Entrez Gene

Basic Information
Gene ID	7042
Name	TGFB2
Synonymous	transforming growth factor, beta 2;TGFB2;transforming growth factor, beta 2
Definition	BSC-1 cell growth inhibitor\|G-TSF\|cetermin\|glioblastoma-derived T-cell suppressor factor\|polyergin\|prepro-transforming growth factor beta-2\|transforming growth factor beta-2
Position	1q41
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
heparin + TGFbeta2(h) <==> heparin:TGFbeta2(h) (binding)
HSPGs(r) + TGFbeta2(h) <==> HSPGs(r):TGFbeta2(h) (binding)
TGFbeta2(h) + TGFbetaR-III(r) + TGFbetaR-II(h) <==> TGFbeta2(h):TGFbetaR-III(r):TGFbetaR-II(h) (binding)
TGFbeta2(h) + TGFbetaR-III(h) <==> TGFbeta2(h):TGFbetaR-III(h) (binding)
TGFbeta2(h) --> fibronectin(h) (increase of abundance)
TGFbeta2(h) --> PAI1(h) (increase of abundance)
TGFbeta2(h) --> Smad2(h){p} (increase of phosphorylation)
TGFbeta2(h) --> p15INK4b(r) (increase of abundance)
TGFbeta2(h) --/ Cdk2(r) (decrease of abundance)
TGFbeta2(h) --> pRb(r){p} (decrease of phosphorylation)
TGFbeta2(h) --> IL-11(h) (increase of secretion)
TGFbeta2(h) --> IL11(h) (transactivation)
TGFB2(h) --> TGFbeta2(h) (expression).
IL-1beta(h) --> TGFbeta2(h) (increase of secretion)
TNF-alpha(h) --> TGFbeta2(h) (increase of secretion)
IFNgamma(h) --> TGFbeta2(h) (decrease of secretion)
TGFB2(h) --> TGFbeta-2A(h) (expression).
TGFB2(h) --> TGFbeta-2B(h) (expression).
TGFB2(h) --> TGFB2(h) (expression).
hsa-miR-141 --/ TGFB2(h) (translational repression).

Location (AA)	PTM type	Database
Post Transcriptional Modification [Top]
72	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
140	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
241	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0

Chromosome	Location	Source
Methylation Profile [Top]
chr1	Promoter: 216584991 - 216586991	Agilent_014791
chr1	Promoter: 216584991 - 216586991	GoldenGate_Methylation_Cancer_Panel_I
chr1	Promoter: 216584991 - 216586991	GSE27584
chr1	Promoter: 216584991 - 216586991	Agilent_014791_44K

Transcription Factors [Top]