Entrez Gene

Basic Information
Gene ID	7534
Name	YWHAZ

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.683_684GG>AA; p.W228*; 8:100920747-100920748	skin; mucosal	malignant_melanoma	Substitution - Nonsense
c.260A>T; p.E87V; 8:100948630-100948630	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.261G>A; p.E87E; 8:100948629-100948629	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.323A>G; p.N108S; 8:100925011-100925011	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.678+6T>C; p.?; 8:100923949-100923949	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Unknown
c.645G>A; p.T215T; 8:100923988-100923988	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.737A>G; p.246; 8:100920694-100920694	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.263C>T; p.T88M; 8:100948627-100948627	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.264G>T; p.T88T; 8:100948626-100948626	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.650T>G; p.I217R; 8:100923983-100923983	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.518A>C; p.N173T; 8:100924199-100924199	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.312C>A; p.F104L; 8:100925022-100925022	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.629C>T; p.S210L; 8:100924004-100924004	breast	carcinoma	Substitution - Missense
c.689C>T; p.S230L; 8:100920742-100920742	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.255A>T; p.K85N; 8:100948635-100948635	liver	carcinoma	Substitution - Missense
c.255A>T; p.K85N; 8:100948635-100948635	liver	carcinoma	Substitution - Missense
c.678+1G>T; p.?; 8:100923954-100923954	lung; right_upper_lobe	carcinoma; adenocarcinoma	Unknown
c.725G>C; p.G242A; 8:100920706-100920706	urinary_tract; bladder	carcinoma	Substitution - Missense
c.233T>G; p.M78R; 8:100948657-100948657	liver	carcinoma	Substitution - Missense
c.4G>T; p.D2Y; 8:100948886-100948886	ovary	other; neoplasm	Substitution - Missense
c.98G>C; p.G33A; 8:100948792-100948792	breast	carcinoma	Substitution - Missense
c.183C>T; p.V61V; 8:100948707-100948707	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.231G>T; p.Q77H; 8:100948659-100948659	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.240A>G; p.R80R; 8:100948650-100948650	liver	carcinoma	Substitution - coding silent
c.240A>G; p.R80R; 8:100948650-100948650	liver	carcinoma	Substitution - coding silent
c.113A>G; p.N38S; 8:100948777-100948777	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.22C>T; p.Q8*; 8:100948868-100948868	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.238C>G; p.R80G; 8:100948652-100948652	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.697C>G; p.Q233E; 8:100920734-100920734	breast	carcinoma	Substitution - Missense
c.730_731insG; p.E244fs*>3; 8:100920700-100920701	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.730_731insG; p.E244fs*>3; 8:100920700-100920701	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.270A>C; p.L90L; 8:100948620-100948620	liver	carcinoma	Substitution - coding silent
c.270A>C; p.L90L; 8:100948620-100948620	liver	carcinoma	Substitution - coding silent
c.700G>C; p.G234R; 8:100920731-100920731	urinary_tract; bladder	carcinoma	Substitution - Missense
c.372T>G; p.D124E; 8:100924962-100924962	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.293T>C; p.L98P; 8:100948597-100948597	stomach	carcinoma; adenocarcinoma	Substitution - Missense

The somatic mutations from COSMIC database