (phosphorylation) | SMC-3(h) + numa1(h) <==> SMC-3(h):numa1(h) (binding) | SMC-3(h) + Dynein(h) <==> SMC-3(h):Dynein(h) (binding) | SMC-3(h) + beta-tubulin(h) <==> SMC-3(h):beta-tubulin(h) (binding) | SMC1(h) + SMC-3(h) + Rad21(h) + SA-1(h) <==> SMC1(h):SMC-3(h):Rad21(h):SA-1(h) (binding) | SMC1(h) + SMC-3(h) + Rad21(h) + SA-2(h) <==> SMC1(h):SMC-3(h):Rad21(h):SA-2(h) (binding) | SRp55(h) + SRp75(h) + SRm300(h) + Rad21(h) + SMC-3(h) + SMC1(h) + SRm160(h) <==> SRp55(h):SRp75(h):SRm300(h):Rad21(h):SMC-3(h):SMC1(h):SRm160(h) (binding) | Ku70(h) + Ccte(h) + Pds5A(h) + PPIL1(h) + eIF-3gamma(h) + SAFB1(h) + Wapl(h) + Rad21(h) + SMC-3(h) + SMC1(h) + CAPER-alpha(h) + CNOT3(h) + NCoA-5(h) + SIAHBP1(h) + FBP(h) + HYPA(h) + SKIP(h) + SRm300(h) + SRm160(h) + p54nrb/NonO(h) + rbm25(h) + rbm8A(h) + Pinin(h) + Prp19(h) + cdc5L(h) + Snrp116(h) + Prpf8(h) + Sf3b-4(h) + Sf3b-2(h) + hnRNPM(h) + hnRNP-G(h) <==> Ku70(h):Ccte(h):Pds5A(h):PPIL1(h):eIF-3gamma(h):SAFB1(h):Wapl(h):Rad21(h):SMC-3(h):SMC1(h):CAPER-alpha(h):CNOT3(h):NCoA-5(h):SIAHBP1(h):FBP(h):HYPA(h):SKIP(h):SRm300(h):SRm160(h):p54nrb/NonO(h):rbm25(h):rbm8A(h):Pinin(h):Prp19(h):cdc5L(h):Snrp116(h):Prpf8(h):Sf3b-4(h):Sf3b-2(h):hnRNPM(h):hnRNP-G(h) (binding) | Rad21(h) + SMC-3(h) + SMC1(h) + CHLR1(h) <==> Rad21(h):SMC-3(h):SMC1(h):CHLR1(h) (binding) | Caspase-4(h) + SMC-3(h) <==> Caspase-4(h):SMC-3(h) (binding) | NEK6(h) + SMC-3(h) <==> NEK6(h):SMC-3(h) (binding) | Cdk4(h) + SMC-3(h) <==> Cdk4(h):SMC-3(h) (binding) | NRAGE(h) + SMC-3(h) <==> NRAGE(h):SMC-3(h) (binding) | SMC3(h) --> SMC-3(h) (expression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 1013 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 1065 | Phosphoserine. | Swiss-Prot 53.0 | 1067 | Phosphoserine. | Swiss-Prot 53.0 | 1074 | Phosphoserine. | Swiss-Prot 53.0 | 1083 | Phosphoserine. | Swiss-Prot 53.0 | 1074 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 1083 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 1065 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 1067 | Phosphoserine | 15302935 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr10 |
Promoter: 112315939 - 112317939 | GSE27584 |
chr10 |
Promoter: 112315939 - 112317939 | Agilent_014791_44K |