Entrez Gene

Basic Information
Gene ID	64750
Name	SMURF2
Synonymous	SMAD specific E3 ubiquitin protein ligase 2;SMURF2;SMAD specific E3 ubiquitin protein ligase 2
Definition	E3 ubiquitin ligase SMURF2\|E3 ubiquitin-protein ligase SMURF2\|SMAD ubiquitination regulatory factor 2\|SMAD-specific E3 ubiquitin-protein ligase 2\|hSMURF2
Position	17q22-q23
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
Smad1(h) + Smurf-2(h) <==> Smad1(h):Smurf-2(h) (binding)
Smad2-L(h) + Smurf-2(h) <==> Smad2-L(h):Smurf-2(h) (binding)
Smad3(h) + Smurf-2(h) <==> Smad3(h):Smurf-2(h) (binding)
Smad7(h) + Smurf-2(h) <==> Smad7(h):Smurf-2(h) (binding)
TGFbeta1(h):TGFbetaR-II(h):TGFbetaR-I(h) + Smad7(h) + Smurf-2(h) <==> TGFbeta1(h):TGFbetaR-II(h):TGFbetaR-I(h):Smad7(h):Smurf-2(h) (binding)
Smurf-2(h) + Smad7(m.s.) <==> Smad7(m.s.):Smurf-2(h) (binding)
beta-catenin(h) + Smurf-2(h) <==> beta-catenin(h):Smurf-2(h) (binding)
SMURF2(h) --> Smurf-2(h) (expression).
Smad1(h) + n ubiquitin(h) --Smurf-2(h)--> Smad1(h){ub(n)} (ubiquitination)
Smad2-L(h) + n ubiquitin(h) --Smurf-2(h)--> Smad2-L(h){ub(n)} (ubiquitination)
SMURF2(h) --> Smurf-2(h) (expression).

Post Transcriptional Modification [Top]
	There is no record for SMURF2

Transcription Factors [Top]