| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4216 |
Name | MAP3K4 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for MAP3K4 |
| Links to the AnimalTFDB for MAP3K4 |
Regulation From TransFac database | TRAF4(h) + MEKK4(h) <==> TRAF4(h):MEKK4(h) (binding) | annexin-A2(h) + MEKK4(h) <==> annexin-A2(h):MEKK4(h) (binding) | MEKK4(h) + Pyk2(h) <==> MEKK4(h):Pyk2(h) (binding) | MEKK4(h) + ATP --> MEKK4(h){pY} + ADP (phosphorylation) | MEKK4(h) + ATP --Pyk2(h)--> MEKK4(h){pY} + ADP (phosphorylation) | MEKK4(h) + ATP --> MEKK4(h){p} + ADP (phosphorylation; automodification) | MEKK4(h) + SHP-2(h) <==> MEKK4(h):SHP-2(h) (binding) | MAP3K4(h) --> MEKK4(h) (expression). | MEKK4(h){pY} --SHP-2(h)--> p + MEKK4(h) (dephosphorylation) | MKK6(h) + ATP --MEKK4(h)--> MKK6(h){p} + ADP (phosphorylation) | MKK6(m.s.) + ATP --MEKK4(h)--> MKK6(m.s.){p} + ADP (phosphorylation) | MAP3K4(h) --> MEKK4-A(h) (expression). | MAP3K4(h) --> MEKK4-xbb2(h) (expression). | MAP3K4(h) --> MEKK4-B(h) (expression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 499 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 1504 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr6 |
Promoter: 161331312 - 161333312 | Agilent_014791 |
chr6 |
Promoter: 161331312 - 161333312 | GSE27584 |
chr6 |
Promoter: 161331312 - 161333312 | GSE27584 |
chr6 |
Promoter: 161331312 - 161333312 | Agilent_014791_44K |