| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4605 |
Name | MYBL2 |
Synonymous | v-myb avian myeloblastosis viral oncogene homolog-like 2;MYBL2;v-myb avian myeloblastosis viral oncogene homolog-like 2 |
Definition | myb-like protein 2|myb-related protein B|v-myb myeloblastosis viral oncogene homolog-like 2 |
Position | 20q13.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | B-Myb(h) + NCOR1(h) <==> B-Myb(h):NCOR1(h) (binding) | B-Myb(h) --> c-myb(h) (DNA binding). | B-Myb(h) --> IGFBP5(h) (DNA binding). | MYBL2(h) --> B-Myb(h) (expression). | C/EBPalpha(h) --/ B-Myb(h) (decrease of abundance) | B-Myb(h) --/ COL1A2(h) (transrepression;) | MYBL2(h) --> B-Myb(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 266 | Phosphothreonine. | Swiss-Prot 53.0 | 393 | Phosphoserine. | Swiss-Prot 53.0 | 440 | Phosphothreonine (by CDK2). | Swiss-Prot 53.0 | 444 | Phosphothreonine (by CDK2). | Swiss-Prot 53.0 | 487 | Phosphothreonine (by CDK2). | Swiss-Prot 53.0 | 494 | Phosphothreonine (by CDK2). | Swiss-Prot 53.0 | 520 | Phosphothreonine (by CDK2). | Swiss-Prot 53.0 | 577 | Phosphoserine (by CDK2). | Swiss-Prot 53.0 | 266 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 444 | Phosphothreonine (CDK2) | 9840932 | Phospho.ELM 6.0 | 487 | Phosphothreonine (CDK2) | 9840932 | Phospho.ELM 6.0 | 494 | Phosphothreonine (CDK2) | 9840932 | Phospho.ELM 6.0 | 577 | Phosphoserine (CDK2) | 9840932 | Phospho.ELM 6.0 | 393 | Phosphoserine | 15302935 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr20 |
Promoter: 41727623 - 41729623 | Agilent_014791 |
chr20 |
Promoter: 41727623 - 41729623 | GoldenGate_Methylation_Cancer_Panel_I |
chr20 |
Promoter: 41727623 - 41729623 | GSE27584 |
chr20 |
Promoter: 41727623 - 41729623 | Agilent_014791_44K |