Entrez Gene

Basic Information
Gene ID	6197
Name	RPS6KA3
Synonymous	ribosomal protein S6 kinase, 90kDa, polypeptide 3;RPS6KA3;ribosomal protein S6 kinase, 90kDa, polypeptide 3
Definition	MAP kinase-activated protein kinase 1b\|MAPK-activated protein kinase 1b\|MAPKAP kinase 1b\|MAPKAPK-1b\|RSK-2\|S6K-alpha-3\|insulin-stimulated protein kinase 1\|p90-RSK 3\|ribosomal S6 kinase 2\|ribosomal protein S6 kinase alpha-3
Position	Xp22.2-p22.1
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
ERK1(h) + RSK2(h) <==> ERK1(h):RSK2(h) (binding)
ERK2(h) + RSK2(h) <==> ERK2(h):RSK2(h) (binding)
RSK2(h) + ERK5(h) <==> RSK2(h):ERK5(h) (binding)
Rps6ka3(h) --> RSK2(h) (expression).
CREB(h) + ATP --RSK2(h)--> CREB(h){p} + ADP (phosphorylation)
p53(h) + ATP --RSK2(h)--> p53(h){pS15} + ADP (phosphorylation)
p53-isoform1(h) + RSK2(h) <==> p53-isoform1(h):RSK2(h) (binding)
Rps6ka3(h) --> RSK2(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
227	Phosphoserine.		Swiss-Prot 53.0
231	Phosphothreonine.		Swiss-Prot 53.0
365	Phosphothreonine.		Swiss-Prot 53.0
369	Phosphoserine.		Swiss-Prot 53.0
386	Phosphoserine (By similarity).		Swiss-Prot 53.0
577	Phosphothreonine (By similarity).		Swiss-Prot 53.0
715	Phosphoserine.		Swiss-Prot 53.0
737	Phosphoserine (By similarity).		Swiss-Prot 53.0
707	Phosphotyrosine (FGFR1)	12601080	Phospho.ELM 6.0
227	Phosphoserine	10980595	Phospho.ELM 6.0
365	Phosphothreonine	10980595;17081983	Phospho.ELM 6.0
369	Phosphoserine	10980595;17081983	Phospho.ELM 6.0
386	Phosphoserine	10980595	Phospho.ELM 6.0
577	Phosphothreonine (MAPK3)	10980595	Phospho.ELM 6.0

Transcription Factors [Top]