Entrez Gene

Basic Information
Gene ID	8881
Name	CDC16
Synonymous	cell division cycle 16;CDC16;cell division cycle 16
Definition	CDC16Hs\|anaphase-promoting complex subunit 6\|anaphase-promoting complex, subunit 6\|cell division cycle 16 homolog\|cell division cycle protein 16 homolog\|cyclosome subunit 6
Position	13q34
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
Cdc16(h) + ATP --cyclinB1(h):Cdk1(h):Cks1(h)--> Cdc16(h){pS559} + ADP (phosphorylation)
Cdc16(h) + ATP --cyclinB1(h):Cdk1(h):Cks1(h)--> Cdc16(h){pT580} + ADP (phosphorylation)
Cdc16(h) + ATP --plk1(m){p}--> Cdc16(h){p} + ADP (phosphorylation)
Cdc16(h) + Smad3(m.s.) <==> Cdc16(h):Smad3(m.s.) (binding)
Smad2(m.s.) + Cdc16(h) <==> Smad2(m.s.):Cdc16(h) (binding)
Cdc16(h) + SnoN(h) <==> Cdc16(h):SnoN(h) (binding)
Mps1(h) + Cdc16(h) + Cdc27(h) <==> Cdc27(h):Cdc16(h):Mps1(h) (binding)
Emi1(h) + APC1(h) + Cdc27(h) + Cdc16(h) <==> Emi1(h):APC1(h):Cdc27(h):Cdc16(h) (binding)
APC1(h) + APC11(h) + APC2(h) + APC4(h) + APC5(h) + APC7(h) + Cdc16(h) + Cdc23(h) + Emi1(h) + Fzr1(h) <==> APC1(h):APC2(h):APC4(h):APC5(h):Cdc16(h):APC7(h):Cdc23(h):APC11(h):Fzr1(h):Emi1(h) (binding)
Cdc16(h) + APC10(h) <==> Cdc16(h):APC10(h) (binding)
Cdc27(h) + Cdc16(h) <==> Cdc27(h):Cdc16(h) (binding)
CDC16(h) --> Cdc16(h) (expression).
CDC16(h) --> Cdc16(h) (expression).
CDC16(h) --> Cdc16-xbb2(h) (expression).
CDC16(h) --> Cdc16-xbb3(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
112	Phosphoserine.		Swiss-Prot 53.0
490	Phosphoserine.		Swiss-Prot 53.0
560	Phosphoserine.		Swiss-Prot 53.0
581	Phosphothreonine.		Swiss-Prot 53.0
595	Phosphoserine.		Swiss-Prot 53.0
599	Phosphothreonine.		Swiss-Prot 53.0
581	Phosphothreonine (CDK1)	14657031	Phospho.ELM 6.0
595	Phosphoserine	14657031	Phospho.ELM 6.0
599	Phosphothreonine	14657031	Phospho.ELM 6.0
560	Phosphoserine (CDK1)	14657031	Phospho.ELM 6.0
112	Phosphoserine	14657031	Phospho.ELM 6.0
490	Phosphoserine	14657031	Phospho.ELM 6.0

Transcription Factors [Top]