Entrez Gene

Basic Information
Gene ID	8493
Name	PPM1D
Synonymous	protein phosphatase, Mg2+/Mn2+ dependent, 1D;PPM1D;protein phosphatase, Mg2+/Mn2+ dependent, 1D
Definition	protein phosphatase 1D\|protein phosphatase 1D magnesium-dependent, delta isoform\|protein phosphatase 2C delta isoform\|protein phosphatase Wip1\|wild-type p53-induced phosphatase 1
Position	17q23.2
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
p38(h) + Wip1(h) <==> p38(h):Wip1(h) (binding)
Wip1(h) + Chk1(h) <==> Wip1(h):Chk1(h) (binding)
ATM(h) + Wip1(h) <==> ATM(h):Wip1(h) (binding)
Wip1(h) --/ TNF(h) (transrepression)
Wip1(h) --/ IL8(h) (transrepression)
Wip1(h) --/ IL6(h) (transrepression)
Wip1(h) --> RelA-p65(h){pS536} (decrease of phosphorylation)
PPM1D(h) --> Wip1(h) (expression).
RelA-p65(h) --> Wip1(h) (increase of abundance)
p38(m){p} --Wip1(h)--> p38(m) + p (dephosphorylation)
Chk1(h){pS345} --Wip1(h)--> p + Chk1(h) (dephosphorylation)
PPM1D(h) --> Wip1(h) (expression).
ATM(h){pS1981} --Wip1(h)--> ATM(h) + p (dephosphorylation)

Post Transcriptional Modification [Top]
	There is no record for PPM1D

Transcription Factors [Top]