| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3690 |
Name | ITGB3 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for ITGB3 |
| Links to the AnimalTFDB for ITGB3 |
Regulation From TransFac database | VEGFR-2(h) + beta3-integrin(h) <==> VEGFR-2(h):beta3-integrin(h) (binding) | LAP1(h) + CD51(h) + beta3-integrin(h) <==> LAP1(h):CD51(h):beta3-integrin(h) (binding) | beta3-integrin(h) + beta3-endonexin(h) <==> beta3-integrin(h):beta3-endonexin(h) (binding) | beta3-integrin(h) + talin(h) <==> beta3-integrin(h):talin(h) (binding) | beta3-integrin(h) + Syk(h) <==> beta3-integrin(h):Syk(h) (binding) | beta3-integrin(h) + ABP-280(h) <==> beta3-integrin(h):ABP-280(h) (binding) | beta3-integrin(h) + ZAP-70(h) <==> beta3-integrin(h):ZAP-70(h) (binding) | Cas(h) + EGFR(h) + CD51(h) + beta3-integrin(h) + Src(h) <==> Cas(h):EGFR(h):CD51(h):beta3-integrin(h):Src(h) (binding) | TGC(h) + beta3-integrin(h) <==> TGC(h):beta3-integrin(h) (binding) | beta3-integrin(h) + fibronectin(m.s.) <==> beta3-integrin(h):fibronectin(m.s.) (binding) | beta3-integrin(h) + Fibronectin-p42(m.s.) <==> beta3-integrin(h):Fibronectin-p42(m.s.) (binding) | beta3-integrin(h) + CD51-isoform1(h) <==> beta3-integrin(h):CD51-isoform1(h) (binding) | ITGB3(h) --> beta3-integrin(h) (expression). | GP1BB(h) --> beta3-integrin(h) (binding) | ITGB3(h) --> beta3A-integrin(h) (expression). | ITGB3(h) --> beta3B-integrin(h) (expression). | ITGB3(h) --> beta3C-integrin(h) (expression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 125 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 346 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 397 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 478 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 585 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 680 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 773 | Phosphotyrosine. | Swiss-Prot 53.0 | 779 | Phosphothreonine; by PDPK1 and PKB/AKT1;in vitro. | Swiss-Prot 53.0 | 785 | Phosphotyrosine. | Swiss-Prot 53.0 | 773 | Phosphotyrosine (Syk;Src) | 8631894;15699036 | Phospho.ELM 6.0 | 785 | Phosphotyrosine (Syk;Src) | 8631894 | Phospho.ELM 6.0 | 779 | Phosphothreonine (PDK-1) | 10896934 | Phospho.ELM 6.0 | 777 | Phosphothreonine (PDK-1) | 10896934 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr17 |
Promoter: 42684707 - 42686707 | Agilent_014791 |
chr17 |
Promoter: 42684707 - 42686707 | GSE27584 |
chr17 |
Promoter: 42684707 - 42686707 | Agilent_014791_44K |