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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

6722

Name

SRF

Synonymous

serum response factor (c-fos serum response element-binding transcription factor);SRF;serum response factor (c-fos serum response element-binding transcription factor)

Definition

serum response factor

Position

6p21.1

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1056C>T; p.A352A; 6:43176561-43176561

 skinmalignant_melanomaSubstitution - coding silent

c.379G>A; p.V127M; 6:43172035-43172035

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.798G>T; p.A266A; 6:43175723-43175723

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1363C>T; p.P455S; 6:43178814-43178814

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1255C>T; p.P419S; 6:43178386-43178386

 skinmalignant_melanomaSubstitution - Missense

c.606G>C; p.L202L; 6:43173939-43173939

 breastcarcinomaSubstitution - coding silent

c.627G>C; p.E209D; 6:43173960-43173960

 breastcarcinomaSubstitution - Missense

c.733G>T; p.D245Y; 6:43174066-43174066

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1188G>A; p.T396T; 6:43178319-43178319

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.675A>G; p.P225P; 6:43174008-43174008

 kidneyother; neoplasmSubstitution - coding silent

c.1360G>A; p.V454I; 6:43178811-43178811

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1043G>T; p.G348V; 6:43176548-43176548

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1504G>A; p.A502T; 6:43179167-43179167

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.534G>A; p.L178L; 6:43173867-43173867

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1060C>A; p.Q354K; 6:43176565-43176565

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.357G>T; p.A119A; 6:43172013-43172013

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.650C>T; p.T217I; 6:43173983-43173983

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.650C>T; p.T217I; 6:43173983-43173983

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1133A>G; p.D378G; 6:43176638-43176638

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; peripheral_T_cell_lymphoma_unspecifiedSubstitution - Missense

c.1096C>A; p.P366T; 6:43176601-43176601

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.685G>A; p.D229N; 6:43174018-43174018

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1096C>A; p.P366T; 6:43176601-43176601

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1252G>A; p.A418T; 6:43178383-43178383

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.765C>T; p.S255S; 6:43174098-43174098

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1298C>T; p.A433V; 6:43178429-43178429

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1298C>T; p.A433V; 6:43178429-43178429

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.961A>G; p.T321A; 6:43175886-43175886

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1124G>A; p.S375N; 6:43176629-43176629

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1368G>A; p.Q456Q; 6:43178819-43178819

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.1375C>T; p.L459L; 6:43178826-43178826

 skinmalignant_melanomaSubstitution - coding silent

c.1097C>T; p.P366L; 6:43176602-43176602

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1476C>T; p.T492T; 6:43179139-43179139

 skinmalignant_melanomaSubstitution - coding silent

c.1228C>T; p.P410S; 6:43178359-43178359

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.887C>G; p.S296C; 6:43175812-43175812

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1036A>G; p.M346V; 6:43175961-43175961

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.550C>T; p.L184L; 6:43173883-43173883

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1043-1G>T; p.?; 6:43176547-43176547

 lungcarcinoma; squamous_cell_carcinomaUnknown

c.681T>C; p.R227R; 6:43174014-43174014

 kidneyother; neoplasmSubstitution - coding silent

c.1059G>T; p.Q353H; 6:43176564-43176564

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1426C>A; p.H476N; 6:43178877-43178877

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.893C>A; p.P298H; 6:43175818-43175818

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1219A>G; p.M407V; 6:43178350-43178350

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.639A>G; p.A213A; 6:43173972-43173972

 kidneyother; neoplasmSubstitution - coding silent

c.993C>T; p.V331V; 6:43175918-43175918

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1456G>T; p.G486W; 6:43179119-43179119

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.451A>C; p.I151L; 6:43172107-43172107

 skinmalignant_melanomaSubstitution - Missense

c.1297G>A; p.A433T; 6:43178428-43178428

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1297G>A; p.A433T; 6:43178428-43178428

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1174G>A; p.A392T; 6:43178305-43178305

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1073A>G; p.Q358R; 6:43176578-43176578

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1138A>G; p.T380A; 6:43176643-43176643

 lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.1140G>A; p.T380T; 6:43176645-43176645

 pancreascarcinomaSubstitution - coding silent

c.91_93delGGC; p.G35delG; 6:43171747-43171749

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.1194C>T; p.S398S; 6:43178325-43178325

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.655C>A; p.L219I; 6:43173988-43173988

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.516C>A; p.A172A; 6:43173849-43173849

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - coding silent

c.1316C>A; p.S439Y; 6:43178447-43178447

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - Missense

c.1316C>A; p.S439Y; 6:43178447-43178447

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1177A>G; p.T393A; 6:43178308-43178308

 breastcarcinoma; ER-PR-positive_carcinomaSubstitution - Missense

c.1059G>A; p.Q353Q; 6:43176564-43176564

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.693A>C; p.T231T; 6:43174026-43174026

 kidneyother; neoplasmSubstitution - coding silent

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