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General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information
Gene ID	8650
Name	NUMB
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget
Transcription factors [Top]
Links to the hTFtarget for NUMB
Links to the AnimalTFDB for NUMB
Regulation From TransFac database
LNX-1(m) + Numb(h) <==> LNX-1(m):Numb(h) (binding)
Numb(h) + ubiquitin(h) --LNX-1(m)--> Numb(h){ub} (ubiquitination)
Numb(h) + Siah1(h) <==> Numb(h):Siah1(h) (binding)
mdm2(m) + Numb(h) <==> mdm2(m):Numb(h) (binding)
Numb(h) + RIP1(h) <==> Numb(h):RIP1(h) (binding)
ErbB1-p170(h){pY1016} + Numb(h) <==> ErbB1-p170(h){pY1016}:Numb(h) (binding)
brca1(m.s.) + Numb(h) <==> brca1(m.s.):Numb(h) (binding)
Numb(h) + P-selectin(h) <==> Numb(h):P-selectin(h) (binding)
NUMB(h) --> Numb(h) (expression).
NUMB(h) --> Numb-isoform1(h) (expression).
NUMB(h) --> Numb-isoform2(h) (expression).
Numb-isoform3(h) + P-selectin(m.s.) <==> Numb-isoform3(h):P-selectin(m.s.) (binding)
NUMB(h) --> Numb-isoform3(h) (expression).
CRMP2(h) + Numb-isoform4(h) <==> CRMP2(h):Numb-isoform4(h) (binding)
CRMP2(r) + Numb-isoform4(h) <==> CRMP2(r):Numb-isoform4(h) (binding)
alpha-adaptin(r) + Numb-isoform4(h) <==> alpha-adaptin(r):Numb-isoform4(h) (binding)
NUMB(h) --> Numb-isoform4(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
276	Phosphoserine.		Swiss-Prot 53.0
295	Phosphoserine.		Swiss-Prot 53.0
631	Phosphothreonine (By similarity).		Swiss-Prot 53.0
634	Phosphoserine.		Swiss-Prot 53.0
438	Phosphoserine	17081983	Phospho.ELM 6.0

Chromosome	Location	Source
Methylation Profile [Top]
chr14	Promoter: 72994539 - 72996539	Agilent_014791
chr14	Promoter: 72994539 - 72996539	GSE27584
chr14	Promoter: 72994539 - 72996539	GSE27584
chr14	Promoter: 72994539 - 72996539	GSE27584
chr14	Promoter: 72994539 - 72996539	GSE27584
chr14	Promoter: 72994539 - 72996539	Agilent_014791_44K
chr14	Promoter: 72994539 - 72996539	Agilent_014791_44K
chr14	Promoter: 72994539 - 72996539	Agilent_014791_44K
chr14	Promoter: 72994539 - 72996539	Agilent_014791_44K

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