Entrez Gene

Basic Information
Gene ID	3690
Name	ITGB3

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.1959C>T; p.D653D; 17:47300523-47300523	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1959C>T; p.D653D; 17:47300523-47300523	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1923G>A; p.V641V; 17:47300487-47300487	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.62delC; p.A21fs*5; 17:47253923-47253923	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2357G>A; p.R786Q; 17:47310194-47310194	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.555G>A; p.K185K; 17:47284636-47284636	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1476G>A; p.W492*; 17:47292354-47292354	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1850C>T; p.P617L; 17:47299467-47299467	ovary	other; neoplasm	Substitution - Missense
c.332C>A; p.P111H; 17:47283520-47283520	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1850C>T; p.P617L; 17:47299467-47299467	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1232C>A; p.S411Y; 17:47291060-47291060	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1651G>A; p.D551N; 17:47292529-47292529	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1799T>A; p.L600Q; 17:47299416-47299416	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.852G>A; p.L284L; 17:47287144-47287144	skin	malignant_melanoma	Substitution - coding silent
c.364G>T; p.D122Y; 17:47284445-47284445	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.977C>T; p.S326F; 17:47289718-47289718	skin	malignant_melanoma	Substitution - Missense
c.1944G>C; p.R648R; 17:47300508-47300508	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1188C>G; p.F396L; 17:47291016-47291016	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.889G>A; p.G297R; 17:47287181-47287181	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.606C>T; p.P202P; 17:47284687-47284687	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.153G>C; p.W51C; 17:47274492-47274492	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.614A>C; p.D205A; 17:47284695-47284695	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1696G>A; p.G566S; 17:47299313-47299313	skin	malignant_melanoma	Substitution - Missense
c.175C>T; p.L59L; 17:47283363-47283363	skin	malignant_melanoma	Substitution - coding silent
c.1316C>T; p.S439F; 17:47292194-47292194	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.447C>T; p.S149S; 17:47284528-47284528	skin	malignant_melanoma	Substitution - coding silent
c.323A>G; p.Q108R; 17:47283511-47283511	skin	malignant_melanoma	Substitution - Missense
c.1463G>A; p.C488Y; 17:47292341-47292341	prostate	carcinoma	Substitution - Missense
c.1253G>A; p.G418E; 17:47291081-47291081	skin	malignant_melanoma	Substitution - Missense
c.1361A>C; p.Q454P; 17:47292239-47292239	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1184C>T; p.S395F; 17:47291012-47291012	skin	malignant_melanoma	Substitution - Missense
c.985A>G; p.N329D; 17:47289726-47289726	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.369G>A; p.S123S; 17:47284450-47284450	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.369G>A; p.S123S; 17:47284450-47284450	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1607G>A; p.S536N; 17:47292485-47292485	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1886C>T; p.T629I; 17:47299503-47299503	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1228A>G; p.K410E; 17:47291056-47291056	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1864G>A; p.D622N; 17:47299481-47299481	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1864G>A; p.D622N; 17:47299481-47299481	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.187C>T; p.R63C; 17:47283375-47283375	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.432G>A; p.M144I; 17:47284513-47284513	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1530C>T; p.D510D; 17:47292408-47292408	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1451G>A; p.G484E; 17:47292329-47292329	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1451G>A; p.G484E; 17:47292329-47292329	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.598G>A; p.E200K; 17:47284679-47284679	skin	malignant_melanoma	Substitution - Missense
c.598G>A; p.E200K; 17:47284679-47284679	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2245G>A; p.D749N; 17:47307581-47307581	skin	malignant_melanoma	Substitution - Missense
c.1264A>G; p.S422G; 17:47292142-47292142	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2248C>T; p.R750*; 17:47307584-47307584	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1690+1G>A; p.?; 17:47292569-47292569	large_intestine	carcinoma; adenocarcinoma	Unknown
c.2248C>T; p.R750*; 17:47307584-47307584	skin	malignant_melanoma	Substitution - Nonsense
c.2071G>A; p.V691I; 17:47302777-47302777	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1520C>T; p.S507F; 17:47292398-47292398	skin	malignant_melanoma	Substitution - Missense
c.2071G>A; p.V691I; 17:47302777-47302777	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1520C>T; p.S507F; 17:47292398-47292398	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2071G>A; p.V691I; 17:47302777-47302777	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.694G>T; p.E232*; 17:47286339-47286339	breast	carcinoma	Substitution - Nonsense
c.935C>A; p.T312N; 17:47287227-47287227	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.935C>A; p.T312N; 17:47287227-47287227	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.1497C>T; p.C499C; 17:47292375-47292375	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1770T>G; p.T590T; 17:47299387-47299387	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2249G>A; p.R750Q; 17:47307585-47307585	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2249G>A; p.R750Q; 17:47307585-47307585	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1514G>A; p.R505H; 17:47292392-47292392	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1573G>T; p.G525C; 17:47292451-47292451	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1957G>A; p.D653N; 17:47300521-47300521	skin	malignant_melanoma	Substitution - Missense
c.1155G>A; p.V385V; 17:47290983-47290983	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.204G>T; p.E68D; 17:47283392-47283392	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1236T>C; p.C412C; 17:47291064-47291064	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1027C>A; p.L343I; 17:47289768-47289768	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1027C>T; p.L343F; 17:47289768-47289768	skin	malignant_melanoma	Substitution - Missense
c.1344G>A; p.K448K; 17:47292222-47292222	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1539delC; p.R515fs*154; 17:47292417-47292417	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2073C>A; p.V691V; 17:47302779-47302779	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.240C>T; p.I80I; 17:47283428-47283428	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1510T>C; p.Y504H; 17:47292388-47292388	skin	malignant_melanoma	Substitution - Missense
c.2265A>G; p.K755K; 17:47307601-47307601	skin	malignant_melanoma	Substitution - coding silent
c.289G>A; p.D97N; 17:47283477-47283477	skin	malignant_melanoma	Substitution - Missense
c.1875G>A; p.E625E; 17:47299492-47299492	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.594C>T; p.A198A; 17:47284675-47284675	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1025A>G; p.N342S; 17:47289766-47289766	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.368C>T; p.S123L; 17:47284449-47284449	breast	carcinoma	Substitution - Missense
c.1769C>G; p.T590S; 17:47299386-47299386	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1990G>A; p.E664K; 17:47300554-47300554	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.506G>A; p.R169Q; 17:47284587-47284587	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2309A>G; p.N770S; 17:47310146-47310146	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1812C>T; p.R604R; 17:47299429-47299429	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1356C>T; p.I452I; 17:47292234-47292234	skin	malignant_melanoma	Substitution - coding silent
c.1812C>T; p.R604R; 17:47299429-47299429	pancreas	carcinoma	Substitution - coding silent
c.467G>T; p.S156I; 17:47284548-47284548	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2032G>T; p.A678S; 17:47302738-47302738	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2032G>T; p.A678S; 17:47302738-47302738	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2032G>T; p.A678S; 17:47302738-47302738	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2032G>T; p.A678S; 17:47302738-47302738	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2032G>T; p.A678S; 17:47302738-47302738	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2032G>T; p.A678S; 17:47302738-47302738	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2149C>T; p.P717S; 17:47307485-47307485	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1558G>A; p.V520I; 17:47292436-47292436	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.890G>A; p.G297E; 17:47287182-47287182	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.771C>A; p.V257V; 17:47286416-47286416	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.771C>A; p.V257V; 17:47286416-47286416	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1506G>A; p.E502E; 17:47292384-47292384	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1064C>T; p.T355I; 17:47290213-47290213	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1800G>A; p.L600L; 17:47299417-47299417	bone; tibia	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1459C>T; p.R487C; 17:47292337-47292337	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1513C>T; p.R505C; 17:47292391-47292391	skin	malignant_melanoma	Substitution - Missense
c.1531G>A; p.E511K; 17:47292409-47292409	skin	malignant_melanoma	Substitution - Missense
c.1132C>T; p.R378C; 17:47290960-47290960	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1132C>T; p.R378C; 17:47290960-47290960	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1533A>G; p.E511E; 17:47292411-47292411	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.480G>T; p.L160L; 17:47284561-47284561	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1533A>G; p.E511E; 17:47292411-47292411	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.700A>T; p.K234*; 17:47286345-47286345	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.1533A>G; p.E511E; 17:47292411-47292411	thyroid	other; neoplasm	Substitution - coding silent
c.1533A>G; p.E511E; 17:47292411-47292411	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1899C>A; p.A633A; 17:47299516-47299516	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1943delG; p.G649fs*20; 17:47300507-47300507	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.137G>A; p.S46N; 17:47274476-47274476	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1087T>A; p.S363T; 17:47290236-47290236	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2196C>T; p.L732L; 17:47307532-47307532	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1134T>C; p.R378R; 17:47290962-47290962	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1243C>G; p.L415V; 17:47291071-47291071	oesophagus	carcinoma	Substitution - Missense
c.2191C>G; p.L731V; 17:47307527-47307527	urinary_tract; bladder	carcinoma	Substitution - Missense
c.479T>C; p.L160P; 17:47284560-47284560	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2259C>A; p.F753L; 17:47307595-47307595	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1303G>T; p.E435*; 17:47292181-47292181	skin; extremity	malignant_melanoma	Substitution - Nonsense
c.1261-1G>T; p.?; 17:47292138-47292138	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.2327C>T; p.A776V; 17:47310164-47310164	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1132C>G; p.R378G; 17:47290960-47290960	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.474G>A; p.Q158Q; 17:47284555-47284555	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.355C>T; p.R119W; 17:47283543-47283543	skin	malignant_melanoma	Substitution - Missense
c.1083G>A; p.M361I; 17:47290232-47290232	skin; trunk	malignant_melanoma	Substitution - Missense
c.326T>G; p.V109G; 17:47283514-47283514	breast	carcinoma	Substitution - Missense
c.58C>T; p.L20L; 17:47253919-47253919	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1043G>A; p.S348N; 17:47290192-47290192	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1496G>C; p.C499S; 17:47292374-47292374	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.872T>C; p.I291T; 17:47287164-47287164	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.801T>C; p.D267D; 17:47287093-47287093	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.783G>A; p.K261K; 17:47287075-47287075	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1883_1884CC>AA; p.P628Q; 17:47299500-47299501	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.526C>A; p.R176R; 17:47284607-47284607	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.432G>C; p.M144I; 17:47284513-47284513	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.505C>A; p.R169R; 17:47284586-47284586	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2105A>C; p.K702T; 17:47302811-47302811	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2011C>T; p.L671F; 17:47300575-47300575	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2306A>G; p.N769S; 17:47310143-47310143	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.191G>C; p.C64S; 17:47283379-47283379	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.403G>A; p.D135N; 17:47284484-47284484	skin	malignant_melanoma	Substitution - Missense
c.236C>T; p.S79F; 17:47283424-47283424	skin	malignant_melanoma	Substitution - Missense
c.581C>T; p.S194F; 17:47284662-47284662	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.585A>C; p.P195P; 17:47284666-47284666	breast	carcinoma	Substitution - coding silent
c.1012G>A; p.E338K; 17:47289753-47289753	thyroid	carcinoma	Substitution - Missense
c.1977T>C; p.R659R; 17:47300541-47300541	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1029C>A; p.L343L; 17:47289770-47289770	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2254G>T; p.E752*; 17:47307590-47307590	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1543C>T; p.R515W; 17:47292421-47292421	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1451G>T; p.G484V; 17:47292329-47292329	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1766G>A; p.R589H; 17:47299383-47299383	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1766G>A; p.R589H; 17:47299383-47299383	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1545G>A; p.R515R; 17:47292423-47292423	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1766G>A; p.R589H; 17:47299383-47299383	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1545G>A; p.R515R; 17:47292423-47292423	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1545G>A; p.R515R; 17:47292423-47292423	thyroid	other; neoplasm	Substitution - coding silent
c.1766G>A; p.R589H; 17:47299383-47299383	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1766G>A; p.R589H; 17:47299383-47299383	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1766G>A; p.R589H; 17:47299383-47299383	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1156C>T; p.R386C; 17:47290984-47290984	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1080C>T; p.S360S; 17:47290229-47290229	skin	malignant_melanoma	Substitution - coding silent
c.569A>G; p.Y190C; 17:47284650-47284650	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.2317T>C; p.Y773H; 17:47310154-47310154	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1629G>A; p.T543T; 17:47292507-47292507	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.771C>T; p.V257V; 17:47286416-47286416	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.93T>C; p.C31C; 17:47274432-47274432	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.93T>C; p.C31C; 17:47274432-47274432	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1333G>A; p.V445M; 17:47292211-47292211	pancreas	carcinoma	Substitution - Missense
c.150C>T; p.A50A; 17:47274489-47274489	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.764C>A; p.A255D; 17:47286409-47286409	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1459C>A; p.R487S; 17:47292337-47292337	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1563C>T; p.C521C; 17:47292441-47292441	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2260G>A; p.A754T; 17:47307596-47307596	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2089G>A; p.E697K; 17:47302795-47302795	skin	malignant_melanoma	Substitution - Missense
c.222_226delCTGTG; p.C75fs*10; 17:47283410-47283414	stomach	carcinoma; diffuse_adenocarcinoma	Deletion - Frameshift
c.1789A>G; p.N597D; 17:47299406-47299406	breast	carcinoma	Substitution - Missense
c.1481G>A; p.G494E; 17:47292359-47292359	NS	malignant_melanoma	Substitution - Missense
c.1106T>G; p.L369R; 17:47290255-47290255	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1481G>A; p.G494E; 17:47292359-47292359	NS	malignant_melanoma	Substitution - Missense
c.1094A>G; p.N365S; 17:47290243-47290243	breast	carcinoma	Substitution - Missense
c.350G>A; p.R117Q; 17:47283538-47283538	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.454G>T; p.D152Y; 17:47284535-47284535	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.865G>A; p.A289T; 17:47287157-47287157	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.526C>T; p.R176W; 17:47284607-47284607	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.526C>T; p.R176W; 17:47284607-47284607	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.526C>T; p.R176W; 17:47284607-47284607	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2323G>A; p.E775K; 17:47310160-47310160	skin	malignant_melanoma	Substitution - Missense
c.1560C>T; p.V520V; 17:47292438-47292438	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent

The somatic mutations from COSMIC database