| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3309 |
Name | HSPA5 |
Synonymous | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa);HSPA5;heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
Definition | 78 kDa glucose-regulated protein|endoplasmic reticulum lumenal Ca(2+)-binding protein grp78|epididymis secretory sperm binding protein Li 89n|immunoglobulin heavy chain-binding protein |
Position | 9q33.3 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | PAK2(h) + GRP78(h) + NCK(h) <==> PAK2(h):GRP78(h):NCK(h) (binding) | GRP78(h) + AR(h) <==> GRP78(h):AR(h) (binding) | GRP78(h) + TRAP170(h) <==> GRP78(h):TRAP170(h) (binding) | Cas(h) + GRP78(h) <==> Cas(h):GRP78(h) (binding) | Lipophilin(h) + GRP78(h) <==> Lipophilin(h):GRP78(h) (binding) | Lipophilin(m) + GRP78(h) <==> Lipophilin(m):GRP78(h) (binding) | AMPKbeta-2(h) + AMPKg(h) + AMPKbeta-1(h) + Hsp50(h) + alpha-tubulin 1B(h) + Hsp90-alpha(h) + Hsp70-1(h) + GRP78(h) + AMPKalpha-1(r) <==> AMPKbeta-2(h):AMPKg(h):AMPKbeta-1(h):Hsp50(h):alpha-tubulin 1B(h):Hsp90-alpha(h):Hsp70-1(h):GRP78(h):AMPKalpha-1(r) (binding) | HSPA5(h) --> GRP78(h) (expression). | HCV-core-1B(HCV1B) --> GRP78(h) (increase of abundance) | HSPA5(h) --> GRP78(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 166 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 571 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr9 |
Promoter: 127042930 - 127044930 | Agilent_014791 |
chr9 |
Promoter: 127042930 - 127044930 | GSE27584 |
chr9 |
Promoter: 127042930 - 127044930 | Agilent_014791_44K |