| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | From Entrez database: 8660 |
|---|---|
Gene ID | 8660 |
Name | IRS2 |
Synonym | IRS-2;insulin receptor substrate 2;IRS2;insulin receptor substrate 2 |
Definition | - |
Position | 13q34 |
Gene Type | protein-coding |
Pathways and Diseases | From KEGG database |
Pathway | Adipocytokine signaling pathway;KEGG PATHWAY;hsa04920 |
Pathway | Insulin signaling pathway;KEGG PATHWAY;hsa04910 |
Pathway | IL4-mediated signaling events;PID Curated;200018 |
Pathway | IL2-mediated signaling events;PID Curated;200082 |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
Pathway | IGF1 pathway;PID Curated;200084 |
Pathway | EPO signaling pathway;PID Curated;200157 |
Pathway | Signaling by Insulin receptor;Reactome;REACT:498 |
Pathway | Signaling by FGFR;Reactome;REACT:9470 |
Pathway | Insulin/IGF pathway-protein kinase B signaling cascade;PANTHER;P00033 |
Pathway | Interleukin signaling pathway;PANTHER;P00036 |
Pathway | Type II diabetes mellitus;KEGG PATHWAY;hsa04930 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade;PANTHER;P00032 |
Pathway | Aldosterone-regulated sodium reabsorption;KEGG PATHWAY;hsa04960 |
Pathway | Signaling events regulated by Ret tyrosine kinase;PID Curated;200058 |
Disease | longevity;GAD |
Disease | Insulin Resistance;GAD |
Disease | diabetes, type 2;GAD |
Disease | polycystic ovarian syndrome;GAD |
Disease | CANCER;GAD |
Disease | METABOLIC;GAD |
Disease | obesity;GAD |
Disease | AGING;GAD |
Disease | Diabetes mellitus, noninsulin-dependent;OMIM |
Disease | colorectal cancer;GAD |
External Links | |
Links to Entrez Gene | 8660 |
Links to all GeneRIF Items | 8660 |
Sequence Information | |
Nucleotide Sequence | >8660 : length: 7014 CGGGGACCGCGACGAGCCCGGGTCGCCGTTGGCAGCAGCAGCAGCAACACCAGCAGCAGC AGCAGCCCCGGCGGCGGCGCGGACCCCGAGCGCCCGGGCGCACCCCGGCTTCCCGGAGCG CGACGCGGCGGCAGCAGCCCCGGTGCGGCCGCGCGCGCCTTAGGCTCGGCCCCGCGGCTC GGGGACCCCGACTCCCGGCCCAGCGAGCGCGTCCCCCGGCGCCGCCCGAGAGCCCGAGGA GGCAGCGGCCGCAGGCAGCCGGGGAGGGGGGCGGCCACCGCCCGCGCCGGGCATCCTCAG GAGCCCCAGAGCGCGGAGGGCGCGGCGCCGCCGAGCGGTGCTGGCCCCCGCGGGCCTCCC CGGACCTTCCCCACCGCCTGGGCCCGAGGGACGCGTGATCGGGCGGGCGGCCGGGCGCAA GGGTGGGAGGGAGCCGCCCCCGCCCGCGCCCCCTCCGCCCCTCGCCCCAACCCCTGGGCG CCGGGCCCGGGCCGCGCGGCCTGAAGCGCCCGCGATGGCGAGCCCGCCGCGGCACGGGCC GCCCGGGCCGGCGAGCGGAGACGGCCCCAACCTCAACAACAACAACAACAACAACAACCA CAGCGTGCGCAAGTGCGGCTACCTGCGCAAGCAGAAGCATGGCCACAAGCGCTTCTTCGT GCTGCGCGGACCCGGCGCGGGCGGCGACGAGGCGACGGCGGGCGGGGGGTCGGCGCCGCA ACCGCCGCGGCTCGAGTACTACGAGAGCGAGAAAAAGTGGCGGAGCAAGGCAGGCGCGCC GAAACGGGTGATCGCTCTCGACTGCTGCCTGAACATCAACAAGCGCGCCGACGCCAAGCA CAAGTACCTGATCGCCCTCTACACCAAGGACGAGTACTTCGCCGTGGCCGCCGAGAACGA GCAGGAGCAGGAGGGCTGGTACCGCGCGCTCACCGACCTGGTCAGCGAGGGCCGCGCGGC CGCCGGAGACGCGCCCCCCGCCGCCGCGCCCGCCGCGTCCTGCAGCGCCTCCCTGCCCGG CGCCCTGGGCGGCTCTGCCGGCGCCGCCGGGGCCGAGGACAGCTACGGGCTGGTGGCTCC CGCCACGGCCGCCTACCGTGAGGTGTGGCAGGTGAACCTGAAGCCCAAGGGTCTGGGCCA GAGCAAGAACCTGACGGGGGTGTACCGTCTGTGCCTGTCTGCGCGCACCATCGGCTTCGT GAAGCTCAACTGCGAGCAGCCGTCGGTGACGCTGCAGCTCATGAACATCCGCCGCTGCGG CCACTCGGACAGCTTCTTCTTCATCGAGGTGGGCCGCTCGGCCGTCACAGGCCCCGGCGA GCTGTGGATGCAGGCGGACGACTCGGTGGTGGCGCAGAACATCCACGAGACCATCCTGGA GGCCATGAAGGCGCTCAAGGAGCTCTTCGAGTTCCGGCCGCGCAGTAAGAGCCAATCGTC GGGGTCGTCGGCCACGCACCCCATCAGCGTCCCCGGCGCGCGCCGCCACCACCACCTGGT CAACCTGCCCCCCAGCCAGACGGGCCTGGTGCGCCGCTCGCGCACCGACAGCCTGGCCGC CACCCCGCCGGCGGCCAAGTGCAGCTCGTGCCGGGTGCGCACCGCCAGCGAGGGCGACGG CGGCGCGGCGGCGGGAGCGGCGGCCGCGGGCGCCAGGCCGGTGTCGGTGGCTGGGAGCCC CCTGAGCCCCGGGCCGGTGCGCGCGCCCCTGAGCCGCTCGCACACCCTGAGCGGCGGCTG CGGCGGCCGCGGGAGCAAGGTGGCGCTGCTGCCGGCAGGGGGCGCGCTGCAACACAGCCG CTCCATGTCCATGCCCGTGGCGCACTCGCCGCCCGCCGCCACCAGCCCCGGCTCCCTGTC GTCCAGCAGCGGCCACGGCTCGGGCTCCTACCCGCCGCCGCCCGGCCCGCACCCGCCTCT GCCGCATCCGCTGCACCACGGCCCCGGCCAGCGGCCCTCCAGCGGCAGCGCCTCCGCCTC GGGCTCCCCCAGCGACCCCGGCTTCATGTCCCTGGACGAGTACGGCTCCAGCCCAGGCGA CCTGCGCGCCTTCTGCAGCCACCGAAGCAACACGCCCGAGTCCATCGCGGAGACGCCCCC GGCCCGAGACGGCGGCGGCGGCGGTGAGTTCTACGGGTACATGACCATGGACAGGCCCCT GAGCCACTGTGGCCGCTCCTACCGCCGGGTCTCGGGGGACGCGGCCCAGGACCTGGACCG AGGGCTGCGCAAGAGGACCTACTCCCTGACCACGCCAGCCCGGCAGCGGCCGGTGCCCCA GCCCTCCTCTGCCTCGCTGGATGAATACACCCTGATGCGGGCCACCTTCTCGGGCAGCGC GGGCCGCCTCTGCCCGTCCTGCCCCGCGTCCTCTCCCAAGGTGGCCTACCACCCCTACCC AGAGGACTACGGAGACATCGAGATCGGCTCCCACAGGAGCTCCAGCAGCAACCTGGGGGC AGACGACGGCTACATGCCCATGACGCCCGGCGCGGCCCTCGCGGGCAGTGGGAGCGGCAG CTGCAGGAGCGACGACTACATGCCCATGAGCCCCGCCAGCGTGTCCGCCCCCAAGCAGAT CTTGCAGCCCAGGGCCGCCGCCGCCGCCGCCGCCGCCGTGCCTTCTGCGGGGCCTGCGGG GCCAGCACCCACCTCTGCGGCGGGCAGGACATTCCCGGCGAGCGGGGGCGGCTACAAGGC CAGCTCGCCCGCCGAGAGCTCCCCCGAGGACAGTGGGTACATGCGCATGTGGTGCGGTTC CAAGCTGTCCATGGAGCATGCAGATGGCAAGCTGCTGCCCAACGGGGACTACCTCAACGT GTCCCCCAGCGACGCGGTCACCACGGGCACCCCGCCCGACTTCTTCTCCGCAGCCCTGCA CCCCGGCGGGGAGCCGCTCAGGGGCGTTCCCGGCTGCTGCTACAGCTCCTTGCCCCGCTC CTACAAGGCCCCCTACACCTGTGGCGGGGACAGCGACCAGTACGTGCTCATGAGCTCCCC CGTGGGGCGCATCCTGGAGGAGGAGCGTCTGGAGCCTCAGGCCACGCCAGGGCCCAGCCA GGCGGCCAGCGCCTTCGGGGCCGGCCCCACGCAGCCCCCTCACCCTGTAGTGCCTTCGCC CGTGCGGCCTAGCGGCGGCCGCCCGGAGGGCTTCTTGGGCCAGCGCGGCCGGGCGGTGAG GCCCACGCGCCTGTCCCTGGAGGGGCTGCCCAGCCTGCCCAGCATGCACGAGTACCCACT GCCACCGGAGCCCAAGAGCCCCGGCGAGTACATCAACATCGACTTTGGCGAGCCCGGGGC CCGCCTGTCGCCGCCCGCGCCTCCCCTGCTGGCGTCGGCGGCCTCGTCCTCCTCGCTCTT GTCCGCCAGCAGCCCGGCCTCGTCGCTGGGCTCAGGCACCCCGGGCACCAGCAGCGACAG CCGGCAGCGGTCTCCGCTCTCCGACTACATGAACCTCGACTTCAGCTCCCCCAAGTCTCC TAAGCCGGGCGCCCCGAGCGGCCACCCCGTGGGCTCCTTGGACGGCCTCCTGTCCCCCGA GGCCTCCTCCCCGTATCCGCCGTTGCCCCCGCGTCCGTCCGCGTCCCCGTCGTCGTCTCT GCAGCCGCCGCCACCGCCGCCGGCCCCGGGGGAGCTGTACCGCCTGCCCCCCGCCTCGGC CGTTGCCACCGCCCAGGGCCCGGGCGCCGCCTCATCGTTGTCCTCGGACACCGGGGACAA TGGTGACTACACCGAGATGGCTTTTGGTGTGGCCGCCACCCCGCCGCAACCTATCGCGGC CCCCCCGAAGCCAGAAGCTGCCCGCGTGGCCAGCCCGACGTCGGGCGTGAAGAGGCTGAG CCTCATGGAGCAGGTGTCGGGAGTCGAGGCCTTCCTGCAGGCCAGCCAGCCCCCGGACCC CCACCGCGGCGCCAAGGTCATCCGCGCAGACCCGCAGGGGGGCCGCCGCCGCCACAGTTC CGAGACCTTCTCCTCCACCACGACGGTCACCCCCGTGTCCCCGTCCTTCGCCCACAACCC CAAGCGCCACAACTCGGCCTCCGTGGAAAATGTCTCTCTCAGGAAAAGCAGCGAGGGCGG CGTGGGTGTCGGCCCTGGAGGGGGCGACGAGCCGCCCACCTCCCCACGACAGTTGCAGCC GGCGCCCCCTTTGGCACCGCAGGGCCGGCCGTGGACCCCGGGTCAGCCCGGGGGCTTGGT CGGTTGTCCTGGGAGCGGTGGATCGCCCATGCGCAGAGAGACCTCTGCCGGCTTCCAGAA TGGTCTCAACTACATCGCCATCGACGTGAGGGAGGAGCCCGGGCTGCCACCCCAGCCGCA GCCGCCGCCGCCGCCGCTTCCTCAGCCGGGAGACAAGAGCTCCTGGGGCCGGACCCGAAG CCTCGGGGGTCTCATCAGCGCTGTGGGCGTCGGCAGCACCGGCGGCGGGTGCGGGGGGCC GGGTCCCGGTGCCCTGCCCCCTGCCAACACCTACGCCAGCATTGACTTCTTGTCCCACCA CTTGAAGGAGGCCACCATCGTGAAAGAGTGAAGATCTGTCTGGCTTTATCACCAGGATGT CACATGTCAGAGAGTATCATTAAAAGAAGACGCTCAGCACTGTTTCAGCCCGAAGCTGCT TGCAGTTTTCTTTTGGATCTGAGCAATGACTGTGTTTGGAAACATCTGTGGACTCTGTTA GATGAGGCACCAACAAGGCAAGGTCACCTGCCTCTTTCCCTTGTTCCCGGATGGGGCATT CATCATTGTGCTGTTTGCGTTTTGTTTTGTTTTGTTTTAACAAAATTAGCTGAAGAAGTT ATTCTCAAGAAAATTGGATGTTTTCATTGGCCTTCTTAAATTGTGGCCAGTGTCTTTTAA TTTCTTCTTCTTTTCCTTTTGGCAAAGCAGATATAACCCTCAGCATGCTAGGAGAGTGCA CCCGTACCTATGGAAGTGGTAAAATCTGGTATTTACTGGCTTACACTCAAAACGACCACA GTCCTACCTCAGTTCAAGGTAAAGCCGGATTTCCGTGGCGGGGGTCCCACAGGACCTCCT GTAGTAGCCCCTGCGCTGTGTGTCTGGAGCGCGGTCCTCGGCCTTATTGAAATGGTCCAA GTAGACAGCTGCTTGTTGGATTCCAGTGCAGGTACCTGCGATGTTTACGTCCACACCGAG CCCAGTGTGGGACTGACATTTCTCAATGGAAGTGAAATTTGGGATTGGACTTTGAAGACG GATTACTAAATAATAATTATTATATGTAACTGAAGCAACCTACTTTTGAAAATCAACTGT ATTGGGTAGTGGGAGGTGGGAGGGAAGGGCTTTGGGAAGGGGATGAATATCTCTTTTTAC CTTTAACAGACTTGTTTAATCTTCTCGATGTAGATGTTTATGTAGGTACTTCACATTGCA AACGCCTTTTATTCTATTTACAAGCTCAGATGTCTCTGCTCTCCTGAATCTTGGGCATGC CTTTCTGTAACCAAAAATCCCTGTAGGCGTGCTAGCAATTCCAGGGTGGTCCGGGTTTGG CAGATTTGATTTTTAAAAAACGTATTATCTTTAATAAAATGTTATTATGTCAACCAGTGA GGCTGCCCTGAACAAAAAAAACAAAAAGAAAAAAAAAAAAGGAAAGAAAGAAACTGATAA AAAGAGGCATTCCAGCCCCTATGTTATTGATGGAAAAAGAAAAAGAAGAAAAGCAATCTC GCAGTACATGTTACTTGTCGAAAAAATTCCGGACAAGACTACCCTTGTTTTATGTTTTCA GTATTCTGAAAATACCAGTGTGTGGCAGTTCTCGCAGATGTTACCTAAAACTGCTGAACT TGACCGGCAGAATGTTCTGCCGTTTTCTGCTCCCTCGACACTTGATTGGAGGGCTGTCGA CCTCTCCTCCCGTGGGGGCTTCCCCAGTGCCTATCTTCTCTGATAGTCATGGAGAGGTTA CACTAATTCATTGGAGATGTAAGTTGTTGGTTTTGTTTTGTTTTGTTTTTAGAAAAATAT ATATAAATATATAATAGATATCTATCGCTATAGAATAATGCATTAATAAAATGAGGCTTT TTTAGAGGAAGACCAAAAAATTCAATGTCTTAAAAATATATTTAATGGCAATGCAAAAGT CTTCCTGCTTCCGTGCTGAACTTTAGAACAGAGGATTGTATTGCAAGACAAAGTTGAATG TAAAGTGATCTCCCTGAACATTTTTAAGGTTTTACTTTTCTGAAATTATACATCACAGCA GTGCATAGGCCATATAATGTTAGCTGGAAGGTCAATTTCAGTGTATGATATACTTTATTA AGATGTATAAAAATCCTGAAGTTTTTATTTAGTTTTGGGAATAGGCATCAATGGGTGGTA TTTGCTTTGTAACTCCCCCCAGGTACGATAGGGACTGAATATGGACCCTGCTGAAAGCAG TGTATTGACGCATATTTAACTCGCCCTCTATCCGTAGAGTAGTCATGACACTATACAGAT GGTTCGTGTTCATACTGCAGCTTAAAACAAGCAAAATACACAGATGATAATATGCTAAAT TTTCCTCTATCCTGTACATTTCACAAAAAGGCATATGCAATATTTACATTTTTAATTTAG TTTACAGAATGGAACCAAAATGTATAAATGTTATGTTTGCTAAAACTTCACAATGTATAT TGGGTCTTTGTACATTTTGCCTGACTTACCTTAAATTTAAAATATTTTTTGCTATATAAA CTTTAACAGTTATTAAACAGTGTTTTCTTTTTGGGTACGTATTGTTTCTGGATATCAAGA TGTTAAATATATTTCTTGCTATTGTGATATGACAAGAGACTTAACTTATCTTGCTCTGTC TTCCACTGTACACGCTGTATATAGGGGTCAATGTGATGCTGCTGGAGACGAGAATAAACT GGACTAGAATAGTGCATTGTATTTAGTCTGTATTGATCATGGATGCCCTCCTTAATAGCC ATATGCAATAAAATAAAGTACATTATTTATGAAATGAAAAAAAAAAAAAAAAAA |