Entrez Gene

Basic Information
Gene ID	7534
Name	YWHAZ
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget
Transcription factors [Top]
Links to the hTFtarget for YWHAZ
Links to the AnimalTFDB for YWHAZ
Regulation From TransFac database
FOXO3a(h){pS294}{pS344}{pS425} + 14-3-3zeta(h) <==> FOXO3a(h){pS294}{pS344}{pS425}:14-3-3zeta(h) (binding)
ASK1(h){pS967} + 14-3-3zeta(h) <==> ASK1(h){pS967}:14-3-3zeta(h) (binding)
FOXO3a(h) + 14-3-3zeta(h) <==> FOXO3a(h):14-3-3zeta(h) (binding).
A20(h) + 14-3-3zeta(h) <==> A20(h):14-3-3zeta(h) (binding)
14-3-3zeta(h) + Raf-1(h) <==> 14-3-3zeta(h):Raf-1(h) (binding)
14-3-3zeta(h) + Raf-1(h){pS} <==> 14-3-3zeta(h):Raf-1(h){pS} (binding)
14-3-3zeta(h) + PFK2-isoform1(h){pS466}{pS483} <==> PFK2-isoform1(h){pS466}{pS483}:14-3-3zeta(h) (binding)
14-3-3zeta(h) + tuberin(h) <==> 14-3-3zeta(h):tuberin(h) (binding)
Tau(h) + 14-3-3zeta(h) <==> Tau(h):14-3-3zeta(h) (binding)
14-3-3zeta(h) + tuberin(h){p} <==> 14-3-3zeta(h):tuberin(h){p} (binding)
14-3-3zeta(h) + Bax(h) <==> 14-3-3zeta(h):Bax(h) (binding)
2 14-3-3zeta(h) + foxo4(h){pT28}{pS193}{pS258} <==> (14-3-3zeta(h))2:foxo4(h){pT28}{pS193}{pS258} (binding)
14-3-3zeta(h) + IGF-1R-beta(m.s.) <==> 14-3-3zeta(h):IGF-1R-beta(m.s.) (binding)
MGMT(h) + 14-3-3zeta(h) <==> MGMT(h):14-3-3zeta(h) (binding)
14-3-3zeta(h) + kif5b(h) <==> 14-3-3zeta(h):kif5b(h) (binding)
14-3-3zeta(h) + larp1(h) <==> 14-3-3zeta(h):larp1(h) (binding)
14-3-3zeta(h) + SAMD4B(h) <==> 14-3-3zeta(h):SAMD4B(h) (binding)
14-3-3zeta(h) + epb41l3(h) <==> 14-3-3zeta(h):epb41l3(h) (binding)
14-3-3zeta(h) + UBPY(h) <==> 14-3-3zeta(h):UBPY(h) (binding)
14-3-3zeta(h) + ICAD(h) <==> 14-3-3zeta(h):ICAD(h) (binding)
14-3-3zeta(h) + B-Raf(h) <==> 14-3-3zeta(h):B-Raf(h) (binding)
14-3-3zeta(h) + KNS2(h) <==> 14-3-3zeta(h):KNS2(h) (binding)
14-3-3zeta(h) + PAK4(h) <==> 14-3-3zeta(h):PAK4(h) (binding)
14-3-3zeta(h) + tjp2(h) <==> 14-3-3zeta(h):tjp2(h) (binding)
14-3-3zeta(h) + Sfrs10(h) <==> 14-3-3zeta(h):Sfrs10(h) (binding)
14-3-3zeta(h) + Nopp140(h) <==> 14-3-3zeta(h):Nopp140(h) (binding)
14-3-3zeta(h) + NORPEG(h) <==> 14-3-3zeta(h):NORPEG(h) (binding)
14-3-3zeta(h) + ralgps2(h) <==> 14-3-3zeta(h):ralgps2(h) (binding)
14-3-3zeta(h) + LSM16(h) <==> 14-3-3zeta(h):LSM16(h) (binding)
14-3-3zeta(h) + C22orf9(h) <==> 14-3-3zeta(h):C22orf9(h) (binding)
14-3-3zeta(h) + KNSL8(h) <==> 14-3-3zeta(h):KNSL8(h) (binding)
14-3-3zeta(h) + NAD kinase(h) <==> 14-3-3zeta(h):NAD kinase(h) (binding)
14-3-3zeta(h) + c-Met(h) <==> 14-3-3zeta(h):c-Met(h) (binding)
14-3-3zeta(h) + rpl31(h) <==> 14-3-3zeta(h):rpl31(h) (binding)
14-3-3zeta(h) + NAP1(h) <==> 14-3-3zeta(h):NAP1(h) (binding)
14-3-3zeta(h) + APP1(h) <==> 14-3-3zeta(h):APP1(h) (binding)
14-3-3zeta(h) + SF3b1(h) <==> 14-3-3zeta(h):SF3b1(h) (binding)
14-3-3zeta(h) + POB1(h) <==> 14-3-3zeta(h):POB1(h) (binding)
14-3-3zeta(h) + NOXA1-isoform1(h){pS172}{pS461} <==> 14-3-3zeta(h):NOXA1-isoform1(h){pS172}{pS461} (binding)
14-3-3zeta(h) + NOXA1(h) <==> 14-3-3zeta(h):NOXA1(h) (binding)
14-3-3zeta(h) + Ku70(h) <==> 14-3-3zeta(h):Ku70(h) (binding)
QSK(h){pT} + 14-3-3zeta(h) <==> QSK(h){pT}:14-3-3zeta(h) (binding)
14-3-3epsilon(h) + 14-3-3zeta(h) + alpha-tubulin 1B(h) + Hsp70-1(h) + QSK(h) <==> 14-3-3epsilon(h):14-3-3zeta(h):alpha-tubulin 1B(h):Hsp70-1(h):QSK(h) (binding)
14-3-3epsilon(h) + 14-3-3zeta(h) + alpha-tubulin 1B(h) + Hsp70-1(h) + SIK(h) <==> 14-3-3epsilon(h):14-3-3zeta(h):alpha-tubulin 1B(h):Hsp70-1(h):SIK(h) (binding)
14-3-3epsilon(h) + 14-3-3zeta(h) + alpha-tubulin 1B(h) + Hsp70-1(h) + mark1(h) <==> 14-3-3epsilon(h):14-3-3zeta(h):alpha-tubulin 1B(h):Hsp70-1(h):mark1(h) (binding)
14-3-3epsilon(h) + 14-3-3zeta(h) + Hsp70-1(h) + MARK2(h) <==> 14-3-3epsilon(h):14-3-3zeta(h):Hsp70-1(h):MARK2(h) (binding)
14-3-3epsilon(h) + 14-3-3zeta(h) + Hsp70-1(h) + CTAK1(m) <==> 14-3-3epsilon(h):14-3-3zeta(h):Hsp70-1(h):CTAK1(m) (binding)
14-3-3epsilon(h) + 14-3-3zeta(h) + alpha-tubulin 1B(h) + Hsp70-1(h) + MARK4(h) <==> 14-3-3epsilon(h):14-3-3zeta(h):alpha-tubulin 1B(h):Hsp70-1(h):MARK4(h) (binding)
14-3-3zeta(h) + SSH1L(h) <==> 14-3-3zeta(h):SSH1L(h) (binding)
14-3-3zeta(h) + SSH1L(m.s.) <==> 14-3-3zeta(h):SSH1L(m.s.) (binding)
YWHAZ(h) --> 14-3-3zeta(h) (expression).
14-3-3zeta(h) + Rad(m) <==> 14-3-3zeta(h):Rad(m) (binding)
14-3-3zeta(h) + Rem1(m) <==> 14-3-3zeta(h):Rem1(m) (binding)
p27Kip1(h) + 14-3-3zeta(h) <==> p27Kip1(h):14-3-3zeta(h) (binding)
14-3-3zeta(h) + POB1-isoform2(h) <==> 14-3-3zeta(h):POB1-isoform2(h) (binding)
IL-5Rbeta-isoform1(h) + 14-3-3zeta(h) <==> IL-5Rbeta-isoform1(h):14-3-3zeta(h) (binding)
14-3-3zeta(h) + QSK(h) <==> 14-3-3zeta(h):QSK(h) (binding)
SIK(h) + 14-3-3zeta(h) <==> SIK(h):14-3-3zeta(h) (binding)
CTAK1(h) + 14-3-3zeta(h) <==> CTAK1(h):14-3-3zeta(h) (binding)
14-3-3zeta(h) + QSK(h){pT} <==> 14-3-3zeta(h):QSK(h){pT} (binding)
SIK(h) + 14-3-3zeta(h) <==> SIK(h):14-3-3zeta(h) (binding)
QSK(h) + 14-3-3zeta(h) <==> QSK(h):14-3-3zeta(h) (binding)
14-3-3zeta(h) --> TORC2(h){pS70}{pS171}{pS348} (activation; increase of phosphorylation)
YWHAZ(h) --> 14-3-3zeta(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
1	N-acetylmethionine.		Swiss-Prot 53.0
184	Phosphoserine (By similarity).		Swiss-Prot 53.0
232	Phosphothreonine.		Swiss-Prot 53.0
232	Phosphothreonine (CK1 alpha)	16045749;9360956;17081983	Phospho.ELM 6.0
184	Phosphoserine (MAPK8)	15071501	Phospho.ELM 6.0

Chromosome	Location	Source
Methylation Profile [Top]
chr8	Promoter: 102032947 - 102034947	Agilent_014791
chr8	Promoter: 102034245 - 102036245	GSE27584
chr8	Promoter: 102032947 - 102034947	GSE27584

Transcription factors [Top]

Post Translational Modification [Top]

Methylation Profile [Top]