Entrez Gene

Basic Information
Gene ID	5290
Name	PIK3CA
Synonymous	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha;PIK3CA;phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
Definition	PI3-kinase p110 subunit alpha\|PI3K-alpha\|phosphatidylinositol 3-kinase, catalytic, 110-KD, alpha\|phosphatidylinositol 3-kinase, catalytic, alpha polypeptide\|phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform\|phosphatidylinosito
Position	3q26.3
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
p110alpha(h) + H-Ras(h):GTP <==> p110alpha(h):H-Ras(h):GTP (binding)
p110alpha(h) + H-Ras(m.s.) <==> p110alpha(h):H-Ras(m.s.) (binding)
p110alpha(h) --> p85alpha(h) (binding)
p110alpha(h) + ER-alpha(h) <==> p110alpha(h):ER-alpha(h) (binding)
p85(h) + p110alpha(h) + Hsp50(h) + Hsp90(h) + ezrin(h) + CD44(h) + ErbB2(h){p} <==> p85(h):p110alpha(h):Hsp50(h):Hsp90(h):ezrin(h):CD44(h):ErbB2(h){p} (binding)
p110alpha(h) + Hsp50(h) + ezrin(h) + CD44(h) + ErbB2(h){p} <==> p110alpha(h):Hsp50(h):ezrin(h):CD44(h):ErbB2(h){p} (binding)
p110alpha(h) + ATP --> p110alpha(h){pY} + ADP (phosphorylation)
Pik3ca(h) --> p110alpha(h) (expression).
G-alpha-q(m) --> p110alpha(h) (binding)
VEGF-A(m.s.) --> p110alpha(h) (increase of abundance)
Pik3ca(h) --> p110alpha(h) (expression).

Post Transcriptional Modification [Top]
	There is no record for PIK3CA

Transcription Factors [Top]