Entrez Gene

Basic Information
Gene ID	4216
Name	MAP3K4

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.2973G>T; p.K991N; 6:161089471-161089471	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.281G>A; p.R94H; 6:161034387-161034387	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2900A>G; p.E967G; 6:161089398-161089398	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2900A>G; p.E967G; 6:161089398-161089398	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2473G>T; p.D825Y; 6:161086584-161086584	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2939A>G; p.Q980R; 6:161089437-161089437	skin	malignant_melanoma	Substitution - Missense
c.2900A>G; p.E967G; 6:161089398-161089398	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2004C>T; p.Y668Y; 6:161073519-161073519	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2458A>G; p.K820E; 6:161086464-161086464	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2004C>T; p.Y668Y; 6:161073519-161073519	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.895C>T; p.L299F; 6:161049167-161049167	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.895C>T; p.L299F; 6:161049167-161049167	skin	malignant_melanoma	Substitution - Missense
c.3149T>G; p.V1050G; 6:161092023-161092023	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3524+3A>G; p.?; 6:161097179-161097179	liver	carcinoma	Unknown
c.3524+3A>G; p.?; 6:161097179-161097179	liver	carcinoma	Unknown
c.2725C>T; p.R909*; 6:161087856-161087856	breast	carcinoma	Substitution - Nonsense
c.524_525insA; p.S178fs*9; 6:161048796-161048797	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.524_525insA; p.S178fs*9; 6:161048796-161048797	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.524_525insA; p.S178fs*9; 6:161048796-161048797	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.3334G>A; p.E1112K; 6:161093042-161093042	skin	malignant_melanoma	Substitution - Missense
c.2395C>T; p.R799*; 6:161086401-161086401	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.4077delC; p.C1360fs*9; 6:161107927-161107927	endometrium	carcinoma; serous_carcinoma	Deletion - Frameshift
c.4168G>A; p.E1390K; 6:161108791-161108791	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.4168G>A; p.E1390K; 6:161108791-161108791	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3178C>T; p.Q1060*; 6:161092052-161092052	skin	malignant_melanoma	Substitution - Nonsense
c.224C>T; p.T75I; 6:161034330-161034330	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.2023G>T; p.E675*; 6:161073538-161073538	large_intestine; colon	adenoma	Substitution - Nonsense
c.2082A>G; p.L694L; 6:161073597-161073597	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.81_82insCCG; p.P36_E37insP; 6:160992012-160992013	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Insertion - In frame
c.268C>T; p.R90*; 6:161034374-161034374	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2504C>A; p.S835*; 6:161086615-161086615	breast	carcinoma	Substitution - Nonsense
c.4733T>G; p.L1578R; 6:161115229-161115229	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2683G>A; p.V895I; 6:161087814-161087814	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.697C>A; p.L233I; 6:161048969-161048969	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.3547G>A; p.A1183T; 6:161098300-161098300	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2078A>T; p.D693V; 6:161073593-161073593	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.448C>T; p.L150F; 6:161048720-161048720	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4082T>G; p.I1361S; 6:161107932-161107932	central_nervous_system; brain	glioma	Substitution - Missense
c.4182C>T; p.F1394F; 6:161108805-161108805	skin	malignant_melanoma	Substitution - coding silent
c.4182C>T; p.F1394F; 6:161108805-161108805	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1708-2A>G; p.?; 6:161070606-161070606	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1015A>T; p.T339S; 6:161049287-161049287	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3301G>C; p.A1101P; 6:161093009-161093009	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1514G>T; p.G505V; 6:161049786-161049786	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1232G>A; p.G411D; 6:161049504-161049504	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.166T>C; p.L56L; 6:161034272-161034272	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.95_96insGCC; p.P36_E37insP; 6:160992026-160992027	lung	carcinoma; adenocarcinoma	Insertion - In frame
c.249C>T; p.T83T; 6:161034355-161034355	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3267C>T; p.P1089P; 6:161092141-161092141	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1153G>T; p.D385Y; 6:161049425-161049425	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.755C>T; p.T252M; 6:161049027-161049027	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.90G>A; p.P30P; 6:160992021-160992021	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1120C>T; p.L374F; 6:161049392-161049392	skin	malignant_melanoma	Substitution - Missense
c.1547G>T; p.G516V; 6:161049819-161049819	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3723A>G; p.E1241E; 6:161101940-161101940	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.3399A>G; p.P1133P; 6:161093823-161093823	liver	carcinoma	Substitution - coding silent
c.710C>T; p.S237L; 6:161048982-161048982	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3593C>T; p.A1198V; 6:161098346-161098346	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.4578C>T; p.A1526A; 6:161112726-161112726	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3448C>T; p.R1150C; 6:161097100-161097100	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4578C>T; p.A1526A; 6:161112726-161112726	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.4578C>T; p.A1526A; 6:161112726-161112726	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3448C>T; p.R1150C; 6:161097100-161097100	skin	malignant_melanoma	Substitution - Missense
c.2065G>A; p.A689T; 6:161073580-161073580	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1723G>T; p.D575Y; 6:161070623-161070623	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1315G>T; p.E439*; 6:161049587-161049587	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.298C>T; p.Q100*; 6:161034404-161034404	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.2388G>A; p.E796E; 6:161086394-161086394	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1450A>G; p.I484V; 6:161049722-161049722	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1450A>G; p.I484V; 6:161049722-161049722	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4822G>A; p.E1608K; 6:161116865-161116865	breast	carcinoma	Substitution - Missense
c.1450A>G; p.I484V; 6:161049722-161049722	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1882C>T; p.H628Y; 6:161070782-161070782	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3967G>A; p.D1323N; 6:161106624-161106624	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1150A>G; p.K384E; 6:161049422-161049422	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4533T>C; p.P1511P; 6:161112681-161112681	breast	carcinoma	Substitution - coding silent
c.670A>C; p.K224Q; 6:161048942-161048942	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2688C>T; p.L896L; 6:161087819-161087819	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1693G>T; p.D565Y; 6:161049965-161049965	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1951-2A>G; p.?; 6:161073464-161073464	oesophagus	carcinoma; adenocarcinoma	Unknown
c.81A>G; p.P27P; 6:160992012-160992012	pancreas	carcinoma	Substitution - coding silent
c.4034G>C; p.R1345T; 6:161106691-161106691	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1374G>T; p.T458T; 6:161049646-161049646	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4089C>G; p.V1363V; 6:161107939-161107939	ovary	other; neoplasm	Substitution - coding silent
c.3518G>A; p.G1173E; 6:161097170-161097170	skin	malignant_melanoma	Substitution - Missense
c.3566_3568delCTG; p.A1199delA; 6:161098319-161098321	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - In frame
c.3566_3568delCTG; p.A1199delA; 6:161098319-161098321	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - In frame
c.3566_3568delCTG; p.A1199delA; 6:161098319-161098321	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - In frame
c.3566_3568delCTG; p.A1199delA; 6:161098319-161098321	breast	carcinoma	Deletion - In frame
c.3566_3568delCTG; p.A1199delA; 6:161098319-161098321	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - In frame
c.3566_3568delCTG; p.A1199delA; 6:161098319-161098321	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - In frame
c.3566_3568delCTG; p.A1199delA; 6:161098319-161098321	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - In frame
c.3566_3568delCTG; p.A1199delA; 6:161098319-161098321	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - In frame
c.3566_3568delCTG; p.A1199delA; 6:161098319-161098321	breast	carcinoma	Deletion - In frame
c.3566_3568delCTG; p.A1199delA; 6:161098319-161098321	breast	carcinoma	Deletion - In frame
c.730A>G; p.R244G; 6:161049002-161049002	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3566_3568delCTG; p.A1199delA; 6:161098319-161098321	lung	carcinoma; adenocarcinoma	Deletion - In frame
c.3566_3568delCTG; p.A1199delA; 6:161098319-161098321	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - In frame
c.3566_3568delCTG; p.A1199delA; 6:161098319-161098321	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - In frame
c.3904C>T; p.R1302*; 6:161106561-161106561	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3566_3568delCTG; p.A1199delA; 6:161098319-161098321	breast	carcinoma	Deletion - In frame
c.3566_3568delCTG; p.A1199delA; 6:161098319-161098321	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - In frame
c.3566_3568delCTG; p.A1199delA; 6:161098319-161098321	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - In frame
c.3999C>G; p.H1333Q; 6:161106656-161106656	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1092A>G; p.I364M; 6:161049364-161049364	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2156C>T; p.S719L; 6:161080939-161080939	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3203G>T; p.S1068I; 6:161092077-161092077	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.868G>C; p.A290P; 6:161049140-161049140	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3467G>A; p.R1156Q; 6:161097119-161097119	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2611G>A; p.E871K; 6:161087742-161087742	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1447G>T; p.D483Y; 6:161049719-161049719	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.4681G>T; p.G1561*; 6:161115177-161115177	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2002T>C; p.Y668H; 6:161073517-161073517	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2002T>C; p.Y668H; 6:161073517-161073517	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3234G>A; p.L1078L; 6:161092108-161092108	skin	malignant_melanoma	Substitution - coding silent
c.1447G>T; p.D483Y; 6:161049719-161049719	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1211A>C; p.N404T; 6:161049483-161049483	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.439C>G; p.R147G; 6:161048711-161048711	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2227G>A; p.G743R; 6:161081010-161081010	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1420delA; p.I474fs*5; 6:161049692-161049692	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Deletion - Frameshift
c.1571C>T; p.S524F; 6:161049843-161049843	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2943G>A; p.P981P; 6:161089441-161089441	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1728C>T; p.P576P; 6:161070628-161070628	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.4570C>T; p.R1524C; 6:161112718-161112718	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2783T>C; p.V928A; 6:161087914-161087914	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.3345C>A; p.F1115L; 6:161093053-161093053	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3832C>T; p.R1278W; 6:161102755-161102755	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.3852T>C; p.S1284S; 6:161102775-161102775	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.525delA; p.K177fs*30; 6:161048797-161048797	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.525delA; p.K177fs*30; 6:161048797-161048797	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2327A>G; p.E776G; 6:161084572-161084572	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1018C>G; p.H340D; 6:161049290-161049290	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3626G>T; p.G1209V; 6:161098379-161098379	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3715G>T; p.A1239S; 6:161101932-161101932	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2883T>G; p.A961A; 6:161089381-161089381	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1814A>G; p.K605R; 6:161070714-161070714	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4173G>T; p.L1391F; 6:161108796-161108796	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3913G>A; p.E1305K; 6:161106570-161106570	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3833G>A; p.R1278Q; 6:161102756-161102756	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.974A>G; p.Q325R; 6:161049246-161049246	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3833G>A; p.R1278Q; 6:161102756-161102756	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4547G>A; p.R1516H; 6:161112695-161112695	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3212G>A; p.R1071Q; 6:161092086-161092086	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.515G>A; p.G172E; 6:161048787-161048787	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.234G>T; p.E78D; 6:161034340-161034340	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1729A>G; p.M577V; 6:161070629-161070629	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.471_472insA; p.N160fs*27; 6:161048743-161048744	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.3319A>T; p.I1107F; 6:161093027-161093027	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4567G>T; p.G1523W; 6:161112715-161112715	liver	carcinoma	Substitution - Missense
c.1800G>A; p.S600S; 6:161070700-161070700	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2441A>G; p.K814R; 6:161086447-161086447	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2441A>G; p.K814R; 6:161086447-161086447	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3661G>C; p.A1221P; 6:161098414-161098414	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4617G>A; p.V1539V; 6:161112765-161112765	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4124G>A; p.R1375Q; 6:161108747-161108747	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1696C>T; p.R566C; 6:161049968-161049968	skin	malignant_melanoma	Substitution - Missense
c.1356_1357delGG; p.E453fs*4; 6:161049628-161049629	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4405A>G; p.I1469V; 6:161111844-161111844	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2901G>T; p.E967D; 6:161089399-161089399	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.387delA; p.T131fs*37; 6:161048659-161048659	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4405A>G; p.I1469V; 6:161111844-161111844	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.4048G>T; p.G1350*; 6:161106705-161106705	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3199A>G; p.I1067V; 6:161092073-161092073	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.3446C>T; p.P1149L; 6:161097098-161097098	skin	malignant_melanoma	Substitution - Missense
c.4090G>A; p.D1364N; 6:161107940-161107940	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2291G>C; p.S764T; 6:161084536-161084536	skin	malignant_melanoma	Substitution - Missense
c.4385G>A; p.R1462H; 6:161109903-161109903	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4385G>A; p.R1462H; 6:161109903-161109903	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2203G>A; p.E735K; 6:161080986-161080986	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2389A>T; p.I797F; 6:161086395-161086395	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.4400C>T; p.A1467V; 6:161111839-161111839	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.4772C>A; p.T1591N; 6:161115268-161115268	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1725T>C; p.D575D; 6:161070625-161070625	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2241C>T; p.A747A; 6:161081024-161081024	thyroid	other; neoplasm	Substitution - coding silent
c.1725T>C; p.D575D; 6:161070625-161070625	large_intestine; rectum	NS	Substitution - coding silent
c.280C>A; p.R94S; 6:161034386-161034386	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2388_2389GA>AT; p.I797F; 6:161086394-161086395	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1690A>T; p.N564Y; 6:161049962-161049962	pancreas	carcinoma	Substitution - Missense
c.1623G>T; p.K541N; 6:161049895-161049895	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.4636C>T; p.H1546Y; 6:161115132-161115132	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.906A>G; p.K302K; 6:161049178-161049178	skin	malignant_melanoma	Substitution - coding silent
c.863G>A; p.R288H; 6:161049135-161049135	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4443T>A; p.D1481E; 6:161111882-161111882	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4443T>A; p.D1481E; 6:161111882-161111882	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2945T>C; p.V982A; 6:161089443-161089443	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3043G>A; p.E1015K; 6:161091448-161091448	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.3010G>A; p.A1004T; 6:161091415-161091415	bone; femur	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.3010G>A; p.A1004T; 6:161091415-161091415	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.710C>A; p.S237*; 6:161048982-161048982	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Nonsense
c.3276G>A; p.A1092A; 6:161092984-161092984	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1959A>T; p.R653S; 6:161073474-161073474	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1637T>G; p.L546R; 6:161049909-161049909	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2005T>C; p.Y669H; 6:161073520-161073520	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1724A>G; p.D575G; 6:161070624-161070624	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4237G>C; p.E1413Q; 6:161109755-161109755	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.4237G>C; p.E1413Q; 6:161109755-161109755	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.3548C>T; p.A1183V; 6:161098301-161098301	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4575G>A; p.A1525A; 6:161112723-161112723	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.840G>T; p.Q280H; 6:161049112-161049112	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.4093A>G; p.T1365A; 6:161107943-161107943	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4096G>A; p.G1366R; 6:161107946-161107946	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.784G>A; p.E262K; 6:161049056-161049056	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.784G>A; p.E262K; 6:161049056-161049056	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.784G>A; p.E262K; 6:161049056-161049056	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.4096G>A; p.G1366R; 6:161107946-161107946	skin	malignant_melanoma	Substitution - Missense
c.4096G>A; p.G1366R; 6:161107946-161107946	skin	malignant_melanoma	Substitution - Missense
c.784G>A; p.E262K; 6:161049056-161049056	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4384C>T; p.R1462C; 6:161109902-161109902	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.548A>C; p.D183A; 6:161048820-161048820	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4266C>T; p.C1422C; 6:161109784-161109784	pancreas	carcinoma	Substitution - coding silent
c.2472+1G>A; p.?; 6:161086479-161086479	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.2566C>T; p.P856S; 6:161087697-161087697	skin	malignant_melanoma	Substitution - Missense
c.711A>T; p.S237S; 6:161048983-161048983	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1084G>T; p.E362*; 6:161049356-161049356	breast	carcinoma	Substitution - Nonsense
c.1656T>C; p.G552G; 6:161049928-161049928	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.472delA; p.N160fs*8; 6:161048744-161048744	skin	malignant_melanoma	Deletion - Frameshift
c.472delA; p.N160fs*8; 6:161048744-161048744	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.664C>T; p.R222C; 6:161048936-161048936	skin	malignant_melanoma	Substitution - Missense
c.3222G>T; p.M1074I; 6:161092096-161092096	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3809C>T; p.S1270F; 6:161102732-161102732	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.472delA; p.N160fs*8; 6:161048744-161048744	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.417C>A; p.S139R; 6:161048689-161048689	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1415C>T; p.P472L; 6:161049687-161049687	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.472delA; p.N160fs*8; 6:161048744-161048744	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.472delA; p.N160fs*8; 6:161048744-161048744	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.472delA; p.N160fs*8; 6:161048744-161048744	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.664C>T; p.R222C; 6:161048936-161048936	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.200A>T; p.D67V; 6:161034306-161034306	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.159G>T; p.E53D; 6:161034265-161034265	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1591G>C; p.D531H; 6:161049863-161049863	central_nervous_system; brain	glioma	Substitution - Missense
c.4008G>C; p.L1336F; 6:161106665-161106665	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3684C>T; p.S1228S; 6:161101901-161101901	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4223T>A; p.V1408E; 6:161108846-161108846	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4579G>A; p.D1527N; 6:161112727-161112727	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4576G>A; p.A1526T; 6:161112724-161112724	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4437G>C; p.L1479L; 6:161111876-161111876	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1827A>G; p.L609L; 6:161070727-161070727	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.714C>G; p.V238V; 6:161048986-161048986	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4098G>T; p.G1366G; 6:161107948-161107948	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4097G>A; p.G1366E; 6:161107947-161107947	soft_tissue; fat	liposarcoma; myxoid-round_cell	Substitution - Missense
c.1837G>T; p.E613*; 6:161070737-161070737	ovary	other; neoplasm	Substitution - Nonsense
c.3311C>G; p.P1104R; 6:161093019-161093019	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.4726G>A; p.D1576N; 6:161115222-161115222	skin	malignant_melanoma	Substitution - Missense
c.2218A>G; p.I740V; 6:161081001-161081001	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1373C>T; p.T458M; 6:161049645-161049645	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4267G>A; p.D1423N; 6:161109785-161109785	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1447G>A; p.D483N; 6:161049719-161049719	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1726C>T; p.P576S; 6:161070626-161070626	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1447G>A; p.D483N; 6:161049719-161049719	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3752C>A; p.S1251*; 6:161101969-161101969	breast	carcinoma	Substitution - Nonsense
c.1980G>A; p.K660K; 6:161073495-161073495	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1409delG; p.V471fs*8; 6:161049681-161049681	breast	carcinoma	Deletion - Frameshift
c.2719G>T; p.G907C; 6:161087850-161087850	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4239A>G; p.E1413E; 6:161109757-161109757	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.319C>T; p.P107S; 6:161034425-161034425	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.319C>T; p.P107S; 6:161034425-161034425	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.365A>T; p.Q122L; 6:161048637-161048637	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4239A>G; p.E1413E; 6:161109757-161109757	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4514C>T; p.T1505I; 6:161111953-161111953	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2858C>T; p.A953V; 6:161089356-161089356	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3939G>C; p.R1313S; 6:161106596-161106596	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4761G>C; p.K1587N; 6:161115257-161115257	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.4273G>A; p.G1425R; 6:161109791-161109791	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4299G>T; p.L1433L; 6:161109817-161109817	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2196C>T; p.F732F; 6:161080979-161080979	breast	carcinoma	Substitution - coding silent
c.1179C>T; p.L393L; 6:161049451-161049451	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3758C>A; p.P1253H; 6:161101975-161101975	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.689G>A; p.R230Q; 6:161048961-161048961	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3022G>A; p.V1008M; 6:161091427-161091427	NS	malignant_melanoma	Substitution - Missense
c.3596C>T; p.A1199V; 6:161098349-161098349	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3596C>T; p.A1199V; 6:161098349-161098349	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3596C>T; p.A1199V; 6:161098349-161098349	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3596C>T; p.A1199V; 6:161098349-161098349	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3596C>T; p.A1199V; 6:161098349-161098349	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3596C>T; p.A1199V; 6:161098349-161098349	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2683G>T; p.V895L; 6:161087814-161087814	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.4236+7C>T; p.?; 6:161108866-161108866	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.472A>G; p.K158E; 6:161048744-161048744	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.4221T>A; p.G1407G; 6:161108844-161108844	breast	carcinoma	Substitution - coding silent
c.1251G>T; p.K417N; 6:161049523-161049523	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1458G>A; p.S486S; 6:161049730-161049730	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4111A>G; p.M1371V; 6:161107961-161107961	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3710C>T; p.S1237F; 6:161101927-161101927	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4076C>G; p.T1359S; 6:161107926-161107926	breast	carcinoma	Substitution - Missense
c.4214A>G; p.Y1405C; 6:161108837-161108837	oesophagus	carcinoma	Substitution - Missense
c.4424G>T; p.G1475V; 6:161111863-161111863	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4622G>C; p.G1541A; 6:161112770-161112770	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1340C>T; p.T447I; 6:161049612-161049612	breast	carcinoma	Substitution - Missense
c.1521A>G; p.G507G; 6:161049793-161049793	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1471T>G; p.S491A; 6:161049743-161049743	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2504C>T; p.S835L; 6:161086615-161086615	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.948T>C; p.G316G; 6:161049220-161049220	pancreas	carcinoma	Substitution - coding silent
c.3275C>T; p.A1092V; 6:161092983-161092983	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2892G>A; p.Q964Q; 6:161089390-161089390	breast	carcinoma	Substitution - coding silent
c.260G>A; p.S87N; 6:161034366-161034366	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4004G>A; p.G1335D; 6:161106661-161106661	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2297T>C; p.L766S; 6:161084542-161084542	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.923T>A; p.F308Y; 6:161049195-161049195	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.824G>A; p.R275Q; 6:161049096-161049096	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.824G>A; p.R275Q; 6:161049096-161049096	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.541G>T; p.D181Y; 6:161048813-161048813	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.4720_4721GG>AA; p.G1574K; 6:161115216-161115217	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.567C>T; p.L189L; 6:161048839-161048839	breast	carcinoma	Substitution - coding silent
c.2682C>T; p.D894D; 6:161087813-161087813	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3245A>G; p.E1082G; 6:161092119-161092119	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2726G>A; p.R909Q; 6:161087857-161087857	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2901G>A; p.E967E; 6:161089399-161089399	skin	malignant_melanoma	Substitution - coding silent
c.2901G>A; p.E967E; 6:161089399-161089399	skin	malignant_melanoma	Substitution - coding silent
c.3972G>A; p.T1324T; 6:161106629-161106629	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3313G>A; p.A1105T; 6:161093021-161093021	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4324C>T; p.L1442L; 6:161109842-161109842	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1446C>T; p.F482F; 6:161049718-161049718	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1288C>A; p.P430T; 6:161049560-161049560	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4237G>T; p.E1413*; 6:161109755-161109755	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1848C>G; p.F616L; 6:161070748-161070748	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1149A>C; p.A383A; 6:161049421-161049421	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3423C>T; p.Y1141Y; 6:161093847-161093847	skin	malignant_melanoma	Substitution - coding silent
c.3423C>T; p.Y1141Y; 6:161093847-161093847	skin	malignant_melanoma	Substitution - coding silent
c.3695A>G; p.N1232S; 6:161101912-161101912	liver	carcinoma	Substitution - Missense
c.83C>A; p.P28Q; 6:160992014-160992014	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.898A>G; p.T300A; 6:161049170-161049170	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3695A>G; p.N1232S; 6:161101912-161101912	liver	carcinoma	Substitution - Missense
c.847T>G; p.F283V; 6:161049119-161049119	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2504C>G; p.S835*; 6:161086615-161086615	breast	carcinoma	Substitution - Nonsense
c.96A>G; p.P32P; 6:160992027-160992027	liver	carcinoma	Substitution - coding silent
c.96A>G; p.P32P; 6:160992027-160992027	liver	carcinoma	Substitution - coding silent
c.1261G>C; p.D421H; 6:161049533-161049533	urinary_tract; bladder	carcinoma	Substitution - Missense
c.925G>A; p.A309T; 6:161049197-161049197	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3568G>C; p.A1190P; 6:161098321-161098321	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense

The somatic mutations from COSMIC database