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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

5290

Name

PIK3CA

Synonymous

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha;PIK3CA;phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

Definition

PI3-kinase p110 subunit alpha|PI3K-alpha|phosphatidylinositol 3-kinase, catalytic, 110-KD, alpha|phosphatidylinositol 3-kinase, catalytic, alpha polypeptide|phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform|phosphatidylinosito

Position

3q26.3

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 AGAP2NCI_NATURE;

in same component

 ARNCI_NATURE;

in same component

 CD19NCI_NATURE;

in same component

 CD28REACTOME;

in same component

 CSF2NCI_NATURE;

in same component

 CSF2RANCI_NATURE;

in same component

 CSF2RBNCI_NATURE;

in same component

 DAB1NCI_NATURE;

in same component

 EFNA1NCI_NATURE;

in same component

 EGFREACTOME;

in same component

 EGFRREACTOME;

in same component

 EPHA2NCI_NATURE;

in same component

 ERBB2IMID;

in same component

 ESR1NCI_NATURE;

in same component

 FRS2REACTOME;

in same component

 FYNNCI_NATURE;

in same component

 GAB1IMID;

in same component

 GAB1NCI_NATURE;

in same component

 GAB1REACTOME;

in same component

 GAB2NCI_NATURE;

in same component

 GAB2REACTOME;

in same component

 Gnb2IMID;

in same component

 GNG2NCI_NATURE;

in same component

 GRB10IMID;

in same component

 GSNNCI_NATURE;

in same component

 IL1BNCI_NATURE;

in same component

 IL1R1NCI_NATURE;

in same component

 IL2NCI_NATURE;

in same component

 IL2RANCI_NATURE;

in same component

 IL2RBNCI_NATURE;

in same component

 IL2RGNCI_NATURE;

in same component

 IL3NCI_NATURE;

in same component

 IL3RANCI_NATURE;

in same component

 IRS1IMID;

in same component

 IRS2IMID;

in same component

 ITGA6NCI_NATURE;

in same component

 JAK1NCI_NATURE;

in same component

 JAK2NCI_NATURE;

in same component

 JAK3NCI_NATURE;

in same component

 KITREACTOME;

in same component

 LCKNCI_NATURE;

in same component

 NRASIMID;

in same component

 PELP1NCI_NATURE;

in same component

 PIK3CBCELL_MAP;

in same component

 PIK3CGCELL_MAP;

in same component

 PIK3R1NCI_NATURE;

in same component

 PIK3R1REACTOME;

in same component

 PIK3R2CELL_MAP;

in same component

 PIK3R3CELL_MAP;

in same component

 PTPN11IMID;

in same component

 PTPN11NCI_NATURE;

in same component

 PTPN11REACTOME;

in same component

 RELNNCI_NATURE;

in same component

 SHC1IMID;

in same component

 SHC1NCI_NATURE;

in same component

 SOS1NCI_NATURE;

in same component

 SRCNCI_NATURE;

in same component

 TUBA1AIMID;

in same component

 VLDLRNCI_NATURE;

in same component

 YWHAZNCI_NATURE;

interacts with

 ADAP1BIOGRID;

interacts with

 APLP2HPRD;

interacts with

 APPL1HPRD;

interacts with

 ARHGAP20INTACT;

interacts with

 ARHGEF1BIOGRID;

interacts with

 ASAP1INTACT;

interacts with

 ASAP2INTACT;

interacts with

 ATRBIOGRID;

interacts with

 C11orf84INTACT;

interacts with

 CBLBINTACT;

interacts with

 CBLBIOGRID;

interacts with

 CBLINTACT;

interacts with

 CD2APINTACT;

interacts with

 CSKINTACT;

interacts with

 CSRP1INTACT;

interacts with

 DGKZBIOGRID;

interacts with

 DIAPH1INTACT;

interacts with

 DNM1INTACT;

interacts with

 DOCK4INTACT;

interacts with

 DOCK5INTACT;

interacts with

 EGFRINTACT;

interacts with

 ELMO2INTACT;

interacts with

 EPS15L1INTACT;

interacts with

 ERRFI1INTACT;

interacts with

 FAM59AINTACT;

interacts with

 FAM59BINTACT;

interacts with

 FGD6INTACT;

interacts with

 FRS2INTACT;

interacts with

 GAB1CELL_MAP;

interacts with

 GAB2INTACT;

interacts with

 GABRB1HPRD;

interacts with

 GIT1INTACT;

interacts with

 GNAQBIOGRID;

interacts with

 GNAQHPRD;

interacts with

 GRIN2BHPRD;

interacts with

 GSNBIOGRID;

interacts with

 HDGFRP3INTACT;

interacts with

 HGSINTACT;

interacts with

 HRASBIOGRID;

interacts with

 HRASHPRD;

interacts with

 HUNKINTACT;

interacts with

 IGF2BP1INTACT;

interacts with

 IL3HPRD;

interacts with

 INPPL1INTACT;

interacts with

 IRS1BIOGRID;

interacts with

 IRS1INTACT;

interacts with

 IRS1MINT;

interacts with

 IRS2HPRD;

interacts with

 IRS2INTACT;

interacts with

 IRS4BIOGRID;

interacts with

 IRS4HPRD;

interacts with

 IRS4INTACT;

interacts with

 ITGB4CELL_MAP;

interacts with

 KHDRBS1INTACT;

interacts with

 KRASBIOGRID;

interacts with

 LCKBIOGRID;

interacts with

 LCKHPRD;

interacts with

 LYNNCI_NATURE;

interacts with

 MAP4K5INTACT;

interacts with

 MRASHPRD;

interacts with

 MYCBPINTACT;

interacts with

 NCKAP1INTACT;

interacts with

 NISCHINTACT;

interacts with

 NOTCH1BIOGRID;

interacts with

 NRASHPRD;

interacts with

 ODR4INTACT;

interacts with

 PDGFRBHPRD;

interacts with

 PEAK1INTACT;

interacts with

 PIK3AP1INTACT;

interacts with

 PIK3C2BINTACT;

interacts with

 PIK3CBINTACT;

interacts with

 PIK3R1BIOGRID;

interacts with

 PIK3R1HPRD;

interacts with

 PIK3R1INTACT;

interacts with

 Pik3r1MINT;

interacts with

 PIK3R1MINT;

interacts with

 PIK3R2INTACT;

interacts with

 PIK3R3BIOGRID;

interacts with

 PIK3R3HPRD;

interacts with

 PIK3R3INTACT;

interacts with

 PPM1BINTACT;

interacts with

 PPP1CAINTACT;

interacts with

 PPP5CINTACT;

interacts with

 PRKCDHPRD;

interacts with

 PSTPIP2INTACT;

interacts with

 PTPLAD1INTACT;

interacts with

 PTPN11INTACT;

interacts with

 PTPN12INTACT;

interacts with

 RADILINTACT;

interacts with

 RASD2BIOGRID;

interacts with

 RASD2HPRD;

interacts with

 RASGRP3BIOGRID;

interacts with

 RPS6KB1HPRD;

interacts with

 SGK1BIOGRID;

interacts with

 SH2D5INTACT;

interacts with

 SH3KBP1HPRD;

interacts with

 SH3PXD2AINTACT;

interacts with

 SH3PXD2BINTACT;

interacts with

 SHC1INTACT;

interacts with

 SIRPAINTACT;

interacts with

 SLAIN2INTACT;

interacts with

 SLC25A13INTACT;

interacts with

 SLC25A5INTACT;

interacts with

 SLC25A6INTACT;

interacts with

 SLC9A3R1BIOGRID;

interacts with

 SLC9A3R2BIOGRID;

interacts with

 SOS1INTACT;

interacts with

 SOS2INTACT;

interacts with

 STAMBPINTACT;

interacts with

 SYNJ1INTACT;

interacts with

 TECINTACT;

interacts with

 TICAM1HPRD;

interacts with

 TSG101INTACT;

interacts with

 TTYH2INTACT;

interacts with

 UBTFBIOGRID;

interacts with

 VAV3INTACT;

interacts with

 WASLINTACT;

interacts with

 WDR44INTACT;

interacts with

 WDR6INTACT;

interacts with

 WDR77INTACT;

interacts with

 WIPF1INTACT;

interacts with

 WIPF2INTACT;

interacts with

 WIPF3INTACT;

interacts with

 YWHABINTACT;

interacts with

 YWHAEINTACT;

interacts with

 YWHAGINTACT;

interacts with

 YWHAHBIOGRID;

interacts with

 YWHAHINTACT;

interacts with

 YWHAQINTACT;

interacts with

 YWHAZINTACT;

Metabolic Interaction   [Top]

There is no record for PIK3CA

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 AGAP2NCI_NATURE;

reacts with

 ARNCI_NATURE;

reacts with

 CD19NCI_NATURE;

reacts with

 CD28REACTOME;

reacts with

 CDH1NCI_NATURE;

reacts with

 CSF2NCI_NATURE;

reacts with

 CSF2RANCI_NATURE;

reacts with

 CSF2RBNCI_NATURE;

reacts with

 DAB1NCI_NATURE;

reacts with

 EFNA1NCI_NATURE;

reacts with

 EGFREACTOME;

reacts with

 EGFRREACTOME;

reacts with

 EPB41L1NCI_NATURE;

reacts with

 EPHA2NCI_NATURE;

reacts with

 ERBB2IMID;

reacts with

 ESR1NCI_NATURE;

reacts with

 FRS2REACTOME;

reacts with

 FYNNCI_NATURE;

reacts with

 GAB1IMID;

reacts with

 GAB1NCI_NATURE;

reacts with

 GAB1REACTOME;

reacts with

 GAB2NCI_NATURE;

reacts with

 GAB2REACTOME;

reacts with

 Gnb2IMID;

reacts with

 GNG2NCI_NATURE;

reacts with

 GRB10IMID;

reacts with

 GSNNCI_NATURE;

reacts with

 IL1BNCI_NATURE;

reacts with

 IL1R1NCI_NATURE;

reacts with

 IL2NCI_NATURE;

reacts with

 IL2RANCI_NATURE;

reacts with

 IL2RBNCI_NATURE;

reacts with

 IL2RGNCI_NATURE;

reacts with

 IL3NCI_NATURE;

reacts with

 IL3RANCI_NATURE;

reacts with

 IRS1IMID;

reacts with

 IRS2IMID;

reacts with

 ITGA6NCI_NATURE;

reacts with

 ITGB4NCI_NATURE;

reacts with

 JAK1NCI_NATURE;

reacts with

 JAK2NCI_NATURE;

reacts with

 JAK3NCI_NATURE;

reacts with

 KITREACTOME;

reacts with

 LCKNCI_NATURE;

reacts with

 NFKB1NCI_NATURE;

reacts with

 NFKBIANCI_NATURE;

reacts with

 NRASIMID;

reacts with

 PELP1NCI_NATURE;

reacts with

 PIK3C2BNCI_NATURE;

reacts with

 PIK3CAIMID;

reacts with

 PIK3CANCI_NATURE;

reacts with

 PIK3CAREACTOME;

reacts with

 PIK3R1NCI_NATURE;

reacts with

 PIK3R1REACTOME;

reacts with

 PTPN11IMID;

reacts with

 PTPN11NCI_NATURE;

reacts with

 PTPN11REACTOME;

reacts with

 RELANCI_NATURE;

reacts with

 RELNNCI_NATURE;

reacts with

 SHC1IMID;

reacts with

 SHC1NCI_NATURE;

reacts with

 SOS1NCI_NATURE;

reacts with

 SRCNCI_NATURE;

reacts with

 TUBA1AIMID;

reacts with

 VLDLRNCI_NATURE;

reacts with

 YWHAZNCI_NATURE;

state change

 ANGPT1NCI_NATURE;

state change

 ANGPT2NCI_NATURE;

state change

 CBLBIMID;

state change

 CBLNCI_NATURE;

state change

 CD79ANCI_NATURE;

state change

 CD79BNCI_NATURE;

state change

 CDH1NCI_NATURE;

state change

 CDH2NCI_NATURE;

state change

 CSF2RBNCI_NATURE;

state change

 CTNNA1NCI_NATURE;

state change

 CTNND1NCI_NATURE;

state change

 DLG1NCI_NATURE;

state change

 FCER1ANCI_NATURE;

state change

 FCER1GNCI_NATURE;

state change

 FESNCI_NATURE;

state change

 FLT1NCI_NATURE;

state change

 FRS2NCI_NATURE;

state change

 FYNNCI_NATURE;

state change

 GAB1NCI_NATURE;

state change

 IGHENCI_NATURE;

state change

 IL12BNCI_NATURE;

state change

 IL12RB1NCI_NATURE;

state change

 IL23ANCI_NATURE;

state change

 IL23RNCI_NATURE;

state change

 IL2RGNCI_NATURE;

state change

 IL3NCI_NATURE;

state change

 IL3RANCI_NATURE;

state change

 IL4NCI_NATURE;

state change

 IL4RNCI_NATURE;

state change

 IL5NCI_NATURE;

state change

 IL5RANCI_NATURE;

state change

 IRS1NCI_NATURE;

state change

 IRS2NCI_NATURE;

state change

 JAK1NCI_NATURE;

state change

 JAK2NCI_NATURE;

state change

 JAK3NCI_NATURE;

state change

 LYNNCI_NATURE;

state change

 MS4A2NCI_NATURE;

state change

 NGFNCI_NATURE;

state change

 NGFRNCI_NATURE;

state change

 PDGFBNCI_NATURE;

state change

 PDGFRBNCI_NATURE;

state change

 PGFNCI_NATURE;

state change

 PTPN11NCI_NATURE;

state change

 PTPN6NCI_NATURE;

state change

 PVRL3NCI_NATURE;

state change

 RHOANCI_NATURE;

state change

 SDC2NCI_NATURE;

state change

 SHC1NCI_NATURE;

state change

 SRCNCI_NATURE;

state change

 SYKNCI_NATURE;

state change

 TEKNCI_NATURE;

state change

 TYK2NCI_NATURE;

state change

 VAV2NCI_NATURE;

state change

 YWHAZNCI_NATURE;

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