Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

5743

Name

PTGS2

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for PTGS2
Links to the AnimalTFDB for PTGS2

Regulation From TransFac database

2 COX2(h) <==> (COX2(h))2 (binding; oligomerization)
COX2(h) --> PGI2 (increase of secretion)
PTGS2(h) --> COX2(h) (expression).
EGF(h) --> COX2(h) (increase of abundance)
C/EBPdelta(h) --> COX2(h) (increase of abundance)
LPA --> COX2(h) (increase of abundance)
LPA2(h) --> COX2(h) (increase of abundance)
Substance P(m.s.) --> COX2(h) (increase of abundance)
histamine --> COX2(h) (increase of abundance)
LPS --> COX2(h) (increase of abundance)
IL-17A(h) --> COX2(h) (increase of abundance)
ET-1(m.s.) --> COX2(h) (increase of abundance)
ET3(m.s.) --> COX2(h) (increase of abundance)
IFNalpha(m.s.) --> COX2(h) (increase of abundance)
PTGS2(h) --> COX2(h) (expression).
PTGS2(h) --> COX2(h) (expression).
hsa-miR-101 --/ COX2(h) (translational repression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

53N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
130N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
396N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
580N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr1

 Promoter: 184915679 - 184917679Agilent_014791

chr1

 Promoter: 184915679 - 184917679GoldenGate_Methylation_Cancer_Panel_I

chr1

 Promoter: 184915679 - 184917679GSE27584

chr1

 Promoter: 184915679 - 184917679Agilent_014791_44K

chr1

 Promoter: 184915679 - 184917679PMID:12695555

chr1

 Promoter: 184915679 - 184917679PMID:14550281

chr1

 Promoter: 184915679 - 184917679PMID:11389100

chr1

 Promoter: 184915679 - 184917679PMID:12746473

chr1

 Promoter: 184915679 - 184917679PMID:12684668

chr1

 Promoter: 184915679 - 184917679PMID:12763209

chr1

 Promoter: 184915679 - 184917679PMID:14507661

chr1

 Promoter: 184915679 - 184917679PMID:16949912

chr1

 Promoter: 184915679 - 184917679PMID:11774276

chr1

 Promoter: 184915679 - 184917679PMID:16956712

chr1

 Promoter: 184915679 - 184917679PMID:15026333

chr1

 Promoter: 184915679 - 184917679PMID:16489065

chr1

 Promoter: 184915679 - 184917679PMID:15930345

chr1

 Promoter: 184915679 - 184917679PMID:15899813

chr1

 Promoter: 184915679 - 184917679PMID:17139617

chr1

 Promoter: 184915679 - 184917679PMID:15526363

chr1

 Promoter: 184915679 - 184917679PMID:15122305

chr1

 Promoter: 184915679 - 184917679PMID:16551850

chr1

 Promoter: 184915679 - 184917679PMID:10945606

chr1

 Promoter: 184915679 - 184917679PMID:15156159

chr1

 Promoter: 184915679 - 184917679PMID:12011226

chr1

 Promoter: 184915679 - 184917679PMID:14507645

chr1

 Promoter: 184915679 - 184917679PMID:16565510

chr1

 Promoter: 184915679 - 184917679PMID:12213730

chr1

 Promoter: 184915679 - 184917679PMID:11895880

chr1

 Promoter: 184915679 - 184917679PMID:15639718

chr1

 Promoter: 184915679 - 184917679PMID:16435073

chr1

 Promoter: 184915679 - 184917679PMID:16507389

chr1

 Promoter: 184915679 - 184917679PMID:15172987

chr1

 Promoter: 184915679 - 184917679PMID:12730870

chr1

 Promoter: 184915679 - 184917679PMID:15589597

chr1

 Promoter: 184915679 - 184917679PMID:16242928

chr1

 Promoter: 184915679 - 184917679PMID:15723947

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