| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3309 |
Name | HSPA5 |
Synonym | BIP|GRP78|HEL-S-89n|MIF2;heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa);HSPA5;heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
Definition | 78 kDa glucose-regulated protein|endoplasmic reticulum lumenal Ca(2+)-binding protein grp78|epididymis secretory sperm binding protein Li 89n|immunoglobulin heavy chain-binding protein |
Position | 9q33.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Activation of Chaperones by ATF6-alpha;PID Reactome;500130 |
Pathway | Antigen processing and presentation;KEGG PATHWAY;hsa04612 |
Pathway | Parkinson disease;PANTHER;P00049 |
Pathway | Protein export;KEGG PATHWAY;hsa03060 |
Pathway | Diabetes pathways;Reactome;REACT:15380 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | PERK regulated gene expression;PID Reactome;500132 |
Pathway | Activation of Chaperones by IRE1alpha;PID Reactome;500131 |
Pathway | prion pathway;PID BioCarta;100062 |
Pathway | Apoptosis signaling pathway;PANTHER;P00006 |
Pathway | Unfolded Protein Response;PID Reactome;500129 |
Pathway | Platelet degranulation;PID Reactome;500959 |
Pathway | Protein processing in endoplasmic reticulum;KEGG PATHWAY;hsa04141 |
Pathway | Prion diseases;KEGG PATHWAY;hsa05020 |
Disease | HIV infection;FunDO |
Disease | Cancer;FunDO |
Disease | Diabetes mellitus;FunDO |
Disease | Bipolar disorder;FunDO |
External Links | |
Links to Entrez Gene | 3309 |
Links to all GeneRIF Items | 3309 |
Links to iHOP | 3309 |
Sequence Information | |
Nucleotide Sequence | >3309 : length: 3973 GGGCTGGGGGAGGGTATATAAGCCGAGTAGGCGACGGTGAGGTCGACGCCGGCCAAGACA GCACAGACAGATTGACCTATTGGGGTGTTTCGCGAGTGTGAGAGGGAAGCGCCGCGGCCT GTATTTCTAGACCTGCCCTTCGCCTGGTTCGTGGCGCCTTGTGACCCCGGGCCCCTGCCG CCTGCAAGTCGGAAATTGCGCTGTGCTCCTGTGCTACGGCCTGTGGCTGGACTGCCTGCT GCTGCCCAACTGGCTGGCAAGATGAAGCTCTCCCTGGTGGCCGCGATGCTGCTGCTGCTC AGCGCGGCGCGGGCCGAGGAGGAGGACAAGAAGGAGGACGTGGGCACGGTGGTCGGCATC GACCTGGGGACCACCTACTCCTGCGTCGGCGTGTTCAAGAACGGCCGCGTGGAGATCATC GCCAACGATCAGGGCAACCGCATCACGCCGTCCTATGTCGCCTTCACTCCTGAAGGGGAA CGTCTGATTGGCGATGCCGCCAAGAACCAGCTCACCTCCAACCCCGAGAACACGGTCTTT GACGCCAAGCGGCTCATCGGCCGCACGTGGAATGACCCGTCTGTGCAGCAGGACATCAAG TTCTTGCCGTTCAAGGTGGTTGAAAAGAAAACTAAACCATACATTCAAGTTGATATTGGA GGTGGGCAAACAAAGACATTTGCTCCTGAAGAAATTTCTGCCATGGTTCTCACTAAAATG AAAGAAACCGCTGAGGCTTATTTGGGAAAGAAGGTTACCCATGCAGTTGTTACTGTACCA GCCTATTTTAATGATGCCCAACGCCAAGCAACCAAAGACGCTGGAACTATTGCTGGCCTA AATGTTATGAGGATCATCAACGAGCCTACGGCAGCTGCTATTGCTTATGGCCTGGATAAG AGGGAGGGGGAGAAGAACATCCTGGTGTTTGACCTGGGTGGCGGAACCTTCGATGTGTCT CTTCTCACCATTGACAATGGTGTCTTCGAAGTTGTGGCCACTAATGGAGATACTCATCTG GGTGGAGAAGACTTTGACCAGCGTGTCATGGAACACTTCATCAAACTGTACAAAAAGAAG ACGGGCAAAGATGTCAGGAAAGACAATAGAGCTGTGCAGAAACTCCGGCGCGAGGTAGAA AAGGCCAAACGGGCCCTGTCTTCTCAGCATCAAGCAAGAATTGAAATTGAGTCCTTCTAT GAAGGAGAAGACTTTTCTGAGACCCTGACTCGGGCCAAATTTGAAGAGCTCAACATGGAT CTGTTCCGGTCTACTATGAAGCCCGTCCAGAAAGTGTTGGAAGATTCTGATTTGAAGAAG TCTGATATTGATGAAATTGTTCTTGTTGGTGGCTCGACTCGAATTCCAAAGATTCAGCAA CTGGTTAAAGAGTTCTTCAATGGCAAGGAACCATCCCGTGGCATAAACCCAGATGAAGCT GTAGCGTATGGTGCTGCTGTCCAGGCTGGTGTGCTCTCTGGTGATCAAGATACAGGTGAC CTGGTACTGCTTGATGTATGTCCCCTTACACTTGGTATTGAAACTGTGGGAGGTGTCATG ACCAAACTGATTCCAAGGAACACAGTGGTGCCTACCAAGAAGTCTCAGATCTTTTCTACA GCTTCTGATAATCAACCAACTGTTACAATCAAGGTCTATGAAGGTGAAAGACCCCTGACA AAAGACAATCATCTTCTGGGTACATTTGATCTGACTGGAATTCCTCCTGCTCCTCGTGGG GTCCCACAGATTGAAGTCACCTTTGAGATAGATGTGAATGGTATTCTTCGAGTGACAGCT GAAGACAAGGGTACAGGGAACAAAAATAAGATCACAATCACCAATGACCAGAATCGCCTG ACACCTGAAGAAATCGAAAGGATGGTTAATGATGCTGAGAAGTTTGCTGAGGAAGACAAA AAGCTCAAGGAGCGCATTGATACTAGAAATGAGTTGGAAAGCTATGCCTATTCTCTAAAG AATCAGATTGGAGATAAAGAAAAGCTGGGAGGTAAACTTTCCTCTGAAGATAAGGAGACC ATGGAAAAAGCTGTAGAAGAAAAGATTGAATGGCTGGAAAGCCACCAAGATGCTGACATT GAAGACTTCAAAGCTAAGAAGAAGGAACTGGAAGAAATTGTTCAACCAATTATCAGCAAA CTCTATGGAAGTGCAGGCCCTCCCCCAACTGGTGAAGAGGATACAGCAGAAAAAGATGAG TTGTAGACACTGATCTGCTAGTGCTGTAATATTGTAAATACTGGACTCAGGAACTTTTGT TAGGAAAAAATTGAAAGAACTTAAGTCTCGAATGTAATTGGAATCTTCACCTCAGAGTGG AGTTGAAACTGCTATAGCCTAAGCGGCTGTTTACTGCTTTTCATTAGCAGTTGCTCACAT GTCTTTGGGTGGGGGGGAGAAGAAGAATTGGCCATCTTAAAAAGCGGGTAAAAAACCTGG GTTAGGGTGTGTGTTCACCTTCAAAATGTTCTATTTAACAACTGGGTCATGTGCATCTGG TGTAGGAAGTTTTTTCTACCATAAGTGACACCAATAAATGTTTGTTATTTACACTGGTCT AATGTTTGTGAGAAGCTTCTAATTAGATCAATTACTTATTTTAGGAAATTTAAGACTAGA TACTCGTGTGTGGGGTGAGGGGAGGGAGTATTTGGTATGTTGGGATAAGGAAACACTTCT ATTTAATGCTTCCAGGGATTTTTTTTTTTTTTTTTAACCCTCCTGGGCCCAAGTGATCCT TCCACCTCAGTCTCCCAGCTAATTGAGACCACAGGCTTGTTACCACCATGCTCGGCTTTT GCATTAATCTAAGAAAAGGGGAGAGAAGTTAATCCACATCTTTACTCAGGCAAGGGGCAT TTCACAGTGCCCAAGAGTGGGGTTTTCTTGAACATACTTGGTTTCCTATTTCCCCTTATC TTTCTAAAACTGCCTTTCTGGTGGCTTTTTTTAAAATTATTACTAATGATGCTTTTATAG CTGCTTGGATTCTCTGAGAAATGATGGGGAGTGAGTGATCACTGGTATTAACTTTATACA CTTGGATTTCATTTGTAACTTTAGGATGTAAAGGTATATTGTGAACCCTAGCTGTGTCAG AATCTCCATCCCTGAAATTTCTCATTAGTGGTACTGGGGTGGGATCTTGGATGGTGACAT TGAAACTACACTAAATCCCCTCACTATGAATGGGTTGTTAAAGGCAATGGTTTGTGTCAA AACTGGTTTAGGATTACTTAGATTGTGTTCCTGAAGAAAAGAGTCCAGGTAAATGGTATG ATCAATAAAGGACAGGCTGGTGCTAACATAAAATCCAATATTGTAATCCTAGCACTTTGG GAGGCCAAGGCGGGTGGATCACAAGGTCAAGAGATAGAGACCATCTTTGCCAACATGGTG AAACTCCATCTCTACTGAAAATACAAAAATTAGCTGGGCGTGGTAGTGCAAGCTGAAGGC TGAGGCAGGAGAATCACTCGAACCCGGGAGGCAGAGGTTGCAGTGAGCCGAGATCACACC ACTGTACTCCAGCCCGGCACTCCAGCCTGGCGACAAGAGTGAGACTCCACCTCAAAAAAA AAAAAAAGAATCCAATACTGCCCAAGGATAGGTATTTTATAGATGGGCAACTGGCTGAAA GGTTAATTCTCTAGGGCTAGTAGAACTGGATCCCAACACCAAACTCTTAATTAGACCTAG GCCTCAGCTGCACTGCCCGAAAAGCATTTGGGCAGACCCTGAGCAGAATACTGGTCTCAG GCCAAGCCCAATACAGCCATTAAAGATGACCTACAGTGCTGTGTACCCTGGGGCAATAGG GTTAAATGGTAGTTAGCAACTAGGGCTAGTCTTCCCTTACCTCAAAGGCTCTCACTACCG TGGACCACCTAGTCTGTAACTCTTTCTGAGGAGCTGTTACTGAATATTAAAAAGATAGAC TTCAACTATGAAA |
Protein Sequence | >3309 : length: 654 MKLSLVAAMLLLLSAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTAEKDEL |