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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

998

Name

CDC42

Synonymous

cell division cycle 42;CDC42;cell division cycle 42

Definition

G25K GTP-binding protein|GTP binding protein, 25kDa|GTP-binding protein, 25kD|cell division control protein 42 homolog|dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD))|dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD))|growth

Position

1p36.1

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.202C>T; p.R68*; 1:22086462-22086462

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.289-9delT; p.?; 1:22086660-22086660

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.289-9delT; p.?; 1:22086660-22086660

 oesophagus; lower_thirdcarcinoma; adenocarcinomaUnknown

c.289-9delT; p.?; 1:22086660-22086660

 stomachadenocarcinomaUnknown

c.218C>T; p.P73L; 1:22086478-22086478

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.357C>G; p.L119L; 1:22086737-22086737

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - coding silent

c.557G>A; p.R186H; 1:22091498-22091498

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.557G>A; p.R186H; 1:22091498-22091498

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.364G>A; p.D122N; 1:22086744-22086744

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.209T>C; p.L70P; 1:22086469-22086469

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.346C>G; p.Q116E; 1:22086726-22086726

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.310C>T; p.H104Y; 1:22086690-22086690

 skinmalignant_melanomaSubstitution - Missense

c.553A>T; p.S185C; 1:22091494-22091494

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.511G>A; p.E171K; 1:22091452-22091452

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.188A>T; p.D63V; 1:22086448-22086448

 thyroidcarcinomaSubstitution - Missense

c.194A>T; p.D65V; 1:22086454-22086454

 skinmalignant_melanomaSubstitution - Missense

c.90G>T; p.S30S; 1:22078568-22078568

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.381G>T; p.E127D; 1:22086761-22086761

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.496A>G; p.K166E; 1:22091437-22091437

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.186G>T; p.E62D; 1:22086446-22086446

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.143G>A; p.G48E; 1:22081759-22081759

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.450G>T; p.K150N; 1:22086830-22086830

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.197G>A; p.R66K; 1:22086457-22086457

 skinmalignant_melanomaSubstitution - Missense

c.498G>T; p.K166N; 1:22091439-22091439

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.456C>G; p.V152V; 1:22086836-22086836

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - coding silent

c.172A>G; p.T58A; 1:22081788-22081788

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.283G>C; p.E95Q; 1:22086543-22086543

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.439C>A; p.R147S; 1:22086819-22086819

 skinmalignant_melanomaSubstitution - Missense

c.30C>T; p.G10G; 1:22078508-22078508

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.297T>A; p.P99P; 1:22086677-22086677

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.35G>T; p.G12V; 1:22078513-22078513

 NSmalignant_melanomaSubstitution - Missense

c.89C>T; p.S30L; 1:22078567-22078567

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_relatedSubstitution - Missense

c.89C>T; p.S30L; 1:22078567-22078567

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.89C>T; p.S30L; 1:22078567-22078567

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.178+7A>G; p.?; 1:22081801-22081801

 stomachcarcinoma; adenocarcinomaUnknown

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