Entrez Gene

Basic Information
Gene ID	2149
Name	F2R

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.1127C>T; p.S376F; 5:76733352-76733352	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.420C>A; p.Y140*; 5:76732645-76732645	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Nonsense
c.831C>A; p.V277V; 5:76733056-76733056	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.831C>A; p.V277V; 5:76733056-76733056	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1090T>A; p.C364S; 5:76733315-76733315	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.352C>A; p.P118T; 5:76732577-76732577	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.561C>T; p.Y187Y; 5:76732786-76732786	breast	carcinoma	Substitution - coding silent
c.1004C>T; p.A335V; 5:76733229-76733229	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1004C>T; p.A335V; 5:76733229-76733229	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.764A>G; p.H255R; 5:76732989-76732989	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.764A>G; p.H255R; 5:76732989-76732989	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.764A>G; p.H255R; 5:76732989-76732989	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.764A>G; p.H255R; 5:76732989-76732989	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.978C>A; p.F326L; 5:76733203-76733203	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.635C>T; p.S212F; 5:76732860-76732860	skin	malignant_melanoma	Substitution - Missense
c.494G>A; p.G165D; 5:76732719-76732719	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1267C>A; p.L423M; 5:76733492-76733492	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.532G>A; p.V178I; 5:76732757-76732757	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.194G>T; p.G65V; 5:76732419-76732419	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1258T>C; p.Y420H; 5:76733483-76733483	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.527G>T; p.R176L; 5:76732752-76732752	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.512G>T; p.G171V; 5:76732737-76732737	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1210A>G; p.M404V; 5:76733435-76733435	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.979G>A; p.G327R; 5:76733204-76733204	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.399C>T; p.V133V; 5:76732624-76732624	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.765T>C; p.H255H; 5:76732990-76732990	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1207T>G; p.L403V; 5:76733432-76733432	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.879C>A; p.I293I; 5:76733104-76733104	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.504G>A; p.W168*; 5:76732729-76732729	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.504G>A; p.W168*; 5:76732729-76732729	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.438G>T; p.T146T; 5:76732663-76732663	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1115A>G; p.Y372C; 5:76733340-76733340	skin	malignant_melanoma	Substitution - Missense
c.598C>T; p.R200W; 5:76732823-76732823	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.558G>A; p.M186I; 5:76732783-76732783	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.907G>T; p.A303S; 5:76733132-76733132	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.1119C>T; p.Y373Y; 5:76733344-76733344	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1119C>T; p.Y373Y; 5:76733344-76733344	pancreas	carcinoma	Substitution - coding silent
c.1119C>T; p.Y373Y; 5:76733344-76733344	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.167G>A; p.W56*; 5:76732392-76732392	skin	malignant_melanoma	Substitution - Nonsense
c.928C>T; p.R310W; 5:76733153-76733153	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1202G>T; p.G401V; 5:76733427-76733427	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.386_391delTGAAAA; p.M131_K132delMK; 5:76732611-76732616	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - In frame
c.1240A>G; p.N414D; 5:76733465-76733465	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1034C>A; p.T345N; 5:76733259-76733259	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.183A>C; p.K61N; 5:76732408-76732408	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.387G>A; p.L129L; 5:76732612-76732612	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.310_311delTT; p.F104fs*54; 5:76732535-76732536	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.789C>T; p.L263L; 5:76733014-76733014	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.354A>C; p.P118P; 5:76732579-76732579	thyroid	other; neoplasm	Substitution - coding silent
c.697G>T; p.G233W; 5:76732922-76732922	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.213_214AG>TT; p.L71_V72>FF; 5:76732438-76732439	lung; right_upper_lobe	carcinoma; adenocarcinoma	Complex - compound substitution
c.1176C>T; p.S392S; 5:76733401-76733401	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.980G>A; p.G327E; 5:76733205-76733205	skin	malignant_melanoma	Substitution - Missense
c.834C>G; p.F278L; 5:76733059-76733059	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1175C>T; p.S392F; 5:76733400-76733400	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.200C>T; p.T67I; 5:76732425-76732425	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.311T>A; p.F104Y; 5:76732536-76732536	skin	malignant_melanoma	Substitution - Missense
c.813C>A; p.F271L; 5:76733038-76733038	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.879C>G; p.I293M; 5:76733104-76733104	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1066T>C; p.C356R; 5:76733291-76733291	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.14G>T; p.R5L; 5:76716321-76716321	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.917G>T; p.S306I; 5:76733142-76733142	urinary_tract; bladder	carcinoma	Substitution - Missense
c.879C>T; p.I293I; 5:76733104-76733104	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.879C>T; p.I293I; 5:76733104-76733104	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.879C>T; p.I293I; 5:76733104-76733104	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.97G>A; p.A33T; 5:76732322-76732322	ovary	other; neoplasm	Substitution - Missense
c.1087A>C; p.S363R; 5:76733312-76733312	skin	malignant_melanoma	Substitution - Missense
c.745C>T; p.L249F; 5:76732970-76732970	pancreas	carcinoma	Substitution - Missense
c.148G>A; p.D50N; 5:76732373-76732373	skin	malignant_melanoma	Substitution - Missense
c.843G>A; p.V281V; 5:76733068-76733068	breast	carcinoma	Substitution - coding silent
c.292A>G; p.S98G; 5:76732517-76732517	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.562G>A; p.A188T; 5:76732787-76732787	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.761G>A; p.C254Y; 5:76732986-76732986	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.154T>C; p.Y52H; 5:76732379-76732379	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1274C>T; p.T425I; 5:76733499-76733499	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.900C>T; p.S300S; 5:76733125-76733125	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1164C>A; p.C388*; 5:76733389-76733389	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.250C>T; p.L84F; 5:76732475-76732475	breast	carcinoma	Substitution - Missense
c.258A>G; p.A86A; 5:76732483-76732483	liver	carcinoma	Substitution - coding silent
c.624G>A; p.M208I; 5:76732849-76732849	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.258A>G; p.A86A; 5:76732483-76732483	liver	carcinoma	Substitution - coding silent
c.266C>A; p.S89*; 5:76732491-76732491	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1095C>T; p.C365C; 5:76733320-76733320	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1021T>C; p.S341P; 5:76733246-76733246	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1053T>A; p.F351L; 5:76733278-76733278	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.236C>A; p.P79H; 5:76732461-76732461	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.978C>G; p.F326L; 5:76733203-76733203	breast	carcinoma	Substitution - Missense
c.493G>A; p.G165S; 5:76732718-76732718	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.354A>T; p.P118P; 5:76732579-76732579	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.793G>T; p.G265C; 5:76733018-76733018	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.978C>T; p.F326F; 5:76733203-76733203	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.238C>G; p.L80V; 5:76732463-76732463	breast	carcinoma	Substitution - Missense
c.1245G>T; p.L415L; 5:76733470-76733470	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.932C>A; p.A311D; 5:76733157-76733157	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.789C>G; p.L263L; 5:76733014-76733014	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.702A>G; p.V234V; 5:76732927-76732927	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.763C>T; p.H255Y; 5:76732988-76732988	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.998T>A; p.L333Q; 5:76733223-76733223	skin	malignant_melanoma	Substitution - Missense
c.982C>A; p.P328T; 5:76733207-76733207	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1120G>A; p.A374T; 5:76733345-76733345	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.544T>C; p.F182L; 5:76732769-76732769	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.786G>A; p.L262L; 5:76733011-76733011	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.253C>A; p.P85T; 5:76732478-76732478	breast	carcinoma	Substitution - Missense

The somatic mutations from COSMIC database