| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3661 |
Name | IRF3 |
Synonym | interferon regulatory factor 3;IRF3;interferon regulatory factor 3 |
Definition | - |
Position | 19q13.3-q13.4 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Toll-like receptor signaling pathway;KEGG PATHWAY;hsa04620 |
Pathway | RIG-I-like receptor signaling pathway;KEGG PATHWAY;hsa04622 |
Pathway | TRAM Cascade;PID Reactome;500465 |
Pathway | Cytosolic DNA-sensing pathway;KEGG PATHWAY;hsa04623 |
Pathway | Hepatitis C;KEGG PATHWAY;hsa05160 |
Pathway | Toll receptor signaling pathway;PANTHER;P00054 |
Disease | esophageal cancer;GAD |
Disease | Infection;FunDO |
Disease | Rheumatoid arthritis;FunDO |
Disease | Lymphoma;FunDO |
Disease | CANCER;GAD |
Disease | cervical intraepithelial neoplasia grade 3;GAD |
Disease | Hemorrhagic fevers, Viral;FunDO |
Disease | Respiratory tract disease;FunDO |
External Links | |
Links to Entrez Gene | 3661 |
Links to all GeneRIF Items | 3661 |
Links to iHOP | 3661 |
Sequence Information | |
Nucleotide Sequence | >3661 : length: 2497 GGTTTTATTTCAAGAAGTCGATCAAAAAGAAAGCCCCAGCGCTCTAGAGCTCAGCTGACG GGAAAGGGGGTGCGCAGCCTCGAGTTTGAGAGCTACCCGGAGCTCCAAGACAGGGGTGGG TTCCAGCTGCCCGCACGCCCCGACCTTCCATCGTAGGTAACGCGGAAGAGCCCGGGAGAG CGTTGGTGGCGTCCGAGAGCGAGGAGCGGGAAAGAGGATGGGTCTGCACGGAGAGTGGAA AGGCAGGCTGTGTACTCTGGGGAAAGTGGAGCAAGGAAGGAGCTACAGTGGCCGACGCTG GAGGTCGGCTGCAGAAAAACTAGAAAAAGTAGGGAGGAAAGAGGAAAAGAGGAGGCGTCT ACACTGAGGGGGTTCTAGAGAGGGAGGGGTGGACTCCGTAGATGGGGGTAGTTCAGTCTC GAAACCTGGGGCGTGCTCTGTCCTGGAGGAGGGAGGCGGGCAGTCGGAGGGGAATTGAAT GGAAGTTCTGTGTTGGAAATGTTTTGGGAGATCTTCTGTAGGGGGACTGTGGAAGGGGGT CTACATTGGGGTAAGTGCAGGAGGTAGAGGCTTACACGTGAATCGATTCTGCACTGAAAT AACTAGGGAAAGAGGATGCTACCCTGAAAGTGGGGATACTTACTTTCGATGATGTGGGGG AGGGAGGAGGTCTATACTGGCGGAATTGAGGGAGTGGAGGGTCTGCACTGAAGACGCTGG GGAAGGATGTGCCATGGATATGGGAAGGAACCCTAGCTGATTAGAGAGCCTCTCGGGAGG ATGGGAGGATGGGAAGAGGAGGTTTCCTGTTTGTACCCCCGAAAATATGGGTGAAGGACC TGTGCCGTGGCCCGTGAGAAGGAGGTCTGGGTGCGGAAACTCCAGGCCAGGTGGGTCCGG GGGAGGCCGGTCGCGCCCAGGAAATGCCCTATACGCGCAGGCCGGACCATGGGAACCCCA AAGCCACGGATCCTGCCCTGGCTGGTGTCGCAGCTGGACCTGGGGCAACTGGAGGGCGTG GCCTGGGTGAACAAGAGCCGCACGCGCTTCCGCATCCCTTGGAAGCACGGCCTACGGCAG GATGCACAGCAGGAGGATTTCGGAATCTTCCAGGCCTGGGCCGAGGCCACTGGTGCATAT GTTCCCGGGAGGGATAAGCCAGACCTGCCAACCTGGAAGAGGAATTTCCGCTCTGCCCTC AACCGCAAAGAAGGGTTGCGTTTAGCAGAGGACCGGAGCAAGGACCCTCACGACCCACAT AAAATCTACGAGTTTGTGAACTCAGGAGTTGGGGACTTTTCCCAGCCAGACACCTCTCCG GACACCAATGGTGGAGGCAGTACTTCTGATACCCAGGAAGACATTCTGGATGAGTTACTG GGTAACATGGTGTTGGCCCCACTCCCAGATCCGGGACCCCCAAGCCTGGCTGTAGCCCCT GAGCCCTGCCCTCAGCCCCTGCGGAGCCCCAGCTTGGACAATCCCACTCCCTTCCCAAAC CTGGGGCCCTCTGAGAACCCACTGAAGCGGCTGTTGGTGCCGGGGGAAGAGTGGGAGTTC GAGGTGACAGCCTTCTACCGGGGCCGCCAAGTCTTCCAGCAGACCATCTCCTGCCCGGAG GGCCTGCGGCTGGTGGGGTCCGAAGTGGGAGACAGGACGCTGCCTGGATGGCCAGTCACA CTGCCAGACCCTGGCATGTCCCTGACAGACAGGGGAGTGATGAGCTACGTGAGGCATGTG CTGAGCTGCCTGGGTGGGGGACTGGCTCTCTGGCGGGCCGGGCAGTGGCTCTGGGCCCAG CGGCTGGGGCACTGCCACACATACTGGGCAGTGAGCGAGGAGCTGCTCCCCAACAGCGGG CATGGGCCTGATGGCGAGGTCCCCAAGGACAAGGAAGGAGGCGTGTTTGACCTGGGGCCC TTCATTGTAGCCTGGTGACAGAGTAAGACTCCATCTCGAACAACAAAAAAAAAAGAACTC ATGATTAGGACTGAATTCAGACGCTGGCTGCCCTTGGCCCGCTGTATAACCGAGGCAAAG GACTTTGCCCTGAGCCCGTGGAATCCAAGGATGGTCTCCTCTCTCTACCTGCCTGCCAGC GCTGGGGCTCCTGGGCCCCCAGATCTGATTACCTTCACGGAAGGAAGCGGACGCTCACCA CGCTATGCCCTCTGGTTCTGTGTGGGGGAGTCATGGCCCCAGGACCAGCCGTGGACCAAG AGGCTCGTGATGGTCAAGGTTGTGCCCACGTGCCTCAGGGCCTTGGTAGAAATGGCCCGG GTAGGGGGTGCCTCCTCCCTGGAGAATACTGTGGACCTGCACATTTCCAACAGCCACCCA CTCTCCCTCACCTCCGACCAGTACAAGGCCTACCTGCAGGACTTGGTGGAGGGCATGGAT TTCCAGGGCCCTGGGGAGAGCTGAGCCCTCGCTCCTCATGGTGTGCCTCCAACCCCCCTG TTCCCCACCACCTCAACCAATAAACTGGTTCCTGCTA |
Protein Sequence | >3661 : length: 452 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL PNSGHGPDGEVPKDKEGGVFDLGPFIVGSWAPRSDYLHGRKRTLTTLCPLVLCGGVMAPG PAVDQEARDGQGCAHVPQGLGRNGPGRGCLLPGEYCGPAHFQQPPTLPHLRPVQGLPAGL GGGHGFPGPWGELSPRSSWCASNPPVPHHLNQ |