Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

102

Name

ADAM10

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for ADAM10
Links to the AnimalTFDB for ADAM10

Regulation From TransFac database

adam10(h) + Eve-1c(h) <==> adam10(h):Eve-1c(h) (binding)
adam10(h) + Eve-1d(h) <==> adam10(h):Eve-1d(h) (binding)
ADAM10(h) --> adam10(h) (expression).
APP(h) --adam10(h)--> alphaAPPs(h) + APP-C83(h) (processing)
N-cadherin(h) --adam10(h)--> N-cadherin-CTF1(h) + protein remnants (cleavage)
ADAM10(h) --> adam10(h) (expression).
APP770(h) --adam10(h)--> sAPP770alpha(h) + APP-C83(h) (cleavage)
HB-EGF(h) --adam10(h)--> HB-EGF-p16.4(h) + protein remnants (cleavage)
HB-EGF(h) --adam10(h)--> HB-EGF-p15(h) + protein remnants (cleavage)

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

267N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
278N-linked (GlcNAc...).Swiss-Prot 53.0
439N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
551N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr15

Promoter: 56828969 - 56830969Agilent_014791

chr15

Promoter: 56828969 - 56830969GSE27584

chr15

Promoter: 56828969 - 56830969Agilent_014791_44K


')