| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | From Entrez database: 51176 |
|---|---|
Gene ID | 51176 |
Name | LEF1 |
Synonym | LEF-1|TCF10|TCF1ALPHA|TCF7L3;lymphoid enhancer-binding factor 1;LEF1;lymphoid enhancer-binding factor 1 |
Definition | T cell-specific transcription factor 1-alpha|TCF1-alpha |
Position | 4q23-q25 |
Gene Type | protein-coding |
Pathways and Diseases | From KEGG database |
Pathway | Wnt signaling pathway;KEGG PATHWAY;hsa04310 |
Pathway | Arrhythmogenic right ventricular cardiomyopathy (ARVC);KEGG PATHWAY;hsa05412 |
Pathway | Melanogenesis;KEGG PATHWAY;hsa04916 |
Pathway | inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages;PID BioCarta;100152 |
Pathway | Adherens junction;KEGG PATHWAY;hsa04520 |
Pathway | multi-step regulation of transcription by pitx2;PID BioCarta;100074 |
Pathway | Alzheimer disease-presenilin pathway;PANTHER;P00004 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | Cadherin signaling pathway;PANTHER;P00012 |
Pathway | Endometrial cancer;KEGG PATHWAY;hsa05213 |
Pathway | Prostate cancer;KEGG PATHWAY;hsa05215 |
Pathway | Colorectal cancer;KEGG PATHWAY;hsa05210 |
Pathway | Basal cell carcinoma;KEGG PATHWAY;hsa05217 |
Pathway | Regulation of Wnt-mediated beta catenin signaling and target gene transcription;PID Curated;200106 |
Pathway | C-MYB transcription factor network;PID Curated;200130 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Thyroid cancer;KEGG PATHWAY;hsa05216 |
Pathway | Acute myeloid leukemia;KEGG PATHWAY;hsa05221 |
Disease | other metabolic traits;GAD |
Disease | Sebaceous tumors, somatic;OMIM |
Disease | METABOLIC;GAD |
Disease | Other metabolic traits;NHGRI |
External Links | |
Links to Entrez Gene | 51176 |
Links to all GeneRIF Items | 51176 |
Sequence Information | |
Nucleotide Sequence | >51176 : length: 3620 AGCGCCGGCGAGGCGCGGGAGGAGGAGAAGCAGTGGGGAGGCGCAGCCGCTCACCTGCGG GGCAGGGCGCGGAGGAGGGACCCGGGCTGCGCGCTCTCGGGCCGAGGAACCAGGACGCGC CCGGAGCCTCGCACGCGGCCAAGCTCGGGGCGTCCCCTCCCCTCGGCCGGGCGAACTCAA GGGGCGCAGCTCTTTGCTTTGACAGAGCTGGCCGGCGGAGGCGTGCAGAGCGGCGAGCCG GCGAGCCAGGCTGAGAAACTCGAGCCGGGAACAAAGAGGGGTCGGACTGAGTGTGTGTGT CGGCTCGAGCTCCGGGCAGAGGCATTTGGGCCCGAGGCCCCCGCTGTGACTCCCCGAGAC TCCGCAGTGCCCTCCACTGCGGAGTCCCCGCGCTTGCCGGCAAAAACTTTATTCTTGGCA AACTTCTCTTTCTCTTCCCCTCCTCCTCGGCCCCCATCTTCTGCTCCTCCTCCTTCTCTA GCAGATTAAATGAGCCTCGAGAAGAAAAACCGAAGCGAAAGGGAAGAAAATAAGAAGATC TAAAACGGACATCTCCAGCGTGGGTGGCTCCTTTTTCTTTTTCTTTTTTTCCCACCCTTC AGGAAGTGGACGTTTCGTTATCTTCTGATCCTTGCACCTTCTTTTGGGGCAAACGGGGCC CTTCTGCCCAGATCCCCTCTCTTTTCTCGGAAAACAAACTACTAAGTCGGCATCCGGGGT AACTACAGTGGAGAGGGTTTCCGCGGAGACGCGCCGCCGGACCCTCCTCTGCACTTTGGG GAGGCGTGCTCCCTCCAGAACCGGCGTTCTCCGCGCGCAAATCCCGGCGACGCGGGGTCG CGGGGTGGCCGCCGGGGCAGCCTCGTCTAGCGCGCGCCGCGCAGACGCCCCCGGAGTCGC CAGCTACCGCAGCCCTCGCCGCCCAGTGCCCTTCGGCCTCGGGGGCGGGCGCCTGCGTCG GTCTCCGCGAAGCGGGAAAGCGCGGCGGCCGCCGGGATTCGGGCGCCGCGGCAGCTGCTC CGGCTGCCGGCCGGCGGCCCCGCGCTCGCCCGCCCCGCTTCCGCCCGCTGTCCTGCTGCA CGAACCCTTCCAACTCTCCTTTCCTCCCCCACCCTTGAGTTACCCCTCTGTCTTTCCTGC TGTTGCGCGGGTGCTCCCACAGCGGAGCGGAGATTACAGAGCCGCCGGGATGCCCCAACT CTCCGGAGGAGGTGGCGGCGGCGGGGGGGACCCGGAACTCTGCGCCACGGACGAGATGAT CCCCTTCAAGGACGAGGGCGATCCTCAGAAGGAAAAGATCTTCGCCGAGATCAGTCATCC CGAAGAGGAAGGCGATTTAGCTGACATCAAGTCTTCCTTGGTGAACGAGTCTGAAATCAT CCCGGCCAGCAACGGACACGAGGTGGCCAGACAAGCACAAACCTCTCAGGAGCCCTACCA CGACAAGGCCAGAGAACACCCCGATGACGGAAAGCATCCAGATGGAGGCCTCTACAACAA GGGACCCTCCTACTCGAGTTATTCCGGGTACATAATGATGCCAAATATGAATAACGACCC ATACATGTCAAATGGATCTCTTTCTCCACCCATCCCGAGAACATCAAATAAAGTGCCCGT GGTGCAGCCATCCCATGCGGTCCATCCTCTCACCCCCCTCATCACTTACAGTGACGAGCA CTTTTCTCCAGGATCACACCCGTCACACATCCCATCAGATGTCAACTCCAAACAAGGCAT GTCCAGACATCCTCCAGCTCCTGATATCCCTACTTTTTATCCCTTGTCTCCGGGTGGTGT TGGACAGATCACCCCACCTCTTGGCTGGCAAGGTCAGCCTGTATATCCCATCACGGGTGG ATTCAGGCAACCCTACCCATCCTCACTGTCAGTCGACACTTCCATGTCCAGGTTTTCCCA TCATATGATTCCCGGTCCTCCTGGTCCCCACACAACTGGCATCCCTCATCCAGCTATTGT AACACCTCAGGTCAAACAGGAACATCCCCACACTGACAGTGACCTAATGCACGTGAAGCC TCAGCATGAACAGAGAAAGGAGCAGGAGCCAAAAAGACCTCACATTAAGAAGCCTCTGAA TGCTTTTATGTTATACATGAAAGAAATGAGAGCGAATGTCGTTGCTGAGTGTACTCTAAA AGAAAGTGCAGCTATCAACCAGATTCTTGGCAGAAGGTGGCATGCCCTCTCCCGTGAAGA GCAGGCTAAATATTATGAATTAGCACGGAAAGAAAGACAGCTACATATGCAGCTTTATCC AGGCTGGTCTGCAAGAGACAATTATGGTAAGAAAAAGAAGAGGAAGAGAGAGAAACTACA GGAATCTGCATCAGGTACAGGTCCAAGAATGACAGCTGCCTACATCTGAAACATGGTGGA AAACGAAGCTCATTCCCAACGTGCAAAGCCAAGGCAGCGACCCCAGGACCTCTTCTGGAG ATGGAAGCTTGTTGAAAACCCAGACTGTCTCCACGGCCTGCCCAGTCGACCCCAAAGGAA CACTGACATCAATTTTACCCTGAGGTCACTGCTAGAGACGCTGATCCATAAAGACAATCA CTGCCAACCCCTCTTTCGTCTACTGCAAGAGCCAAGTTCCAAAATAAAGCATAAAAAGGT TTTTTAAAAGGAAATGTAAAAGCACATGAGAATGCTAGCAGGCTGTGGGGCAGCTGAGCA GCTTTTCTCCCCTCATATCTGCGTGCACTTCCCAGAGCATCTTGCATCCAAACCTGTAAC CTTTCGGCAAGGACGGTAACTTGGCTGCATTTGCCTGTCATGCGCAACTGGAGCCAGCAA CCAGCACATCCATCAGCACCCCAGTGGAGGAGTTCATGGAAGAGTTCCCTCTTTGTTTCT GCTTCATTTTTCTTTCTTTTCTTTTCTCCTAAAGCTTTTATTTAACAGTGCAAAAGGATC GTTTTTTTTTGCTTTTTTAAACTTGAATTTTTTTAATTTACACTTTTTAGTTTTAATTTT CTTGTATATTTTGCTAGCTATGAGCTTTTAAATAAAATTGAAAGTTCTGGAAAAGTTTGA AATAATGACATAAAAAGAAGCCTTCTTTTTCTGAGACAGCTTGTCTGGTAAGTGGCTTCT CTGTGAATTGCCTGTAACACATAGTGGCTTCTCCGCCCTTGTAAGGTGTTCAGTAGAGCT AAATAAATGTAATAGCCAAACCCACTCTGTTGGTAGCAATTGGCAGCCCTATTTCAGTTT ATTTTTTCTTCTGTTTTCTTCTTTTCTTTTTTTAAACAGTAAACCTTAACAGATGCGTTC AGCAGACTGGTTTGCAGTGAATTTTCATTTCTTTCCTTATCACCCCCTTGTTGTAAAAAG CCCAGCACTTGAATTGTTATTACTTTAAATGTTCTGTATTTGTATCTGTTTTTATTAGCC AATTAGTGGGATTTTATGCCAGTTGTTAAAATGAGCATTGATGTACCCATTTTTTAAAAA AGCAAGGCACAGCCTTTGCCCAAAACTGTCATCCTAACGTTTGTCATTCCAGTTTGAGTT AATGTGCTGAGCATTTTTTTAAAAGAAGCTTTGTAATAAAACATTTTTAAAAATTGTCAT TTAAAAAAAAAAAAAAAAAA |