| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2149 |
Name | F2R |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for F2R |
| Links to the AnimalTFDB for F2R |
Regulation From TransFac database | PAR-1(h) --> Gi(v.s.) (activation) | PAR-1(h) --> Gq(v.s.) (activation) | PAR-1(h) --> Vav(h){pY} (increase of phosphorylation) | PAR-1(h) --> ZAP-70(h){pY} (increase of phosphorylation) | PAR-1(h) --> SLP-76(h){pY} (increase of phosphorylation) | PAR-1(h) --> IL8(h) (transactivation) | PAR-1(h) --> IKK(h){p} (increase of phosphorylation) | PAR-1(h) --> cytosolic phospholipase A2(h){p} (increase of phosphorylation) | PAR-1(h) --> FAK1(h){pY} (increase of phosphorylation) | PAR-1(h) --> arachidonic acid (increase of secretion) | PAR-1(h) --> ERK2(h){p} (increase of phosphorylation) | F2R(h) --> PAR-1(h) (expression). | F2R(h) --> PAR-1(h) (expression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 35 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 62 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 75 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 250 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 259 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 410 | Phosphothreonine | 8955127 | Phospho.ELM 6.0 | 425 | Phosphothreonine | 8955127 | Phospho.ELM 6.0 | 375 | Phosphoserine | 8955127 | Phospho.ELM 6.0 | 376 | Phosphoserine | 8955127 | Phospho.ELM 6.0 | 384 | Phosphoserine | 8955127 | Phospho.ELM 6.0 | 391 | Phosphoserine | 8955127 | Phospho.ELM 6.0 | 392 | Phosphoserine | 8955127 | Phospho.ELM 6.0 | 395 | Phosphoserine | 8955127 | Phospho.ELM 6.0 | 396 | Phosphoserine | 8955127 | Phospho.ELM 6.0 | 399 | Phosphoserine | 8955127 | Phospho.ELM 6.0 | 400 | Phosphoserine | 8955127 | Phospho.ELM 6.0 | 406 | Phosphoserine | 8955127 | Phospho.ELM 6.0 | 413 | Phosphoserine | 8955127 | Phospho.ELM 6.0 | 412 | Phosphoserine | 8955127 | Phospho.ELM 6.0 | 418 | Phosphoserine | 8955127 | Phospho.ELM 6.0 | 397 | Phosphotyrosine | 8955127 | Phospho.ELM 6.0 | 383 | Phosphotyrosine | 15023990 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr5 |
Promoter: 76046047 - 76048047 | Agilent_014791 |
chr5 |
Promoter: 76046047 - 76048047 | GoldenGate_Methylation_Cancer_Panel_I |
chr5 |
Promoter: 76046047 - 76048047 | GSE27584 |
chr5 |
Promoter: 76046047 - 76048047 | Agilent_014791_44K |
chr5 |
Promoter: 76046047 - 76048047 | PMID:16367923 |