Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

5580

Name

PRKCD

Synonymous

protein kinase C, delta;PRKCD;protein kinase C, delta

Definition

protein kinase C delta VIII|protein kinase C delta type|tyrosine-protein kinase PRKCD

Position

3p21.31

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1705C>T; p.R569C; 3:53189208-53189208

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.637G>A; p.A213T; 3:53183186-53183186

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1658A>G; p.E553G; 3:53189161-53189161

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1657G>T; p.E553*; 3:53189160-53189160

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1658A>G; p.E553G; 3:53189161-53189161

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1451A>G; p.D484G; 3:53188755-53188755

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.100G>C; p.E34Q; 3:53178522-53178522

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.487G>A; p.A163T; 3:53181554-53181554

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.897C>T; p.S299S; 3:53185612-53185612

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.897C>T; p.S299S; 3:53185612-53185612

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1352+1G>A; p.?; 3:53186696-53186696

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmUnknown

c.897C>T; p.S299S; 3:53185612-53185612

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.1352+1G>A; p.?; 3:53186696-53186696

 large_intestine; caecumcarcinoma; adenocarcinomaUnknown

c.1927C>T; p.R643C; 3:53192162-53192162

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1557_1558CC>TT; p.(=); 3:53189060-53189061

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.199C>T; p.R67C; 3:53179660-53179660

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1609C>T; p.L537F; 3:53189112-53189112

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.147G>A; p.P49P; 3:53179608-53179608

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.199C>T; p.R67C; 3:53179660-53179660

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1196G>A; p.R399Q; 3:53186276-53186276

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.905C>T; p.S302L; 3:53185620-53185620

 skinmalignant_melanomaSubstitution - Missense

c.280C>T; p.R94C; 3:53179741-53179741

 stomachcarcinomaSubstitution - Missense

c.603C>T; p.I201I; 3:53183152-53183152

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.681C>T; p.I227I; 3:53183475-53183475

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1573T>A; p.Y525N; 3:53189076-53189076

 breastcarcinomaSubstitution - Missense

c.1081G>A; p.G361R; 3:53186022-53186022

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - Missense

c.1080C>T; p.F360F; 3:53186021-53186021

 skinmalignant_melanomaSubstitution - coding silent

c.1755G>T; p.R585S; 3:53189884-53189884

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1809C>T; p.F603F; 3:53189938-53189938

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.17G>A; p.R6H; 3:53178439-53178439

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.21C>T; p.I7I; 3:53178443-53178443

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.17G>A; p.R6H; 3:53178439-53178439

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1728G>T; p.K576N; 3:53189231-53189231

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1608C>T; p.V536V; 3:53189111-53189111

 skinmalignant_melanomaSubstitution - coding silent

c.1525T>C; p.C509R; 3:53188829-53188829

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.132G>A; p.L44L; 3:53179593-53179593

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.2026G>T; p.D676Y; 3:53192261-53192261

 skinmalignant_melanomaSubstitution - Missense

c.1480A>G; p.M494V; 3:53188784-53188784

 haematopoietic_and_lymphoid_tissue; central_nervous_systemlymphoid_neoplasm; primary_central_nervous_system_lymphomaSubstitution - Missense

c.842G>A; p.G281D; 3:53184928-53184928

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.17G>T; p.R6L; 3:53178439-53178439

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.17G>T; p.R6L; 3:53178439-53178439

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.17G>T; p.R6L; 3:53178439-53178439

 large_intestine; coloncarcinomaSubstitution - Missense

c.1743+8C>T; p.?; 3:53189254-53189254

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaUnknown

c.17G>T; p.R6L; 3:53178439-53178439

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.16C>T; p.R6C; 3:53178438-53178438

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1084A>T; p.K362*; 3:53186025-53186025

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Nonsense

c.735C>T; p.D245D; 3:53183529-53183529

 skinmalignant_melanomaSubstitution - coding silent

c.2010C>T; p.F670F; 3:53192245-53192245

 skinmalignant_melanomaSubstitution - coding silent

c.18C>T; p.R6R; 3:53178440-53178440

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.18C>T; p.R6R; 3:53178440-53178440

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2010C>T; p.F670F; 3:53192245-53192245

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.2010C>T; p.F670F; 3:53192245-53192245

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.689C>T; p.P230L; 3:53183483-53183483

 parathyroidadenomaSubstitution - Missense

c.520G>T; p.V174L; 3:53181587-53181587

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1383G>A; p.L461L; 3:53187370-53187370

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1383G>A; p.L461L; 3:53187370-53187370

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.315G>T; p.W105C; 3:53179776-53179776

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.74A>C; p.Q25P; 3:53178496-53178496

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1714A>C; p.T572P; 3:53189217-53189217

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1002C>T; p.Y334Y; 3:53185943-53185943

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.961G>A; p.G321R; 3:53185676-53185676

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1589A>G; p.D530G; 3:53189092-53189092

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.875A>G; p.N292S; 3:53184961-53184961

 peritoneum; appendixother; pseudomyxoma_peritoneiSubstitution - Missense

c.1119G>A; p.E373E; 3:53186199-53186199

 prostateadenomaSubstitution - coding silent

c.1119G>A; p.E373E; 3:53186199-53186199

 thyroidother; neoplasmSubstitution - coding silent

c.1349C>T; p.A450V; 3:53186692-53186692

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1558C>A; p.L520I; 3:53189061-53189061

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.201C>T; p.R67R; 3:53179662-53179662

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.199C>A; p.R67S; 3:53179660-53179660

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.219A>G; p.L73L; 3:53179680-53179680

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.636G>T; p.A212A; 3:53183185-53183185

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.104C>T; p.A35V; 3:53178526-53178526

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.104C>T; p.A35V; 3:53178526-53178526

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1198G>A; p.V400M; 3:53186278-53186278

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.145C>T; p.P49S; 3:53179606-53179606

 skinmalignant_melanomaSubstitution - Missense

c.1702C>G; p.P568A; 3:53189205-53189205

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1464G>T; p.K488N; 3:53188768-53188768

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.385C>T; p.Q129*; 3:53181452-53181452

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1581C>A; p.F527L; 3:53189084-53189084

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1680C>T; p.I560I; 3:53189183-53189183

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1821C>A; p.N607K; 3:53189950-53189950

 prostatecarcinomaSubstitution - Missense

c.1934C>T; p.S645F; 3:53192169-53192169

 skin; armmalignant_melanomaSubstitution - Missense

c.1197G>A; p.R399R; 3:53186277-53186277

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1298G>A; p.G433E; 3:53186641-53186641

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.1469C>T; p.A490V; 3:53188773-53188773

 haematopoietic_and_lymphoid_tissue; central_nervous_systemlymphoid_neoplasm; primary_central_nervous_system_lymphomaSubstitution - Missense

c.350C>T; p.S117F; 3:53181241-53181241

 skinmalignant_melanomaSubstitution - Missense

c.646C>T; p.R216W; 3:53183195-53183195

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.877C>A; p.Q293K; 3:53184963-53184963

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1549C>T; p.P517S; 3:53188853-53188853

 skinmalignant_melanomaSubstitution - Missense

c.1331G>A; p.R444H; 3:53186674-53186674

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.83G>T; p.C28F; 3:53178505-53178505

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.609G>C; p.K203N; 3:53183158-53183158

 breastcarcinomaSubstitution - Missense

c.1438C>T; p.L480L; 3:53188742-53188742

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.865G>T; p.E289*; 3:53184951-53184951

 breastcarcinomaSubstitution - Nonsense

c.57C>T; p.A19A; 3:53178479-53178479

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1854A>C; p.P618P; 3:53189983-53189983

 breastcarcinomaSubstitution - coding silent

c.1083G>A; p.G361G; 3:53186024-53186024

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1294delG; p.D434fs*2; 3:53186637-53186637

 skinmalignant_melanomaDeletion - Frameshift

c.1294delG; p.D434fs*2; 3:53186637-53186637

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1294delG; p.D434fs*2; 3:53186637-53186637

 skinmalignant_melanomaDeletion - Frameshift

c.1294delG; p.D434fs*2; 3:53186637-53186637

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1906G>C; p.E636Q; 3:53192141-53192141

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1302C>T; p.D434D; 3:53186645-53186645

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.972G>A; p.G324G; 3:53185687-53185687

 skinmalignant_melanomaSubstitution - coding silent

c.825G>T; p.K275N; 3:53184911-53184911

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.355C>T; p.Q119*; 3:53181246-53181246

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.1978T>C; p.F660L; 3:53192213-53192213

 skinmalignant_melanomaSubstitution - Missense

c.599G>A; p.C200Y; 3:53183148-53183148

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.73C>T; p.Q25*; 3:53178495-53178495

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.110G>A; p.S37N; 3:53178532-53178532

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.430C>T; p.R144C; 3:53181497-53181497

 skinmalignant_melanomaSubstitution - Missense

c.1503G>A; p.G501G; 3:53188807-53188807

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1702C>T; p.P568S; 3:53189205-53189205

 skinmalignant_melanomaSubstitution - Missense

c.1555-1G>C; p.?; 3:53189057-53189057

 breastcarcinomaUnknown

c.293A>C; p.N98T; 3:53179754-53179754

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.571C>T; p.Q191*; 3:53181732-53181732

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - Nonsense

c.173C>T; p.T58M; 3:53179634-53179634

 pancreascarcinoid-endocrine_tumourSubstitution - Missense

c.436G>A; p.G146R; 3:53181503-53181503

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.173C>T; p.T58M; 3:53179634-53179634

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.277G>A; p.E93K; 3:53179738-53179738

 breastcarcinomaSubstitution - Missense

c.1090C>T; p.L364L; 3:53186170-53186170

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1707C>A; p.R569R; 3:53189210-53189210

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.705T>C; p.V235V; 3:53183499-53183499

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1443G>A; p.L481L; 3:53188747-53188747

 skinmalignant_melanomaSubstitution - coding silent

c.1631G>A; p.G544D; 3:53189134-53189134

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1692G>A; p.T564T; 3:53189195-53189195

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1213G>A; p.A405T; 3:53186293-53186293

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1576A>G; p.T526A; 3:53189079-53189079

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1491G>A; p.E497E; 3:53188795-53188795

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1293_1294insG; p.D434fs*13; 3:53186636-53186637

 large_intestine; caecumcarcinoma; adenocarcinomaInsertion - Frameshift

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