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dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

7415

Name

VCP

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for VCP
Links to the AnimalTFDB for VCP

Regulation From TransFac database

Herp(m.s.) + HRD1(m.s.) + vcp(h) + Derl1(h) + SELS(h) <==> Herp(m.s.):HRD1(m.s.):vcp(h):Derl1(h):SELS(h) (binding)
3-hydroxy-3-methylglutaryl-coenzyme A reductase(gl){ub} + vcp(h) <==> 3-hydroxy-3-methylglutaryl-coenzyme A reductase(gl){ub}:vcp(h) (binding)
vcp(h) + Gp78(h) <==> vcp(h):Gp78(h) (binding)
vcp(h) + AKT(h) <==> vcp(h):AKT(h) (binding)
NPL4-isoform1(h) + vcp(h) <==> NPL4-isoform1(h):vcp(h) (binding)
MCC1(h) + vcp(h) <==> MCC1(h):vcp(h) (binding)
IKK-i(h) + vcp(h) <==> IKK-i(h):vcp(h) (binding)
PP2Cbeta(h) + vcp(h) <==> PP2Cbeta(h):vcp(h) (binding)
TRAF6(h) + vcp(h) <==> TRAF6(h):vcp(h) (binding)
SGK-1(h) + vcp(h) <==> SGK-1(h):vcp(h) (binding)
wdr8(h) + vcp(h) <==> wdr8(h):vcp(h) (binding)
vcp(h) + SRC-1(h) <==> vcp(h):SRC-1(h) (binding)
HRD1(h) + vcp(h) + Derl1(h) + svip(h) <==> HRD1(h):vcp(h):Derl1(h):svip(h) (binding)
vcp(h) + svip(h) + Derl1(h) + Gp78(h) + HRD1(h) + Ufd1(h) + NPL4(h) <==> vcp(h):svip(h):Derl1(h):Gp78(h):HRD1(h):Ufd1(h):NPL4(h) (binding)
Gp78(h) + Derl1(h) + vcp(h) + SELS(h) <==> Gp78(h):Derl1(h):vcp(h):SELS(h) (binding)
Derl1(h) + vcp(h) + svip(h) <==> Derl1(h):vcp(h):svip(h) (binding)
Derl1(h) + vcp(h) + CD3delta(h) <==> Derl1(h):vcp(h):CD3delta(h) (binding)
Derl1(h) + vcp(h) + Gp78(h) <==> Derl1(h):vcp(h):Gp78(h) (binding)
PEP(h) + vcp(h) <==> PEP(h):vcp(h) (binding)
PP2ACalpha(h) + B55A(h) + alpha-tubulin 1B(h) + PR65-beta(h) + Hsp70-1(h) + vcp(h) <==> PP2ACalpha(h):B55A(h):alpha-tubulin 1B(h):PR65-beta(h):Hsp70-1(h):vcp(h) (binding)
vcp(h) + ATP --> vcp(h){p} + ADP (phosphorylation)
VCP(h) --> vcp(h) (expression).
vcp(h) + Gp78-isoform2(h) + insig-1(h) <==> vcp(h):Gp78-isoform2(h):insig-1(h) (binding)
vcp(h) + 3 ATP --> 3 ADP + vcp(h){pS352}{pS746}{pS748} (phosphorylation)
nup54(r) + vcp(h) <==> nup54(r):vcp(h) (binding)
nupl1-p58(r) + vcp(h) <==> nupl1-p58(r):vcp(h) (binding)
nup62(r) + vcp(h) <==> nup62(r):vcp(h) (binding)
vcp(h) + SRP1alpha(h) <==> vcp(h):SRP1alpha(h) (binding)
VCP(h) --> vcp(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

2N-acetylalanine.Swiss-Prot 53.0
7Phosphoserine (By similarity).Swiss-Prot 53.0
805Phosphotyrosine.Swiss-Prot 53.0
804Phosphotyrosine15592455Phospho.ELM 6.0
351Phosphoserine16027165Phospho.ELM 6.0
745Phosphoserine16027165Phospho.ELM 6.0
747Phosphoserine16027165Phospho.ELM 6.0
783Phosphoserine16140914Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr9

Promoter: 35062064 - 35064064Agilent_014791

chr9

Promoter: 35062064 - 35064064GSE27584


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