Entrez Gene

Basic Information
Gene ID	8881
Name	CDC16
Synonymous	cell division cycle 16;CDC16;cell division cycle 16
Definition	CDC16Hs\|anaphase-promoting complex subunit 6\|anaphase-promoting complex, subunit 6\|cell division cycle 16 homolog\|cell division cycle protein 16 homolog\|cyclosome subunit 6
Position	13q34
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1091T>C; p.M364T; 13:114250668-114250668	central_nervous_system; brain	glioma	Substitution - Missense
c.1685C>T; p.P562L; 13:114272265-114272265	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.467C>T; p.A156V; 13:114242206-114242206	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1019A>G; p.Y340C; 13:114250596-114250596	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.485A>G; p.Y162C; 13:114242224-114242224	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.135G>A; p.Q45Q; 13:114236830-114236830	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.135G>A; p.Q45Q; 13:114236830-114236830	thyroid	other; neoplasm	Substitution - coding silent
c.859C>G; p.L287V; 13:114246011-114246011	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1174A>C; p.S392R; 13:114257154-114257154	liver	carcinoma	Substitution - Missense
c.667T>C; p.S223P; 13:114243889-114243889	stomach	carcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	Substitution - Missense
c.618G>A; p.E206E; 13:114243333-114243333	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.553C>A; p.L185I; 13:114243268-114243268	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1665delA; p.N557fs*14; 13:114272245-114272245	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1242G>T; p.Q414H; 13:114257222-114257222	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1665delA; p.N557fs*14; 13:114272245-114272245	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1849G>T; p.D617Y; 13:114272429-114272429	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1807G>A; p.E603K; 13:114272387-114272387	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1638C>T; p.D546D; 13:114272218-114272218	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1828A>C; p.M610L; 13:114272408-114272408	breast	carcinoma	Substitution - Missense
c.187C>T; p.R63*; 13:114236882-114236882	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Nonsense
c.1682C>G; p.P561R; 13:114272262-114272262	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.106G>A; p.E36K; 13:114236801-114236801	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.721C>A; p.H241N; 13:114243943-114243943	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.106G>A; p.E36K; 13:114236801-114236801	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1784C>T; p.S595F; 13:114272364-114272364	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1528C>T; p.R510*; 13:114265165-114265165	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.641A>C; p.K214T; 13:114243863-114243863	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.79G>C; p.D27H; 13:114236675-114236675	breast	carcinoma	Substitution - Missense
c.1295T>G; p.I432S; 13:114259379-114259379	skin; mucosal	malignant_melanoma	Substitution - Missense
c.163A>G; p.R55G; 13:114236858-114236858	skin	malignant_melanoma	Substitution - Missense
c.1861T>A; p.*621R; 13:114272441-114272441	prostate	adenoma	Nonstop extension
c.1051G>A; p.D351N; 13:114250628-114250628	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1224C>T; p.V408V; 13:114257204-114257204	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1196C>T; p.P399L; 13:114257176-114257176	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.902C>A; p.S301Y; 13:114246935-114246935	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.902C>A; p.S301Y; 13:114246935-114246935	large_intestine; colon	carcinoma	Substitution - Missense
c.6C>G; p.N2K; 13:114235090-114235090	soft_tissue; blood_vessel	angiosarcoma	Substitution - Missense
c.1412C>T; p.A471V; 13:114262914-114262914	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.223C>T; p.L75F; 13:114239011-114239011	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1387G>T; p.E463*; 13:114262889-114262889	liver	carcinoma	Substitution - Nonsense
c.1387G>T; p.E463*; 13:114262889-114262889	liver	carcinoma	Substitution - Nonsense
c.1033G>T; p.A345S; 13:114250610-114250610	breast	carcinoma	Substitution - Missense
c.506T>C; p.L169P; 13:114242245-114242245	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1364G>A; p.C455Y; 13:114261936-114261936	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1364G>A; p.C455Y; 13:114261936-114261936	large_intestine; colon	carcinoma	Substitution - Missense
c.300T>G; p.N100K; 13:114239409-114239409	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1250+1G>A; p.?; 13:114257231-114257231	large_intestine; rectum	carcinoma; adenocarcinoma	Unknown
c.1034C>T; p.A345V; 13:114250611-114250611	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.779A>G; p.K260R; 13:114244901-114244901	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.169G>A; p.A57T; 13:114236864-114236864	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1493C>T; p.A498V; 13:114262995-114262995	stomach	carcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	Substitution - Missense
c.1434C>T; p.N478N; 13:114262936-114262936	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1254G>A; p.W418*; 13:114259338-114259338	skin; trunk	malignant_melanoma	Substitution - Nonsense
c.1742C>T; p.T581M; 13:114272322-114272322	prostate	carcinoma	Substitution - Missense
c.1589C>T; p.S530F; 13:114265226-114265226	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1849G>C; p.D617H; 13:114272429-114272429	urinary_tract; bladder	carcinoma	Substitution - Missense
c.937G>A; p.G313S; 13:114246970-114246970	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1554G>C; p.M518I; 13:114265191-114265191	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.501C>T; p.F167F; 13:114242240-114242240	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1374_1376+1delTAAG; p.?; 13:114261946-114261949	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.1821T>C; p.S607S; 13:114272401-114272401	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.407G>A; p.R136H; 13:114242146-114242146	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.54G>A; p.Q18Q; 13:114236650-114236650	pancreas	carcinoma	Substitution - coding silent
c.351T>C; p.P117P; 13:114239460-114239460	thyroid	other; neoplasm	Substitution - coding silent
c.351T>C; p.P117P; 13:114239460-114239460	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.605G>A; p.R202H; 13:114243320-114243320	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.318A>C; p.K106N; 13:114239427-114239427	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.604C>T; p.R202C; 13:114243319-114243319	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1058C>T; p.A353V; 13:114250635-114250635	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.330C>T; p.D110D; 13:114239439-114239439	thyroid	other; neoplasm	Substitution - coding silent
c.330C>T; p.D110D; 13:114239439-114239439	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.321C>A; p.Y107*; 13:114239430-114239430	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1602T>C; p.I534I; 13:114265239-114265239	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1845G>T; p.M615I; 13:114272425-114272425	haematopoietic_and_lymphoid_tissue; abdomen	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1512+2T>C; p.?; 13:114263016-114263016	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.261G>T; p.Q87H; 13:114239370-114239370	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.305G>T; p.R102I; 13:114239414-114239414	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1637A>G; p.D546G; 13:114272217-114272217	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1240C>G; p.Q414E; 13:114257220-114257220	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.217C>T; p.R73C; 13:114239005-114239005	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1761G>T; p.R587S; 13:114272341-114272341	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1657A>G; p.K553E; 13:114272237-114272237	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.783T>C; p.D261D; 13:114244905-114244905	pancreas	carcinoma	Substitution - coding silent
c.1569C>T; p.I523I; 13:114265206-114265206	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.958A>G; p.R320G; 13:114246991-114246991	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.567C>T; p.P189P; 13:114243282-114243282	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.958A>G; p.R320G; 13:114246991-114246991	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1226G>T; p.G409V; 13:114257206-114257206	skin	malignant_melanoma	Substitution - Missense
c.442C>A; p.L148M; 13:114242181-114242181	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1276C>A; p.L426I; 13:114259360-114259360	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1739T>G; p.L580R; 13:114272319-114272319	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1570G>A; p.E524K; 13:114265207-114265207	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.539A>G; p.E180G; 13:114242278-114242278	ovary	carcinoma	Substitution - Missense
c.1570G>A; p.E524K; 13:114265207-114265207	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.437G>A; p.R146Q; 13:114242176-114242176	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1258A>G; p.T420A; 13:114259342-114259342	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.253G>T; p.E85*; 13:114239362-114239362	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.1710A>G; p.V570V; 13:114272290-114272290	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.52C>T; p.Q18*; 13:114236648-114236648	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.913G>A; p.V305M; 13:114246946-114246946	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]