Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

3661

Name

IRF3

Synonymous

interferon regulatory factor 3;IRF3;interferon regulatory factor 3

Definition

-

Position

19q13.3-q13.4

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.793C>T; p.L265L; 19:49662137-49662137

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.793C>T; p.L265L; 19:49662137-49662137

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.722G>A; p.W241*; 19:49662208-49662208

 skinmalignant_melanomaSubstitution - Nonsense

c.950G>A; p.G317E; 19:49661980-49661980

 breastcarcinomaSubstitution - Missense

c.669G>A; p.P223P; 19:49662261-49662261

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.782T>A; p.V261E; 19:49662148-49662148

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.307C>T; p.P103S; 19:49663373-49663373

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.418C>T; p.L140L; 19:49662608-49662608

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.411A>G; p.E137E; 19:49662615-49662615

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.681G>A; p.R227R; 19:49662249-49662249

 skinmalignant_melanomaSubstitution - coding silent

c.601+1G>A; p.?; 19:49662424-49662424

 thyroidcarcinomaUnknown

c.1137_1138CC>TT; p.R380W; 19:49659794-49659795

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1182C>T; p.H394H; 19:49659750-49659750

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.303C>T; p.H101H; 19:49663377-49663377

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.111T>C; p.P37P; 19:49664728-49664728

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.686T>G; p.V229G; 19:49662244-49662244

 breastcarcinomaSubstitution - Missense

c.686T>G; p.V229G; 19:49662244-49662244

 breastcarcinomaSubstitution - Missense

c.679C>T; p.R227W; 19:49662251-49662251

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.894G>T; p.E298D; 19:49662036-49662036

 thyroidother; neoplasmSubstitution - Missense

c.394A>G; p.T132A; 19:49663202-49663202

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.305A>T; p.D102V; 19:49663375-49663375

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1258delG; p.D420fs*>8; 19:49659674-49659674

 livercarcinoma; hepatocellular_carcinomaDeletion - Frameshift

c.1215C>T; p.S405S; 19:49659717-49659717

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.583C>A; p.L195M; 19:49662443-49662443

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.409G>A; p.E137K; 19:49662617-49662617

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1280G>C; p.S427T; 19:49659652-49659652

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1280G>C; p.S427T; 19:49659652-49659652

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1280G>C; p.S427T; 19:49659652-49659652

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.242G>A; p.R81H; 19:49663438-49663438

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.496C>T; p.P166S; 19:49662530-49662530

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.808G>T; p.G270W; 19:49662122-49662122

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.285C>A; p.D95E; 19:49663395-49663395

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.506A>G; p.Q169R; 19:49662520-49662520

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.271C>T; p.R91C; 19:49663409-49663409

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.612C>G; p.F204L; 19:49662318-49662318

 livercarcinomaSubstitution - Missense

c.571C>T; p.P191S; 19:49662455-49662455

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.711G>A; p.T237T; 19:49662219-49662219

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.784A>G; p.R262G; 19:49662146-49662146

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.784A>G; p.R262G; 19:49662146-49662146

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.276A>G; p.L92L; 19:49663404-49663404

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.999G>A; p.T333T; 19:49660812-49660812

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1048_1049insG; p.E350fs*>79; 19:49660762-49660763

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.1276G>A; p.E426K; 19:49659656-49659656

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.386G>A; p.G129E; 19:49663210-49663210

 skinmalignant_melanomaSubstitution - Missense

c.644T>A; p.V215D; 19:49662286-49662286

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1137C>G; p.A379A; 19:49659795-49659795

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.731C>G; p.T244R; 19:49662199-49662199

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.603G>A; p.E201E; 19:49662327-49662327

 skinmalignant_melanomaSubstitution - coding silent

c.939G>A; p.K313K; 19:49661991-49661991

 skinmalignant_melanomaSubstitution - coding silent

c.162C>A; p.F54L; 19:49664677-49664677

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.318C>T; p.I106I; 19:49663362-49663362

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.854G>T; p.R285L; 19:49662076-49662076

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.409-3C>T; p.?; 19:49662620-49662620

 livercarcinomaUnknown

c.1043T>G; p.V348G; 19:49660768-49660768

 breastcarcinomaSubstitution - Missense

c.802C>A; p.L268M; 19:49662128-49662128

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1000G>T; p.E334*; 19:49660811-49660811

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.265G>A; p.G89R; 19:49663415-49663415

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.612C>T; p.F204F; 19:49662318-49662318

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1048G>A; p.E350K; 19:49660763-49660763

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.346G>T; p.D116Y; 19:49663250-49663250

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1004G>A; p.G335E; 19:49660807-49660807

 breastcarcinomaSubstitution - Missense

c.243C>T; p.R81R; 19:49663437-49663437

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.206A>G; p.D69G; 19:49663474-49663474

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.782T>C; p.V261A; 19:49662148-49662148

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.909C>T; p.S303S; 19:49662021-49662021

 pancreascarcinomaSubstitution - coding silent

c.826C>T; p.R276W; 19:49662104-49662104

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.826C>T; p.R276W; 19:49662104-49662104

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.102C>T; p.F34F; 19:49664737-49664737

 skinmalignant_melanomaSubstitution - coding silent

c.692C>T; p.S231F; 19:49662238-49662238

 skinmalignant_melanomaSubstitution - Missense

c.1109C>T; p.T370M; 19:49659823-49659823

 breastcarcinomaSubstitution - Missense

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