| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 64750 |
Name | SMURF2 |
Synonymous | SMAD specific E3 ubiquitin protein ligase 2;SMURF2;SMAD specific E3 ubiquitin protein ligase 2 |
Definition | E3 ubiquitin ligase SMURF2|E3 ubiquitin-protein ligase SMURF2|SMAD ubiquitination regulatory factor 2|SMAD-specific E3 ubiquitin-protein ligase 2|hSMURF2 |
Position | 17q22-q23 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
SMAD1 | NCI_NATURE; |
in same component |
SMAD2 | NCI_NATURE; |
in same component |
SMAD7 | CELL_MAP; |
interacts with |
ACBD3 | HPRD; |
interacts with |
ACBD3 | MINT; |
interacts with |
ACOX3 | HPRD; |
interacts with |
ACOX3 | MINT; |
interacts with |
ACTA1 | MINT; |
interacts with |
AIMP1 | BIOGRID; |
interacts with |
Anapc5 | BIOGRID; |
interacts with |
ANAPC5 | HPRD; |
interacts with |
ARHGAP5 | HPRD; |
interacts with |
ARHGAP5 | MINT; |
interacts with |
Arhgef1 | BIOGRID; |
interacts with |
Ash2l | BIOGRID; |
interacts with |
ASH2L | HPRD; |
interacts with |
ATP5B | MINT; |
interacts with |
CANX | HPRD; |
interacts with |
CANX | MINT; |
interacts with |
CCAR1 | MINT; |
interacts with |
CUEDC1 | HPRD; |
interacts with |
CUEDC1 | MINT; |
interacts with |
DAB2 | HPRD; |
interacts with |
DAB2 | MINT; |
interacts with |
DAZAP2 | MINT; |
interacts with |
DCAF6 | MINT; |
interacts with |
DES | MINT; |
interacts with |
DGCR2 | HPRD; |
interacts with |
DGCR2 | MINT; |
interacts with |
DVL2 | HPRD; |
interacts with |
ECHS1 | MINT; |
interacts with |
EEF1G | MINT; |
interacts with |
EIF3E | MINT; |
interacts with |
Epha1 | BIOGRID; |
interacts with |
FAM175B | HPRD; |
interacts with |
FAM175B | MINT; |
interacts with |
FHL2 | MINT; |
interacts with |
Fkbp4 | BIOGRID; |
interacts with |
FKBP4 | HPRD; |
interacts with |
FLNB | HPRD; |
interacts with |
FLNB | MINT; |
interacts with |
FLNC | MINT; |
interacts with |
Gar1 | BIOGRID; |
interacts with |
GFM1 | MINT; |
interacts with |
GMEB1 | MINT; |
interacts with |
Gng2 | BIOGRID; |
interacts with |
GNG2 | HPRD; |
interacts with |
GSK3B | BIOGRID; |
interacts with |
Hdgfrp3 | BIOGRID; |
interacts with |
HDGFRP3 | HPRD; |
interacts with |
Ing2 | BIOGRID; |
interacts with |
ING2 | HPRD; |
interacts with |
Ing2 | MINT; |
interacts with |
Irf3 | BIOGRID; |
interacts with |
IRF3 | HPRD; |
interacts with |
Irf8 | BIOGRID; |
interacts with |
IRF8 | HPRD; |
interacts with |
LAPTM5 | HPRD; |
interacts with |
LAPTM5 | MINT; |
interacts with |
LMCD1 | MINT; |
interacts with |
MRPL19 | MINT; |
interacts with |
MRPL2 | MINT; |
interacts with |
MRPL41 | MINT; |
interacts with |
MYBPC3 | MINT; |
interacts with |
MYOZ1 | MINT; |
interacts with |
NDUFA1 | MINT; |
interacts with |
NEBL | MINT; |
interacts with |
NEB | MINT; |
interacts with |
NEDD4 | BIOGRID; |
interacts with |
Nek6 | BIOGRID; |
interacts with |
NEK6 | HPRD; |
interacts with |
Nkiras1 | BIOGRID; |
interacts with |
NKIRAS1 | HPRD; |
interacts with |
NOMO1 | MINT; |
interacts with |
NRAS | HPRD; |
interacts with |
PARD6A | HPRD; |
interacts with |
Ppid | BIOGRID; |
interacts with |
PPID | HPRD; |
interacts with |
PRICKLE1 | HPRD; |
interacts with |
PRICKLE2 | HPRD; |
interacts with |
Rab13 | BIOGRID; |
interacts with |
RAB13 | HPRD; |
interacts with |
Rab13 | MINT; |
interacts with |
Rab14 | BIOGRID; |
interacts with |
RAB14 | HPRD; |
interacts with |
Rab17 | BIOGRID; |
interacts with |
RAB17 | HPRD; |
interacts with |
Rab17 | MINT; |
interacts with |
Rab22a | BIOGRID; |
interacts with |
RAB22A | HPRD; |
interacts with |
RAB25 | HPRD; |
interacts with |
RAN | HPRD; |
interacts with |
RAP1B | HPRD; |
interacts with |
RAP1B | MINT; |
interacts with |
Rasd2 | BIOGRID; |
interacts with |
RASD2 | HPRD; |
interacts with |
RASL12 | HPRD; |
interacts with |
RHOA | BIOGRID; |
interacts with |
Rhod | BIOGRID; |
interacts with |
RHOD | HPRD; |
interacts with |
Rhod | MINT; |
interacts with |
RNF111 | HPRD; |
interacts with |
RNF111 | MINT; |
interacts with |
RNF11 | BIOGRID; |
interacts with |
RNF11 | HPRD; |
interacts with |
RNF11 | MINT; |
interacts with |
Rnf14 | BIOGRID; |
interacts with |
Rnf2 | BIOGRID; |
interacts with |
RNF2 | HPRD; |
interacts with |
Rnf2 | MINT; |
interacts with |
Rras2 | BIOGRID; |
interacts with |
RUNX3 | BIOGRID; |
interacts with |
RUNX3 | HPRD; |
interacts with |
SF3A2 | HPRD; |
interacts with |
SF3A2 | MINT; |
interacts with |
SKIL | BIOGRID; |
interacts with |
SKIL | HPRD; |
interacts with |
Smad1 | BIOGRID; |
interacts with |
SMAD1 | BIOGRID; |
interacts with |
SMAD1 | HPRD; |
interacts with |
SMAD1 | MINT; |
interacts with |
Smad2 | BIOGRID; |
interacts with |
SMAD2 | BIOGRID; |
interacts with |
SMAD2 | HPRD; |
interacts with |
SMAD2 | MINT; |
interacts with |
SMAD5 | BIOGRID; |
interacts with |
SMAD5 | HPRD; |
interacts with |
SMAD5 | MINT; |
interacts with |
Smad6 | BIOGRID; |
interacts with |
SMAD6 | BIOGRID; |
interacts with |
SMAD6 | HPRD; |
interacts with |
SMAD6 | MINT; |
interacts with |
Smad7 | BIOGRID; |
interacts with |
SMAD7 | BIOGRID; |
interacts with |
SMAD7 | CELL_MAP; |
interacts with |
SMAD7 | HPRD; |
interacts with |
SMAD7 | MINT; |
interacts with |
Smap1 | BIOGRID; |
interacts with |
SMAP1 | HPRD; |
interacts with |
SMURF1 | BIOGRID; |
interacts with |
SNRNP70 | HPRD; |
interacts with |
SNRNP70 | MINT; |
interacts with |
SOCS6 | HPRD; |
interacts with |
SPG20 | HPRD; |
interacts with |
SPG20 | MINT; |
interacts with |
SQSTM1 | MINT; |
interacts with |
SRSF4 | HPRD; |
interacts with |
STAMBP | BIOGRID; |
interacts with |
TCAP | MINT; |
interacts with |
TFPI2 | HPRD; |
interacts with |
TFPI2 | MINT; |
interacts with |
TGFBR1 | BIOGRID; |
interacts with |
TGFBR2 | BIOGRID; |
interacts with |
TMEM139 | HPRD; |
interacts with |
TMEM139 | MINT; |
interacts with |
TNFRSF1B | BIOGRID; |
interacts with |
TNFRSF1B | HPRD; |
interacts with |
TNNI2 | MINT; |
interacts with |
TNNI3 | MINT; |
interacts with |
TNNT1 | MINT; |
interacts with |
TNPO3 | HPRD; |
interacts with |
TNPO3 | MINT; |
interacts with |
TRAF2 | BIOGRID; |
interacts with |
TRAF2 | HPRD; |
interacts with |
TRAF4 | HPRD; |
interacts with |
TRAF4 | MINT; |
interacts with |
TSSK4 | HPRD; |
interacts with |
TTN | MINT; |
interacts with |
TXNIP | HPRD; |
interacts with |
TXNIP | MINT; |
interacts with |
UBE2L3 | BIOGRID; |
interacts with |
UXT | MINT; |
interacts with |
ZBTB44 | HPRD; |
Metabolic Interaction [Top] | ||
There is no record for SMURF2 | ||
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
DYNLRB1 | NCI_NATURE; |
reacts with |
SMAD1 | NCI_NATURE; |
reacts with |
SMAD2 | NCI_NATURE; |
reacts with |
SMAD7 | CELL_MAP; |
reacts with |
SMURF2 | CELL_MAP; |
reacts with |
SMURF2 | NCI_NATURE; |
reacts with |
TGFBR1 | NCI_NATURE; |
reacts with |
TGFBR2 | NCI_NATURE; |