Entrez Gene

Epithelial-Mesenchymal Transition gene database (dbEMT) Home

General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information
Gene ID	51176
Name	LEF1
Gene Interactions:	Data from Pathway Commons database Physical Interaction Metabolic Interaction Signaling Interaction

Interaction Type	Interactor	Data Source
Physical Interaction [Top]
in same component	AES	NCI_NATURE;
in same component	CDX1	NCI_NATURE;
in same component	CTNNB1	IMID;
in same component	CTNNB1	NCI_NATURE;
in same component	HDAC1	NCI_NATURE;
in same component	MITF	IMID;
in same component	MYB	NCI_NATURE;
in same component	NLK	CELL_MAP;
in same component	PITX2	NCI_NATURE;
in same component	TCF7	IMID;
in same component	TLE1	NCI_NATURE;
in same component	TLE2	NCI_NATURE;
interacts with	CDX1	CELL_MAP;
interacts with	CTNNB1	BIOGRID;
interacts with	CTNNB1	CELL_MAP;
interacts with	DACT1	BIOGRID;
interacts with	DAZAP2	BIOGRID;
interacts with	E2F1	BIOGRID;
interacts with	EP300	BIOGRID;
interacts with	HDAC1	BIOGRID;
interacts with	Kpna1	BIOGRID;
interacts with	Kpna2	BIOGRID;
interacts with	MITF	BIOGRID;
interacts with	MYB	BIOGRID;
interacts with	NLK	BIOGRID;
interacts with	NLK	CELL_MAP;
interacts with	NOTCH1	BIOGRID;
interacts with	PIAS4	BIOGRID;
interacts with	Pias4	CELL_MAP;
interacts with	RUVBL1	BIOGRID;
interacts with	SMAD2	BIOGRID;
interacts with	SMAD2	CELL_MAP;
interacts with	SMAD4	BIOGRID;
interacts with	SMAD4	CELL_MAP;
interacts with	SMAD7	BIOGRID;
interacts with	THOC4	BIOGRID;
interacts with	TLE1	BIOGRID;
interacts with	UBTF	BIOGRID;
interacts with	ZBTB3	BIOGRID;

Interaction Type	Interactor	Data Source
Metabolic Interaction [Top]
metabolic catalysis	CTNNB1	NCI_NATURE;
metabolic catalysis	LEF1	NCI_NATURE;
metabolic catalysis	PITX2	NCI_NATURE;

Interaction Type	Interactor	Data Source
Signaling Interaction [Top]
reacts with	AES	NCI_NATURE;
reacts with	CDX1	NCI_NATURE;
reacts with	CTNNB1	IMID;
reacts with	CTNNB1	NCI_NATURE;
reacts with	HDAC1	NCI_NATURE;
reacts with	LEF1	IMID;
reacts with	LEF1	NCI_NATURE;
reacts with	MITF	IMID;
reacts with	MYB	NCI_NATURE;
reacts with	PITX2	NCI_NATURE;
reacts with	TCF7	IMID;
reacts with	TLE1	NCI_NATURE;
reacts with	TLE2	NCI_NATURE;
state change	NLK	CELL_MAP;

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