Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

10397

Name

NDRG1

Synonymous

N-myc downstream regulated 1;NDRG1;N-myc downstream regulated 1

Definition

N-myc downstream-regulated gene 1 protein|differentiation-related gene 1 protein|nickel-specific induction protein Cap43|protein NDRG1|protein regulated by oxygen-1|reducing agents and tunicamycin-responsive protein

Position

8q24.3

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.657G>T; p.M219I; 8:133250481-133250481

 oesophaguscarcinomaSubstitution - Missense

c.196G>A; p.G66S; 8:133264556-133264556

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.118T>G; p.L40V; 8:133264634-133264634

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.925G>A; p.V309M; 8:133242041-133242041

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.288C>T; p.A96A; 8:133262085-133262085

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1157G>C; p.G386A; 8:133238906-133238906

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.700C>T; p.R234W; 8:133248770-133248770

 skinmalignant_melanomaSubstitution - Missense

c.187C>A; p.H63N; 8:133264565-133264565

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.322G>A; p.A108T; 8:133262051-133262051

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.322G>A; p.A108T; 8:133262051-133262051

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.322G>A; p.A108T; 8:133262051-133262051

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.470T>C; p.V157A; 8:133256844-133256844

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1007C>G; p.S336C; 8:133239056-133239056

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.194T>G; p.I65S; 8:133264558-133264558

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.927G>A; p.V309V; 8:133242039-133242039

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.563C>T; p.P188L; 8:133254570-133254570

 breastcarcinomaSubstitution - Missense

c.1110C>T; p.A370A; 8:133238953-133238953

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.318C>T; p.F106F; 8:133262055-133262055

 skinmalignant_melanomaSubstitution - coding silent

c.33T>A; p.A11A; 8:133284279-133284279

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.974G>A; p.R325Q; 8:133239089-133239089

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.718G>T; p.E240*; 8:133248752-133248752

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.341C>A; p.S114Y; 8:133259216-133259216

 breastcarcinomaSubstitution - Missense

c.734G>C; p.G245A; 8:133248736-133248736

 breastcarcinomaSubstitution - Missense

c.924C>T; p.F308F; 8:133242042-133242042

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.686A>G; p.N229S; 8:133250452-133250452

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.492C>T; p.N164N; 8:133256822-133256822

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.64-6T>C; p.?; 8:133280273-133280273

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaUnknown

c.64-6T>C; p.?; 8:133280273-133280273

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaUnknown

c.882G>A; p.Q294Q; 8:133244364-133244364

 breastcarcinomaSubstitution - coding silent

c.321C>T; p.P107P; 8:133262052-133262052

 skinmalignant_melanomaSubstitution - coding silent

c.755+10T>C; p.?; 8:133248705-133248705

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaUnknown

c.805G>A; p.V269M; 8:133247877-133247877

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.616G>A; p.E206K; 8:133250522-133250522

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.1100G>A; p.S367N; 8:133238963-133238963

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.294C>A; p.G98G; 8:133262079-133262079

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.289C>A; p.P97T; 8:133262084-133262084

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.843C>T; p.T281T; 8:133246628-133246628

 skinmalignant_melanomaSubstitution - coding silent

c.368C>A; p.P123H; 8:133259189-133259189

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.269C>T; p.A90V; 8:133262104-133262104

 NSmalignant_melanomaSubstitution - Missense

c.677T>C; p.L226P; 8:133250461-133250461

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.731C>T; p.P244L; 8:133248739-133248739

 skinmalignant_melanomaSubstitution - Missense

c.861G>A; p.A287A; 8:133244385-133244385

 skinmalignant_melanomaSubstitution - coding silent

c.861G>A; p.A287A; 8:133244385-133244385

 skinmalignant_melanomaSubstitution - coding silent

c.996C>T; p.S332S; 8:133239067-133239067

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.849C>T; p.L283L; 8:133246622-133246622

 skinmalignant_melanomaSubstitution - coding silent

c.17A>G; p.Q6R; 8:133284295-133284295

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.17A>G; p.Q6R; 8:133284295-133284295

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.82C>T; p.Q28*; 8:133280249-133280249

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.478C>A; p.L160I; 8:133256836-133256836

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.578C>G; p.S193C; 8:133254555-133254555

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1126C>T; p.P376S; 8:133238937-133238937

 skinmalignant_melanomaSubstitution - Missense

c.57_58delAG; p.E21fs*10; 8:133284254-133284255

 skinmalignant_melanomaDeletion - Frameshift

c.72C>T; p.T24T; 8:133280259-133280259

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.114G>T; p.E38D; 8:133264638-133264638

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.112G>A; p.E38K; 8:133264640-133264640

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.49G>T; p.V17L; 8:133284263-133284263

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1155C>G; p.A385A; 8:133238908-133238908

 breastcarcinomaSubstitution - coding silent

c.616G>C; p.E206Q; 8:133250522-133250522

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.818A>G; p.N273S; 8:133246653-133246653

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.46T>C; p.L16L; 8:133284266-133284266

 skinmalignant_melanomaSubstitution - coding silent

c.808-9C>T; p.?; 8:133246672-133246672

 livercarcinomaUnknown

c.808-9C>T; p.?; 8:133246672-133246672

 livercarcinomaUnknown

c.672G>A; p.L224L; 8:133250466-133250466

 livercarcinomaSubstitution - coding silent

c.1086C>A; p.S362R; 8:133238977-133238977

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.100G>A; p.E34K; 8:133264652-133264652

 skinmalignant_melanomaSubstitution - Missense

c.303C>A; p.D101E; 8:133262070-133262070

 prostatecarcinomaSubstitution - Missense

c.484C>G; p.L162V; 8:133256830-133256830

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1055G>T; p.S352I; 8:133239008-133239008

 thyroidother; neoplasmSubstitution - Missense

c.506C>T; p.A169V; 8:133256808-133256808

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.871G>A; p.G291S; 8:133244375-133244375

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.168G>A; p.R56R; 8:133264584-133264584

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.73G>A; p.G25S; 8:133280258-133280258

 skinmalignant_melanomaSubstitution - Missense

c.211A>G; p.T71A; 8:133262162-133262162

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.732G>A; p.P244P; 8:133248738-133248738

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.836_837insA; p.T281fs*23; 8:133246634-133246635

 stomachcarcinoma; intestinal_adenocarcinomaInsertion - Frameshift

c.66C>A; p.T22T; 8:133280265-133280265

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.424G>A; p.G142S; 8:133258392-133258392

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.195C>A; p.I65I; 8:133264557-133264557

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1052G>A; p.R351Q; 8:133239011-133239011

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.815G>A; p.C272Y; 8:133246656-133246656

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.815G>A; p.C272Y; 8:133246656-133246656

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1156G>A; p.G386R; 8:133238907-133238907

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.636C>T; p.R212R; 8:133250502-133250502

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

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