| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 8493 |
Name | PPM1D |
Synonym | PP2C-DELTA|WIP1;protein phosphatase, Mg2+/Mn2+ dependent, 1D;PPM1D;protein phosphatase, Mg2+/Mn2+ dependent, 1D |
Definition | protein phosphatase 1D|protein phosphatase 1D magnesium-dependent, delta isoform|protein phosphatase 2C delta isoform|protein phosphatase Wip1|wild-type p53-induced phosphatase 1 |
Position | 17q23.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | p53 pathway;PANTHER;P00059 |
Pathway | p53 pathway;PID Curated;200175 |
Pathway | p53 pathway feedback loops 2;PANTHER;P04398 |
Pathway | p53 signaling pathway;KEGG PATHWAY;hsa04115 |
Disease | Breast cancer;OMIM |
External Links | |
Links to Entrez Gene | 8493 |
Links to all GeneRIF Items | 8493 |
Links to iHOP | 8493 |
Sequence Information | |
Nucleotide Sequence | >8493 : length: 4790 GGGGAAGCGCAGTGCGCAGGCGCAACTGCCTGGCTCTGCTCGCTCCGGCGCTCCGGCCCA GCTCTCGCGGACAAGTCCAGACATCGCGCGCCCCCCCTTCTCCGGGTCCGCCCCCTCCCC CTTCTCGGCGTCGTCGAAGATAAACAATAGTTGGCCGGCGAGCGCCTAGTGTGTCTCCCG CCGCCGGATTCGGCGGGCTGCGTGGGACCGGCGGGATCCCGGCCAGCCGGCCATGGCGGG GCTGTACTCGCTGGGAGTGAGCGTCTTCTCCGACCAGGGCGGGAGGAAGTACATGGAGGA CGTTACTCAAATCGTTGTGGAGCCCGAACCGACGGCTGAAGAAAAGCCCTCGCCGCGGCG GTCGCTGTCTCAGCCGTTGCCTCCGCGGCCGTCGCCGGCCGCCCTTCCCGGCGGCGAAGT CTCGGGGAAAGGCCCAGCGGTGGCAGCCCGAGAGGCTCGCGACCCTCTCCCGGACGCCGG GGCCTCGCCGGCACCTAGCCGCTGCTGCCGCCGCCGTTCCTCCGTGGCCTTTTTCGCCGT GTGCGACGGGCACGGCGGGCGGGAGGCGGCACAGTTTGCCCGGGAGCACTTGTGGGGTTT CATCAAGAAGCAGAAGGGTTTCACCTCGTCCGAGCCGGCTAAGGTTTGCGCTGCCATCCG CAAAGGCTTTCTCGCTTGTCACCTTGCCATGTGGAAGAAACTGGCGGAATGGCCAAAGAC TATGACGGGTCTTCCTAGCACATCAGGGACAACTGCCAGTGTGGTCATCATTCGGGGCAT GAAGATGTATGTAGCTCACGTAGGTGACTCAGGGGTGGTTCTTGGAATTCAGGATGACCC GAAGGATGACTTTGTCAGAGCTGTGGAGGTGACACAGGACCATAAGCCAGAACTTCCCAA GGAAAGAGAACGAATCGAAGGACTTGGTGGGAGTGTAATGAACAAGTCTGGGGTGAATCG TGTAGTTTGGAAACGACCTCGACTCACTCACAATGGACCTGTTAGAAGGAGCACAGTTAT TGACCAGATTCCTTTTCTGGCAGTAGCAAGAGCACTTGGTGATTTGTGGAGCTATGATTT CTTCAGTGGTGAATTTGTGGTGTCACCTGAACCAGACACAAGTGTCCACACTCTTGACCC TCAGAAGCACAAGTATATTATATTGGGGAGTGATGGACTTTGGAATATGATTCCACCACA AGATGCCATCTCAATGTGCCAGGACCAAGAGGAGAAAAAATACCTGATGGGTGAGCATGG ACAATCTTGTGCCAAAATGCTTGTGAATCGAGCATTGGGCCGCTGGAGGCAGCGTATGCT CCGAGCAGATAACACTAGTGCCATAGTAATCTGCATCTCTCCAGAAGTGGACAATCAGGG AAACTTTACCAATGAAGATGAGTTATACCTGAACCTGACTGACAGCCCTTCCTATAATAG TCAAGAAACCTGTGTGATGACTCCTTCCCCATGTTCTACACCACCAGTCAAGTCACTGGA GGAGGATCCATGGCCAAGGGTGAATTCTAAGGACCATATACCTGCCCTGGTTCGTAGCAA TGCCTTCTCAGAGAATTTTTTAGAGGTTTCAGCTGAGATAGCTCGAGAGAATGTCCAAGG TGTAGTCATACCCTCAAAAGATCCAGAACCACTTGAAGAAAATTGCGCTAAAGCCCTGAC TTTAAGGATACATGATTCTTTGAATAATAGCCTTCCAATTGGCCTTGTGCCTACTAATTC AACAAACACTGTCATGGACCAAAAAAATTTGAAGATGTCAACTCCTGGCCAAATGAAAGC CCAAGAAATTGAAAGAACCCCTCCAACAAACTTTAAAAGGACATTAGAAGAGTCCAATTC TGGCCCCCTGATGAAGAAGCATAGACGAAATGGCTTAAGTCGAAGTAGTGGTGCTCAGCC TGCAAGTCTCCCCACAACCTCACAGCGAAAGAACTCTGTTAAACTCACCATGCGACGCAG ACTTAGGGGCCAGAAGAAAATTGGAAATCCTTTACTTCATCAACACAGGAAAACTGTTTG TGTTTGCTGAAATGCATCTGGGAAATGAGGTTTTTCCAAACTTAGGATATAAGAGGGCTT TTTAAATTTGGTGCCGATGTTGAACTTTTTTTAAGGGGAGAAAATTAAAAGAAATATACA GTTTGACTTTTTGGAATTCAGCAGTTTTATCCTGGCCTTGTACTTGCTTGTATTGTAAAT GTGGATTTTGTAGATGTTAGGGTATAAGTTGCTGTAAAATTTGTGTAAATTTGTATCCAC ACAAATTCAGTCTCTGAATACACAGTATTCAGAGTCTCTGATACACAGTAATTGTGACAA TAGGGCTAAATGTTTAAAGAAATCAAAAGAATCTATTAGATTTTAGAAAAACATTTAAAC TTTTTAAAATACTTATTAAAAAATTTGTATAAGCCACTTGTCTTGAAAACTGTGCAACTT TTTAAAGTAAATTATTAAGCAGACTGGAAAAGTGATGTATTTTCATAGTGACCTGTGTTT CACTTAATGTTTCTTAGAGCCAAGTGTCTTTTAAACATTATTTTTTATTTCTGATTTCAT AATTCAGAACTAAATTTTTCATAGAAGTGTTGAGCCATGCTACAGTTAGTCTTGTCCCAA TTAAAATACTATGCAGTATCTCTTACATCAGTAGCATTTTTCTAAAACCTTAGTCATCAG ATATGCTTACTAAATCTTCAGCATAGAAGGAAGTGTGTTTGCCTAAAACAATCTAAAACA ATTCCCTTCTTTTTCATCCCAGACCAATGGCATTATTAGGTCTTAAAGTAGTTACTCCCT TCTCGTGTTTGCTTAAAATATGTGAAGTTTTCCTTGCTATTTCAATAACAGATGGTGCTG CTAATTCCCAACATTTCTTAAATTATTTTATATCATACAGTTTTCATTGATTATATGGGT ATATATTCATCTAATAAATCAGTGAACTGTTCCTCATGTTGCTGAATTTGTAGTTGTTGG TTTATTTTAATGGTATGTACAAGTTGAGTATCCCTTATCCAAAATGCTTGGGACCAGAAG TGTTTCAGATTTTTTAAAATTTTGGAATATTTGCTTTATACTGAGCTTTTGAGTGTTCCC AATCTGAAATTCAAAATGCTCTAATGAGCATTTCCTTTGAGCATCATGCCTGCTCTGAAA AAGTTTCTGATTCTGGAGCATTTTGGATTTTGGATTTTCAGATTAGGGATGCTTAACCTG GATTAACATTCTGTTGTGCCATGATCATGCTTTACAGTGAGTGTATTTTATTTATTTATT ATTTTGTTTGTTTGTTTGAGATGGAGTCTCACTCTGTCATCCAGGCTAGAGTGCAGTGGC GTGATCTCGGCTGACTGCAACCTCTGCCTCCCGGGTTCAAGTGATTCTCCTGCCTCAATC TCTCTCCCCAGAAGCTGGGATTACAGGTGTGTGCCACCACACCCGGCTAATTTTTTTTTT TTTTTTTGAGATGGAGTCTAGCTCTGTCATCCAGGCTGGAGTGCAGTGGTGTGATCTCGG CTCCCTGCAACCTCTGCCTTCTGGGTTCCTGCGATTCTCCTGCCTCAGCCTCCTGAGTAG CTGAGATTACAGGCACGCGCCACTGTGCCCAGCCAATTTTTGTATTTTTAGTAGAGATGG GGTTTCACATGTCAGTCATGCTGGTCTTGATCTCCTGACCTCGTGATCCACCCGCCTCGA CCTCCCAAAGTACTGGGATTACAGGCGTGAGCCACCGCATCCGGCCTGAGTTTTATGCTT TCAATGTATTTCTTACATTTCAGTTCAAGTGATTTTCATGTCTCAGCCTCCTGAGTAGCT GGAACTACAGGTGCGTGCCACCATGCCTGGCTAAGTTTTGTATTTTTAGTAGAGATGGGT TTTCATCATGTTGGCCAAGATGGTCTTGATCTCTTGACCTCATGATCCACCAGCCTAGGC CTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGTGCCCAGCCAACTATGCCATTATT TAACCATGTCCACACATTCTGGTTATTTTCAATATTTTGCAGAAGATAATTCTTGATCGG TGTGTCTTATGCCACAAGGATTAAAATATGTATTCATTGCTACAAAACAATATCTCGAAA TTTAGCAGTTTAAAACAACAAATATTATCTCCAGTTTCTGAGCCTCAGAAATCTGAGAGT GGTTTAGCTGGGTGATAGTCTCGTGGTTTTGGTCAAGCTACCAACCAGGGCTACAATCTT TCGAAGGTGTCATTGGGGCTAGAAGATCTGCTTCCCGCAAGACTCACAGCTGTTGGCAGG AGACCTCAGTTTGTTGCCACATGTTCCCCTCCAGAGGGCCTCTCACAACATGGCAGTTAT TTGTCCCCAGAGCAAGCAACACCGGAGGGCAAGGAAGAAGCCATGATGTTTTTTGTAACC TAGCCTCTGAAAGTGTCATACCAATTCTGTATTTTGTTGGTCACACAGACCAAGTCAACT ACAACGTGGGAGACTCCTACACAAGGCATGAATTCTAGGAGGTGGGCATTTTTAAGTGTC ATCTGGAAGGAGGCTGTCACAACCTGGAAGTTAAAAGCATTGATATTCTGAAATACAGCG TGTATAACATTGTTTTAGTAGGGTGTGCAATAGTTATGTTTTGGTAATAGCATTAATGAA CAATGTTATTTTCATCTTCCAGACATCTGGAAGATTGCTCTAGTGGAGTAAAACATCTTA ATGTATTTTGTCCCTAAATAAACTATCTCACTAACAAAAAAAAAAAAAAA |
Protein Sequence | >8493 : length: 605 MAGLYSLGVSVFSDQGGRKYMEDVTQIVVEPEPTAEEKPSPRRSLSQPLPPRPSPAALPG GEVSGKGPAVAAREARDPLPDAGASPAPSRCCRRRSSVAFFAVCDGHGGREAAQFAREHL WGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLAEWPKTMTGLPSTSGTTASVVII RGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEGLGGSVMNKSG VNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDLWSYDFFSGEFVVSPEPDTSVHT LDPQKHKYIILGSDGLWNMIPPQDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQ RMLRADNTSAIVICISPEVDNQGNFTNEDELYLNLTDSPSYNSQETCVMTPSPCSTPPVK SLEEDPWPRVNSKDHIPALVRSNAFSENFLEVSAEIARENVQGVVIPSKDPEPLEENCAK ALTLRIHDSLNNSLPIGLVPTNSTNTVMDQKNLKMSTPGQMKAQEIERTPPTNFKRTLEE SNSGPLMKKHRRNGLSRSSGAQPASLPTTSQRKNSVKLTMRRRLRGQKKIGNPLLHQHRK TVCVC |