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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

9212

Name

AURKB

Synonymous

aurora kinase B;AURKB;aurora kinase B

Definition

ARK-2|STK-1|aurora 1|aurora kinase B-Sv1|aurora kinase B-Sv2|aurora- and Ipl1-like midbody-associated protein 1|aurora-1|aurora-B|aurora-related kinase 2|aurora/IPL1-related kinase 2|protein phosphatase 1, regulatory subunit 48|serine/threonine kinase 12|

Position

17p13.1

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.279G>A; p.L93L; 17:8207295-8207295

 breastcarcinomaSubstitution - coding silent

c.753T>G; p.N251K; 17:8205324-8205324

 skinmalignant_melanomaSubstitution - Missense

c.753T>G; p.N251K; 17:8205324-8205324

 skinmalignant_melanomaSubstitution - Missense

c.303C>T; p.F101F; 17:8207271-8207271

 skinmalignant_melanomaSubstitution - coding silent

c.383T>C; p.I128T; 17:8207191-8207191

 breastcarcinomaSubstitution - Missense

c.801G>T; p.L267L; 17:8205276-8205276

 livercarcinomaSubstitution - coding silent

c.801G>T; p.L267L; 17:8205276-8205276

 livercarcinomaSubstitution - coding silent

c.843C>T; p.T281T; 17:8205234-8205234

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.296G>A; p.S99N; 17:8207278-8207278

 pancreascarcinomaSubstitution - Missense

c.972C>T; p.H324H; 17:8204934-8204934

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.893T>C; p.M298T; 17:8205013-8205013

 thyroidother; neoplasmSubstitution - Missense

c.893T>C; p.M298T; 17:8205013-8205013

 thyroidother; neoplasmSubstitution - Missense

c.1010C>T; p.P337L; 17:8204896-8204896

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.705C>T; p.G235G; 17:8205372-8205372

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.705C>T; p.G235G; 17:8205372-8205372

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.894G>T; p.M298I; 17:8205012-8205012

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.378C>T; p.I126I; 17:8207196-8207196

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.851G>A; p.R284H; 17:8205226-8205226

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.851G>A; p.R284H; 17:8205226-8205226

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.851G>A; p.R284H; 17:8205226-8205226

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.851G>A; p.R284H; 17:8205226-8205226

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.433T>G; p.Y145D; 17:8206854-8206854

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.953T>C; p.L318P; 17:8204953-8204953

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.633G>T; p.K211N; 17:8206544-8206544

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.415C>T; p.R139C; 17:8206872-8206872

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.415C>T; p.R139C; 17:8206872-8206872

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.687-9C>T; p.?; 17:8205399-8205399

 livercarcinomaUnknown

c.140T>A; p.V47D; 17:8207749-8207749

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.201C>A; p.I67I; 17:8207576-8207576

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.310G>A; p.A104T; 17:8207264-8207264

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.334C>T; p.Q112*; 17:8207240-8207240

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; peripheral_T_cell_lymphoma_unspecifiedSubstitution - Nonsense

c.742C>T; p.R248C; 17:8205335-8205335

 breastcarcinomaSubstitution - Missense

c.89G>A; p.R30Q; 17:8207800-8207800

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.63G>C; p.L21L; 17:8207826-8207826

 breastcarcinoma; lobular_carcinomaSubstitution - coding silent

c.63G>C; p.L21L; 17:8207826-8207826

 breastcarcinoma; lobular_carcinomaSubstitution - coding silent

c.501G>A; p.Q167Q; 17:8206786-8206786

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.743G>A; p.R248H; 17:8205334-8205334

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.789C>T; p.C263C; 17:8205288-8205288

 ovaryother; neoplasmSubstitution - coding silent

c.789C>T; p.C263C; 17:8205288-8205288

 ovaryother; neoplasmSubstitution - coding silent

c.1029C>T; p.V343V; 17:8204877-8204877

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.704G>A; p.G235D; 17:8205373-8205373

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1029C>T; p.V343V; 17:8204877-8204877

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.209G>A; p.R70Q; 17:8207365-8207365

 stomachadenocarcinomaSubstitution - Missense

c.714C>T; p.D238D; 17:8205363-8205363

 pancreascarcinomaSubstitution - coding silent

c.864G>A; p.V288V; 17:8205042-8205042

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.439C>T; p.R147W; 17:8206848-8206848

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_relatedSubstitution - Missense

c.976T>C; p.W326R; 17:8204930-8204930

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.880G>A; p.A294T; 17:8205026-8205026

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.472C>G; p.P158A; 17:8206815-8206815

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.899C>T; p.A300V; 17:8205007-8205007

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.522G>A; p.E174E; 17:8206765-8206765

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.885C>T; p.S295S; 17:8205021-8205021

 livercarcinoma; hepatocellular_carcinomaSubstitution - coding silent

c.885C>T; p.S295S; 17:8205021-8205021

 thyroidother; neoplasmSubstitution - coding silent

c.885C>T; p.S295S; 17:8205021-8205021

 thyroidother; neoplasmSubstitution - coding silent

c.80G>A; p.R27Q; 17:8207809-8207809

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.820G>C; p.E274Q; 17:8205257-8205257

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.895G>A; p.G299R; 17:8205011-8205011

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.63G>T; p.L21L; 17:8207826-8207826

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.938C>T; p.S313L; 17:8204968-8204968

 skinmalignant_melanomaSubstitution - Missense

c.938C>T; p.S313L; 17:8204968-8204968

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.88C>T; p.R30W; 17:8207801-8207801

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1030G>A; p.A344T; 17:8204876-8204876

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.821A>G; p.E274G; 17:8205256-8205256

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.206+9C>T; p.?; 17:8207562-8207562

 ovaryother; neoplasmUnknown

c.206+9C>T; p.?; 17:8207562-8207562

 ovaryother; neoplasmUnknown

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