Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

4323

Name

MMP14

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for MMP14
Links to the AnimalTFDB for MMP14

Regulation From TransFac database

MMP14(h) --> MT1-MMP(h) (expression).
fibronectin(h) --> MT1-MMP(h) (increase of abundance)
TNF-alpha(m.s.) --> MT1-MMP(h) (increase of abundance)
MT1-MMP(h) + caveolin-1(mo) <==> MT1-MMP(h):caveolin-1(mo) (binding)
MT1-MMP(h) + caveolin-1(mo){pY} <==> MT1-MMP(h):caveolin-1(mo){pY} (binding)
caveolin-1(m.s.) + MT1-MMP(h) <==> caveolin-1(m.s.):MT1-MMP(h) (binding)
MT1-MMP(h) --> Src(m.s.):caveolin-1(mo) (increase of binding)
MMP14(h) --> MT1-MMP(h) (expression).
TGC(h) --MT1-MMP(h)--> TGC-p70(h) + protein remnants (cleavage)
TGC(h) --MT1-MMP(h)--> TGC-p53(h) + protein remnants (cleavage)
TGC(h) --MT1-MMP(h)--> TGC-p32(h) + TGC-p41(h) + protein remnants (cleavage)

Post Translational Modification   [Top]

There is no record for MMP14

Methylation Profile   [Top]

Chromosome

Location

Source

chr14

Promoter: 22374133 - 22376133GoldenGate_Methylation_Cancer_Panel_I

chr14

Promoter: 22374133 - 22376133GSE27584

chr14

Promoter: 22374133 - 22376133Agilent_014791_44K


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