Entrez Gene

Basic Information
Gene ID	10397
Name	NDRG1
Synonymous	N-myc downstream regulated 1;NDRG1;N-myc downstream regulated 1
Definition	N-myc downstream-regulated gene 1 protein\|differentiation-related gene 1 protein\|nickel-specific induction protein Cap43\|protein NDRG1\|protein regulated by oxygen-1\|reducing agents and tunicamycin-responsive protein
Position	8q24.3
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
NDRG1(h) + 5 ATP --SGK-1(m.s.)--> NDRG1(h){pT328}{pS330}{pT346}{pT356}{pT366} + 5 ADP (phosphorylation)
NDRG1(h) --> NDRG1(h) (expression).
NDRG1(h) + HCV-NS5A-1B(HCV1B) <==> NDRG1(h):HCV-NS5A-1B(HCV1B) (binding)
NDRG1(h) + 3 ATP --SGK-1(h)--> NDRG1(h){pT346}{pT356}{pT366} + 3 ADP (phosphorylation)
NDRG1(h) + 4 ATP --SGK-1(m.s.)--> NDRG1(h){pT328}{pT346}{pT356}{pT366} + 4 ADP (phosphorylation)
NDRG1(h) --> NDRG1(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
319	Phosphoserine.		Swiss-Prot 53.0
326	Phosphoserine.		Swiss-Prot 53.0
328	Phosphothreonine.		Swiss-Prot 53.0
330	Phosphoserine.		Swiss-Prot 53.0
335	Phosphothreonine (By similarity).		Swiss-Prot 53.0
336	Phosphoserine.		Swiss-Prot 53.0
319	Phosphoserine	15302935	Phospho.ELM 6.0
330	Phosphoserine	15302935	Phospho.ELM 6.0
336	Phosphoserine	15302935	Phospho.ELM 6.0
366	Phosphothreonine	15461589	Phospho.ELM 6.0
346	Phosphothreonine	15461589	Phospho.ELM 6.0
356	Phosphothreonine	15461589	Phospho.ELM 6.0
352	Phosphoserine	15461589	Phospho.ELM 6.0
362	Phosphoserine	15461589	Phospho.ELM 6.0
328	Phosphothreonine	15461589	Phospho.ELM 6.0
342	Phosphoserine	15461589	Phospho.ELM 6.0

Transcription Factors [Top]