Entrez Gene

Basic Information
Gene ID	7415
Name	VCP

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.679C>A; p.P227T; 9:35064183-35064183	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.515C>T; p.P172L; 9:35065312-35065312	thyroid	carcinoma	Substitution - Missense
c.1700G>A; p.R567H; 9:35059797-35059797	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1700G>A; p.R567H; 9:35059797-35059797	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.811+3G>A; p.?; 9:35062975-35062975	stomach	carcinoma; adenocarcinoma	Unknown
c.811+3G>A; p.?; 9:35062975-35062975	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.1830C>T; p.G610G; 9:35059667-35059667	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1337C>T; p.A446V; 9:35061037-35061037	stomach	adenocarcinoma	Substitution - Missense
c.463C>T; p.R155C; 9:35065364-35065364	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.463C>T; p.R155C; 9:35065364-35065364	skin	malignant_melanoma	Substitution - Missense
c.1055G>A; p.S352N; 9:35062029-35062029	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.361G>A; p.D121N; 9:35066759-35066759	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2259G>A; p.R753R; 9:35057432-35057432	breast	carcinoma	Substitution - coding silent
c.2259G>A; p.R753R; 9:35057432-35057432	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.968G>A; p.R323H; 9:35062116-35062116	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.968G>A; p.R323H; 9:35062116-35062116	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.65G>A; p.R22H; 9:35068315-35068315	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1366T>G; p.L456V; 9:35060917-35060917	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2388C>T; p.Y796Y; 9:35057150-35057150	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.552C>A; p.C184*; 9:35065275-35065275	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.396G>A; p.E132E; 9:35066724-35066724	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.867C>G; p.A289A; 9:35062295-35062295	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.867C>G; p.A289A; 9:35062295-35062295	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.812-7C>G; p.?; 9:35062357-35062357	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.2410C>A; p.L804M; 9:35057128-35057128	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2147A>G; p.N716S; 9:35059077-35059077	liver	carcinoma	Substitution - Missense
c.185A>C; p.K62T; 9:35068008-35068008	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.207C>T; p.C69C; 9:35067986-35067986	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.211G>A; p.V71I; 9:35067982-35067982	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1507T>G; p.F503V; 9:35060501-35060501	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1401C>T; p.T467T; 9:35060882-35060882	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.309G>A; p.Q103Q; 9:35066811-35066811	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1317C>T; p.A439A; 9:35061057-35061057	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2179C>A; p.P727T; 9:35057512-35057512	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.303-2A>T; p.?; 9:35066819-35066819	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.442A>T; p.K148*; 9:35066678-35066678	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.236A>T; p.D79V; 9:35067957-35067957	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.596A>G; p.N199S; 9:35064266-35064266	liver	carcinoma	Substitution - Missense
c.441G>C; p.R147R; 9:35066679-35066679	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1557T>A; p.P519P; 9:35060451-35060451	liver	carcinoma	Substitution - coding silent
c.1711C>T; p.P571S; 9:35059786-35059786	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1557T>A; p.P519P; 9:35060451-35060451	liver	carcinoma	Substitution - coding silent
c.2019G>A; p.E673E; 9:35059205-35059205	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.26G>T; p.G9V; 9:35068354-35068354	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1559C>T; p.P520L; 9:35060449-35060449	skin	malignant_melanoma	Substitution - Missense
c.247C>T; p.R83W; 9:35067946-35067946	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1191A>C; p.E397D; 9:35061580-35061580	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1437C>T; p.I479I; 9:35060846-35060846	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2098C>T; p.R700C; 9:35059126-35059126	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1082-1G>C; p.?; 9:35061690-35061690	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.1812C>T; p.I604I; 9:35059685-35059685	liver	carcinoma	Substitution - coding silent
c.1755T>C; p.A585A; 9:35059742-35059742	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1891C>G; p.P631A; 9:35059606-35059606	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.248G>A; p.R83Q; 9:35067945-35067945	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.580G>A; p.E194K; 9:35064282-35064282	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1936C>T; p.P646S; 9:35059561-35059561	skin; mucosal	malignant_melanoma	Substitution - Missense
c.811G>T; p.G271C; 9:35062978-35062978	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1800C>T; p.V600V; 9:35059697-35059697	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.659T>G; p.V220G; 9:35064203-35064203	breast	carcinoma	Substitution - Missense
c.1787C>T; p.A596V; 9:35059710-35059710	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.399A>G; p.V133V; 9:35066721-35066721	skin	malignant_melanoma	Substitution - coding silent
c.787G>T; p.G263*; 9:35063002-35063002	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.85G>C; p.D29H; 9:35068295-35068295	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1023G>A; p.V341V; 9:35062061-35062061	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.928G>A; p.A310T; 9:35062234-35062234	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.920A>T; p.D307V; 9:35062242-35062242	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1076G>A; p.R359Q; 9:35062008-35062008	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1553G>T; p.G518V; 9:35060455-35060455	pancreas	carcinoma	Substitution - Missense
c.1913G>A; p.R638H; 9:35059584-35059584	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2297G>A; p.R766Q; 9:35057394-35057394	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1847delA; p.N616fs*63; 9:35059650-35059650	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1847delA; p.N616fs*63; 9:35059650-35059650	pancreas	carcinoma; acinar_carcinoma	Deletion - Frameshift
c.1058T>A; p.I353N; 9:35062026-35062026	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1275G>T; p.K425N; 9:35061099-35061099	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1847delA; p.N616fs*63; 9:35059650-35059650	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1847delA; p.N616fs*63; 9:35059650-35059650	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1847delA; p.N616fs*63; 9:35059650-35059650	oesophagus; lower_third	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1847delA; p.N616fs*63; 9:35059650-35059650	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1285C>T; p.L429F; 9:35061089-35061089	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1847delA; p.N616fs*63; 9:35059650-35059650	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1847delA; p.N616fs*63; 9:35059650-35059650	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1847_1848insA; p.N616fs*12; 9:35059649-35059650	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.547C>T; p.H183Y; 9:35065280-35065280	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1847_1848insA; p.N616fs*12; 9:35059649-35059650	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1847_1848insA; p.N616fs*12; 9:35059649-35059650	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.225T>G; p.D75E; 9:35067968-35067968	liver	carcinoma	Substitution - Missense
c.1130G>A; p.R377H; 9:35061641-35061641	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2000C>T; p.A667V; 9:35059497-35059497	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.421G>A; p.E141K; 9:35066699-35066699	skin	malignant_melanoma	Substitution - Missense
c.1202A>G; p.N401S; 9:35061172-35061172	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1202A>G; p.N401S; 9:35061172-35061172	breast	carcinoma	Substitution - Missense
c.348G>A; p.V116V; 9:35066772-35066772	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1904G>C; p.R635T; 9:35059593-35059593	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1418A>T; p.Q473L; 9:35060865-35060865	liver	carcinoma	Substitution - Missense
c.1418A>T; p.Q473L; 9:35060865-35060865	liver	carcinoma	Substitution - Missense
c.1743G>A; p.S581S; 9:35059754-35059754	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.440G>C; p.R147P; 9:35066680-35066680	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.277C>T; p.R93C; 9:35067916-35067916	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1198G>T; p.A400S; 9:35061176-35061176	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1198G>T; p.A400S; 9:35061176-35061176	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1198G>T; p.A400S; 9:35061176-35061176	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1314T>C; p.D438D; 9:35061060-35061060	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.1675G>A; p.V559I; 9:35060333-35060333	breast	carcinoma	Substitution - Missense
c.1725C>A; p.F575L; 9:35059772-35059772	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1400C>T; p.T467I; 9:35060883-35060883	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1937C>A; p.P646Q; 9:35059560-35059560	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.767G>A; p.R256Q; 9:35063022-35063022	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2320C>T; p.P774S; 9:35057218-35057218	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2320C>T; p.P774S; 9:35057218-35057218	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2110G>A; p.E704K; 9:35059114-35059114	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2222G>A; p.R741H; 9:35057469-35057469	liver	carcinoma	Substitution - Missense
c.766C>T; p.R256*; 9:35063023-35063023	pituitary; craniopharyngeal_duct	craniopharyngioma; adamantinomatous	Substitution - Nonsense
c.1271G>A; p.R424H; 9:35061103-35061103	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1917T>C; p.L639L; 9:35059580-35059580	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.574G>C; p.E192Q; 9:35065253-35065253	breast	carcinoma	Substitution - Missense
c.2214A>G; p.E738E; 9:35057477-35057477	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1653G>A; p.W551*; 9:35060355-35060355	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1318G>T; p.E440*; 9:35061056-35061056	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2144C>T; p.T715I; 9:35059080-35059080	lung; left_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2371A>C; p.T791P; 9:35057167-35057167	pituitary; craniopharyngeal_duct	craniopharyngioma; adamantinomatous	Substitution - Missense
c.801_803delCTT; p.F267delF; 9:35062986-35062988	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - In frame
c.2347C>A; p.P783T; 9:35057191-35057191	liver	carcinoma	Substitution - Missense
c.1921C>T; p.Q641*; 9:35059576-35059576	breast	carcinoma	Substitution - Nonsense
c.969C>T; p.R323R; 9:35062115-35062115	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.915G>A; p.E305E; 9:35062247-35062247	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1105A>G; p.I369V; 9:35061666-35061666	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1105A>G; p.I369V; 9:35061666-35061666	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.951T>C; p.H317H; 9:35062133-35062133	liver	carcinoma	Substitution - coding silent
c.951T>C; p.H317H; 9:35062133-35062133	liver	carcinoma	Substitution - coding silent
c.88G>A; p.E30K; 9:35068292-35068292	skin	malignant_melanoma	Substitution - Missense
c.393C>T; p.F131F; 9:35066727-35066727	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent

The somatic mutations from COSMIC database